Search results for "computer"
showing 10 items of 30657 documents
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives
2014
A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…
Overview of Power Electronic Switches: A Summary of the Past, State-of-the-Art and Illumination of the Future.
2020
As the need for green and effective utilization of energy continues to grow, the advancements in the energy and power electronics industry are constantly driven by this need, as both industries are intertwined for obvious reasons. The developments in the power electronics industry has over the years hinged on the progress of the semiconductor device industry. The semiconductor device industry could be said to be on the edge of a turn into a new era, a paradigm shift from the conventional silicon devices to the wide band gap semiconductor technologies. While a lot of work is being done in research and manufacturing sectors, it is important to look back at the past, evaluate the current progr…
Can we automate expert-based journal rankings? Analysis of the Finnish publication indicator
2020
The publication indicator of the Finnish research funding system is based on a manual ranking of scholarly publication channels. These ranks, which represent the evaluated quality of the channels, are continuously kept up to date and thoroughly reevaluated every four years by groups of nominated scholars belonging to different disciplinary panels. This expert-based decision-making process is informed by available citation-based metrics and other relevant metadata characterizing the publication channels. The purpose of this paper is to introduce various approaches that can explain the basis and evolution of the quality of publication channels, i.e., ranks. This is important for the academic …
External Assessors as “Reviewers” for Quality Assurance of Open Access Journals
2017
In Pursuit of Measuring Pre-reflective Music Listening Experiences
2022
While the diverse effects and uses of music and sound have been extensively documented within music psychology, relatively little attention has been paid to the process and experience of listening itself. Previous literature have, however, considered different ways of attending to sounds via the concept of listening modes, which highlights the different ways and strategies through which listeners intentionally orientate themselves to the activity of listening and creating the experiential meaning of the sound. In this paper, we continue on these lines by focusing on the very basic attentional dispositions for listening that often remain unconscious. As op posed to more deliberate and intent…
Applying video games in language learning and teaching : the learner perspective: a case study
2012
Tutkielman tarkoituksena on selvittää oppijoiden näkemyksiä videopelien nykyisistä ja mahdollisista käyttötavoista kieltenopetuksessa ottaen huomioon koehenkilöiden koulutus- ja pelaajataustan. Pelitutkimusta ei ole vielä tehty kauaa, joten ala on hajanainen, mutta tämä tutkimus pohjautuu tietokoneavusteisen oppimisen (CALL) ja videopeleihin perustuvan oppimisen (DGBL) tutkimukseen. CALL ei keskity erikseen pelien käyttöön tai käsittelee enemmän kieltenoppimiseen tehtyjä ohjelmia, kun taas peleihin perustuvassa opetuksessa kielet eivät ole erityisasemassa. Oppimistuloksia ja oppijakokemuksia pelien käytöstä on kerätty lähinnä esikoulu- ja peruskouluikäisiltä, joten lukiolaiskokeilu täydentä…
On the rocky road of reading : effects of computer-assisted reading intervention for at-risk children
2010
A Study on the Assessment of Introductory Computational Thinking via Scratch Programming in Primary Schools
2018
Computational thinking (CT), a transversal intellectual foundation integral to computer science, is making its way into compulsory comprehensive education worldwide. Students are expected to attain skills and knowledge in such interdisciplinary CT principles as Algorithmic thinking, Data representation, and Debugging. Problem-solving by designing and manipulating interactive media with Scratch, a graphical programming tool, is popular especially at the primary school level. However, there has been confusion regarding how introductory CT can be operationalized for educational practice. Teachers and students need research-based knowledge for setting appropriate learning goals in addition to i…