Search results for "conditions"
showing 10 items of 891 documents
Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis.
1981
Abstract Treatment of rats with N-nitrosomorpholine (NNM) for 7 weeks led to a focal increase in liver microsomal epoxide hydrolase (EH) as early as 2 weeks after withdrawal of the carcinogen. This treatment also leads to hyperplastic nodules and liver tumors, but much later. At the same early time point, ATPase activity was decreased in the same islands. Most of these areas already had increased γ-glutamyltranspeptidase activity. The increase in EH at this early time point was more distinct than the decrease in ATPase which has thus far been considered a suitable marker of the earliest stages in hepatocarcinogenesis. The focal increase in EH was also observed in all benign hepatomas, but n…
"Card sorting" : a tool for research in ethics on treatment decision-making at the end of life in Alzheimer patients with a life threatening complica…
2011
Abstract Background End stage dementia is a particularly difficult aspect of care for patients with Alzheimer's disease and related dementias. In care institutions, caregivers and family are concerned by treatment decision-making for an acute life threatening complication occurring in Alzheimer patients at the end of life. How should the best treatment pathway be decided: to treat or not to treat? Which arguments are used for decision-making? These are mainly ethical questions which are currently difficult to express and investigate. Methods/Design Cross sectional multicentre study of clinical cases involving 67 health centres (university hospitals, general hospitals, local hospitals and ho…
Load progression criteria in exercise programmes in lower limb tendinopathy: a systematic review
2020
ObjectiveThe objective of this study is to summarise and analyse the current literature about what progression criteria are applied in loading exercise programmes in lower limb tendinopathies and their evidence and effectiveness.DesignSystematic review.MethodsPubMed, Embase, Scopus and PEDrowere searched from inception to 24 September 2020. The inclusion criteria were randomised controlled trials that included patients with midportion Achilles, patellar or gluteal tendinopathy; assessed function, pain or performance; included at least one group where progressive physical exercise was administered as monotherapy; included at least a control group. We excluded studies that included subjects w…
Radiology for Postmortem
2019
Thanatology deals with the study of early and postmortem changes in relation to the estimation of the time since death. These normal postmortem changes depend on internal and external factors, such as body temperature, preexisting conditions, underlying disease or injury, and the postmortem interval.
Markers for gastric cancer premalignant lesions: where do we go?
2012
Only a small proportion of patients infected with <i>Helicobacter pylori</i> develop gastric cancer during their lifetime. At the same time, this type of cancer remains an important cause of mortality globally. The current interventional strategies have not been successful in decreasing the global burden of the disease; therefore, biomarkers for the identification of the individuals at high risk as well as those in the early stage of the disease is of high importance. In addition, predicting the point of no return for the development of the malignancy is of particular interest; whether atrophy, intestinal or spasmolytic polypeptide-expressing metaplasia, or some of their subtype…
Quality of Life and Negative Affectivity at the Patients with Stroke and Musculoskeletal Disorders
2021
Introduction. Stroke can be a severe debilitating medical condition due to its medical consequences. When it occurs at an individual with pre-existent musculoskeletal disorders, the medical recovery becomes more problematic. Some consequences, like negative affectivity and a reduced quality of life intervene to varying degrees. Material and method. Our study included 150 outpatients who were diagnosed with stroke and one of five types of musculoskeletal disorders (low back pain, osteoporosis, hand disorders, hip osteoarthritis, knee osteoarthritis). We divided all the patients in five sub-groups. To assess the negative affectivity (anxiety) and quality of life we administered to the patient…
Social support at work and job satisfaction among midwives: The mediating role of positive affect and work engagement.
2022
Aims: This study examined whether social support at work from superiors and colleagues is associated with positive affect at work, and whether work engagement creates a positive relationship with job satisfaction among midwives. We also investigated whether a positive affect and work engagement mediate the relationship between social support at work and job satisfaction. Design: This was a quantitative cross-sectional study. Methods: Data were collected from 163 midwives working in the Polish public healthcare system between June 2019 and December 2019. Results: There was a direct relationship between support from superiors and colleagues, positive affect at work, work engagement and job sa…
Mindfulness-, hyväksyntä- ja arvopohjaisen (MIHA) ohjelman vaikuttavuus työuupumusoireiden lievittäjänä : tutkimusyhteenveto Muupu-hankkeesta
2016
Työuupumuksen lievittämiseksi on alettu maailmalla käyttää mindfulness-, hyväksyntä- ja arvopohjaisia (MIHA) -menetelmiä. Muupu-tutkimuksen tarkoituksena oli selvittää, voidaanko uudenlaisella, kahdeksanviikkoisella MIHA- ohjelmalla lievittää työuupumusoireita tehokkaasti. Ohjelma toteutettiin ryhmä- ja verkkointervention yhdistelmänä. Muupu-tutkimuksessa selvitettiin sekä ohjelman vaikuttavuutta että sen vaikutusmekanismeja. 218 tutkittavaa satunnaistettiin kahteen ryhmään: MIHA-interventioryhmään ja tavanomaista tukea (TAV) saavien ryhmään. Tutkimuksessa hyödynnettiin myös pilottiryhmän (n = 24) ja heidän vastinpariensa (n = 24) kyselyvastauksia. Noin 80 % tutkittavista oli naisia, ja yli…
Dampness and student-reported social climate: two multilevel mediation models.
2021
Background Little previous research has analysed the relationship between schools' indoor air problems and schools' social climate. In this study, we analysed a) whether observed mould and dampness in a school building relates to students' perceptions of school climate (i.e. teacher-student relationships and class spirit) and b) whether reported subjective indoor air quality (IAQ) at the school level mediates this relationship. Methods The data analysed was created by merging two nationwide data sets: survey data from students, including information on subjective IAQ (N = 25,101 students), and data from schools, including information on mould and dampness in school buildings (N = 222). The …
Warunki dobrego postu według wybranych pisarzy greckich IV-VI w
2020
Praktykowanie postu wśród wyznawców Jezusa Chrystusa należało do istotnych czynności ascetycznych już od pierwszych pokoleń chrześcijaństwa, ponieważ to zalecenie pojawiło się w nauczaniu Zbawiciela. Dlatego pasterze tamtych czasów na różne sposoby zachęcali członków swoich wspólnot do podjęcia okresowego postu, niezależnie od ich zróżnicowanego podejścia do jego przestrzegania. O obecności zagadnienia postu w życiu kościelnym tych wspólnot świadczą teksty homilii, mów i traktatów, w których zamieszczone są zachęty kierowane do wiernych opisujące sposoby przestrzegania zasad postu oraz jego uzdrawiające wartości. Do autorów, którzy zajmowali się tymi kwestiami, należeli m.in. Asteriusz z Am…