Search results for "conformation"

showing 10 items of 1414 documents

Sulphides of the platinum group elements—12. Bis(tetraphenylphosphonium) pentakaidekakissulphido platinates(IV)

1991

Abstract Synthetic routes to tetraphenylphosphonium salts of [PtSx]2− are outlined, where x = 15 or 18. Generally, (PPh4)2[Pt(S5)3] is formed most readily. The compound [(C6H5)4P]2[PtS15], always solvated, has been obtained by synthesis in acetonitrile (sulphur, triethylamine, H2S and [PPh4]2[PtCl6]) and by metathesis (in DMF) from the known hydrated ammonium compound (NH4)2[Pt(S5)3]2H2O+2[Ph4P]Br→(Ph4P)2[Pt(S5)3]· DMF+2NH4Br, and from the dismutation (in acetone) 3PtS172−→PtS152−+2PtS182−. X-ray diffraction shows that crystals obtained from DMF and acetone are the solvated salts [Ph4P]2· [Pt(S5)3]· S, with solvent molecules (S) uncoordinated. In both, the three platinopentathian rings rela…

Inorganic chemistryCyclohexane conformationCrystal structureMetathesisMedicinal chemistryInorganic ChemistrySolventchemistry.chemical_compoundchemistryX-ray crystallographyMaterials ChemistryMoleculePhysical and Theoretical ChemistryAcetonitrileTriethylaminePolyhedron
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Alkaline titrations of poly(dG-dC).poly(dG-dC): microemulsion versus solution behaviour

2007

PolyGC was titrated with a strong base in the presence of increasing concentrations of NaCl (from 0.00 to 0.60M) either in water solution or with the polynucleotide solubilized in the aqueous core of reverse micelles, i.e., the cationic quaternary water-in-oil microemulsion CTAB/n-hexane/n-pentanol/water. The results for matched samples in the two media were compared. CD and UV spectroscopies and, for the solution experiments, pH measurements were used to follow the course of deprotonation. In both media the primary effect of the addition of base was denaturation of the polynucleotide, reversible by back-titration with a strong acid. In solution, the apparent pK(a) of the transition decreas…

Inorganic chemistryPolynucleotidesPolynucleotides; Alkaline titration; Reverse micelles; SpectroscopiesMicellepolynucleotideDeprotonationPolydeoxyribonucleotidesStructural Biologyalkaline titrationDenaturation (biochemistry)MicroemulsionMolecular BiologyAqueous solutionChemistryCetrimoniumCircular DichroismspectroscopiesGeneral MedicineHydrogen-Ion ConcentrationSolutionsFreeze Dryingreverse micelleIonic strengthPolynucleotideCetrimonium CompoundsNucleic Acid ConformationTitrationEmulsionsReverse micelles
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Quaternary and subunit structure of Calliphora arylphorin as deduced from electron microscopy, electrophoresis, and sequence similarities with arthro…

1992

Arylphorin was purified from larvae of the blowfly Calliphora vicina and studied in its oligomeric form and after dissociation at pH 9.6 into native subunits. In accordance with earlier literature, it was electrophoretically shown to be a 500 kDa hexamer (1 x 6) consisting of 78 kDa polypeptides (= subunits). Electron micrographs of negatively stained hexamers show a characteristic curvilinear, equilateral triangle of 12 nm in diameter (top view) and a rectangle measuring 10 x 12 nm (side view). Alternatively, particles in the top view orientation exhibit a roughly circular shape 12 nm in diameter. Crossed immunoelectrophoresis revealed the presence of a major subunit type; the nature of a …

Insectaanimal structuresCalliphora vicinaProtein ConformationPhysiologyStereochemistryProtein subunitmedicine.medical_treatmentMolecular Sequence DataBiologyRandom hexamerBiochemistryCalliphoraEndocrinologyHemolymphmedicineAnimalsAmino Acid SequenceEcology Evolution Behavior and SystematicsGlycoproteinsSequence Homology Amino AcidProtein primary structureSpidersHemocyaninbiology.organism_classificationNephropidaeMicroscopy ElectronBiochemistryInsect HormonesLarvaHemocyaninsInsect ProteinsElectrophoresis Polyacrylamide GelAnimal Science and ZoologyProtein quaternary structureJournal of Comparative Physiology B
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Structure and evolution of the leucine plasmids carried by the endosymbiont (Buchnera aphidicola) from aphids of the family Aphididae.

1998

In all examined species of the family Aphididae, the bacterial endosymbiont Buchnera aphidicola carries a plasmid encoding the genes leuABCD (involved in leucine biosynthesis) along with repA1, repA2 and ORF1. The gene organisation of the leucine plasmids was conserved, except in Buchnera isolated from Pterocomma populeum, where ORF1 was located in a different position. An inverted repeat (LIR1) located between repA2 and leuA is found in all of the Buchnera leucine plasmids examined. The predicted secondary structure of the LIR1 transcript conforms to a long hairpin loop, suggesting an involvement in transcription termination or messenger stability. Phylogenetic reconstruction based on repA…

Inverted repeatMolecular Sequence DataSequence alignmentBiologyMicrobiologyOpen Reading FramesPlasmidEnterobacteriaceaeLeucineGeneticsAnimalsAmino Acid SequenceRNA MessengerSymbiosisMolecular BiologyGenePhylogenyRepetitive Sequences Nucleic AcidGeneticsBase SequenceChromosome MappingGene Expression Regulation Bacterialbiochemical phenomena metabolism and nutritionbiology.organism_classificationOpen reading frameRNA BacterialGenes BacterialAphidsHorizontal gene transferNucleic Acid ConformationLeucineBuchneraSequence AlignmentPlasmidsFEMS microbiology letters
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Tracking Ca

2019

We characterize thus-far elusive domain rearrangements of a calcium-transporting ATPase in the native membrane.

Ion TransportProtein ConformationBiophysicsQuantitative Structure-Activity RelationshipSciAdv r-articlesMolecular Dynamics SimulationCrystallography X-RaySarcoplasmic Reticulum Calcium-Transporting ATPasesKineticsStructural BiologyCalciumProtein Interaction Domains and MotifsResearch ArticlesProtein BindingResearch ArticleScience advances
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Isomerism of [64Cu-NOTA-Bn]-labeled radiotracers: separation of two complex isomers and determination of their interconversion energy barrier using i…

2011

The model complex [(64)Cu((S)-p-NH(2)-Bn-NOTA)](-) ([(64)Cu]1) was used to study the isomerism of [(64)Cu-NOTA-Bn]-labeled radiotracers. Two complex isomers [(64)Cu]1a and [(64)Cu]1b, which were formed at a ratio of 1:9 during the complexation of [(64)Cu]Cu(2+) with (S)-p-NH(2)-Bn-NOTA, were separated using ion pair chromatography. To study the interconversion, the nonradioactive complex isomers Cu1a and Cu1b were separated and thermally treated at 90 °C in both ammonium acetate solution and deionized water. A faster interconversion rate was observed for both isomers with lower concentrations of ammonium ions. At the end of reaction, the thermodynamic Cu1a to Cu1b equilibrium ratio was 6:94…

Ion pair chromatographyAnalytical chemistryMolecular Conformationchemistry.chemical_elementAcetatesChemical Fractionation010402 general chemistry01 natural sciencesMolecular conformationIonInorganic Chemistrychemistry.chemical_compoundHeterocyclic Compounds 1-RingDrug StabilityIsomerismCoordination ComplexesHeterocyclic CompoundsAmmoniumPhysical and Theoretical ChemistryRadioactive TracersChromatography010405 organic chemistryChemistryChemical fractionationTemperatureWaterHydrogen-Ion ConcentrationCopper0104 chemical sciencesSolutionsPositron-Emission TomographyPhysical chemistryThermodynamicsAmmonium acetateCopperInorganic chemistry
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Interactions of the alternating double stranded copolymer poly(dA-dT).poly(dA-dT) with NiCl2 and CdCl2: solution behaviour

2007

The thermal denaturation of the synthetic high molecular weight double stranded polynucleotide poly(dA-dT) x poly(dA-dT) has been studied in aqueous buffered solution (Tris 1.0 mM; pH 7.8+/-0.2) in the presence of increasing concentrations of either Ni(2+) (borderline cation) or Cd(2+) (soft cation) at four different constant ionic strength values (NaCl), making use of UV and circular dichroism (CD) spectroscopies. The experimental results show that the B-type double helix of the polymer is stabilized against thermal denaturation in the presence of both cations at low concentrations, relative to the systems where only NaCl is present, in the same conditions of ionic strength and pH. The eff…

IonsCircular DichroismModel polynucleotideOsmolar ConcentrationUV-spectroscopyNickel (II) and Cadmium (II) ionThermal denaturationModel polynucleotides; Thermal denaturation; Nickel (II) and Cadmium (II) ions; Circular Dichroism; UV-spectroscopySolutionsCadmium ChloridePoly dA-dTNickelNucleic Acid ConformationThermodynamics
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[1,2,3]Triazolo[1,5-a]pyridyl phosphines reflecting the influence of phosphorus lone pair orientation on spectroscopic properties

2010

A series of new triazolopyridine-based phosphines has been prepared. These compounds revealed unexpected spectroscopic patterns. In particular, the NMR spectra are highly dependent on the relative conformational preference of the phosphine substituent at C7. Here, we report on their complete NMR analysis, X-ray structures and DFT calculations that confirm the particular arrangement of the phosphorus lone pair orbital related to the substituent pattern of the chosen phosphine.

IonsMagnetic Resonance Spectroscopy[CHIM.ORGA]Chemical Sciences/Organic chemistryPhosphines010405 organic chemistryStereochemistryPhosphorusMolecular ConformationSubstituentchemistry.chemical_elementPhosphorusTriazolesCrystallography X-Ray010402 general chemistry01 natural sciences3. Good health0104 chemical sciencesInorganic ChemistryNMR spectra databasechemistry.chemical_compoundCrystallographychemistryTriazolopyridineLone pairPhosphineDalton Trans.
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Discriminating octahedral transition metal ions: highly selective tripodal tris-(2,2′-bipyridine) functionalized piperazine cyclophane receptor for C…

2011

New tripodal transition metal ion receptors, tris(5-ethoxycarbonyl-2,2'-bipyridine) and tris(5-carboxylate-2,2'-bipyridine) substituted 27-membered trimeric piperazine cyclophanes 5 and 7 as well as tetra(5-ethoxycarbonyl-2,2'-bipyridine) substituted 36-membered tetrameric piperazine cyclophane 6, have been prepared and their transition metal ion complexing properties studied in solution by UV-vis spectroscopy and in the solid state by single-crystal X-ray diffraction. The crystal structures of [H(3)5(3+)·Fe(2+)]·4(ClO(4)(-))·CF(3)COO(-) (V), [H(3)7(2+)·Fe(2+)]·2(SO(4)(2-)) (VII) and the reference complex [tris(5,5'-bis(ethoxycarbonyl)-2,2'-bipyridine)Fe(II) perchlorate] (I) showed that the…

IonsTrisStereochemistryMolecular ConformationCrystal structurePiperazines22'-BipyridineInorganic ChemistryPiperazinechemistry.chemical_compoundPerchlorateCrystallography22'-DipyridylPiperidinesTransition metalchemistryTransition ElementsSpectrophotometry UltravioletSelectivityPiperazineCopperCyclophaneDalton Transactions
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Intramolecular electron transfer between molybdenum and iron mimicking bacterial sulphite dehydrogenase

2014

Diferrocenyl/diferrocenium substituted dioxido molybdenum(VI) complexes [Fe2MoO2] 2(Fc)/[2(FC)]²⁺ mimic the catalytic active site including the redox subunits as well as the catalytic function of bacterial sulphite oxidases.

IronSulfite DehydrogenaseMolecular Conformationchemistry.chemical_elementBiocompatible MaterialsElectronsCrystallography X-RayPhotochemistryRedoxCatalysisCatalysisElectron TransportElectron transferCoordination ComplexesCatalytic DomainPolymer chemistryMaterials ChemistrySulfite dehydrogenaseFerrous CompoundsMolybdenumBacteriabiologyMetals and AlloysActive siteGeneral ChemistryElectron transport chainSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryMolybdenumIntramolecular forceCeramics and Compositesbiology.proteinOxidation-ReductionChemical Communications
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