Search results for "corona"

showing 10 items of 3472 documents

Inflammation and coronary artery disease: The exercise paradox

2018

Adult0301 basic medicinemedicine.medical_specialtyImmunologyMEDLINEInflammationCoronary Artery Disease030204 cardiovascular system & hematologyCoronary AngiographyBiochemistryCoronary artery disease03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansImmunology and AllergyExercise physiologyExerciseMolecular BiologyInflammationbusiness.industryHematologymedicine.disease030104 developmental biologyExercise TestCardiologymedicine.symptombusinessCytokine
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A Trial of Lopinavir–Ritonavir in Covid-19

2020

Adult2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralLopinavir/ritonavirPharmacologyLopinavirBetacoronavirusmedicineHumansPandemicsRitonavirBetacoronaviruPandemicCoronavirus InfectionSARS-CoV-2business.industryCOVID-19LopinavirGeneral MedicineCOVID-19 Drug TreatmentRitonavirCoronavirus InfectionsbusinessCoronavirus InfectionsHumanmedicine.drugNew England Journal of Medicine
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Impact of coronavirus disease 2019 (COVID-19) outbreak on radiology research: An Italian survey

2021

Abstract Purpose To understand how COVID-19 pandemic has changed radiology research in Italy. Methods A questionnaire (n = 19 questions) was sent to all members of the Italian Society of Radiology two months after the first Italian national lockdown was lifted. Results A total of 327 Italian radiologists took part in the survey (mean age: 49 ± 12 years). After national lockdown, the working-flow came back to normal in the vast majority of cases (285/327, 87.2%). Participants reported that a total of 462 radiological trials were recruiting patients at their institutions prior to COVID-19 outbreak, of which 332 (71.9%) were stopped during the emergency. On the other hand, 252 radiological tri…

Adult2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ArticleTrialSurveys and QuestionnairesPandemicSurveys and QuestionnaireHumansMedicineRadiology Nuclear Medicine and imagingPandemicsPractice Policy & EducationPandemicSARS-CoV-2business.industryResearchOutbreakMean ageMiddle AgedItalyRadiology Nuclear Medicine and imagingRadiologistRadiological weaponCommunicable Disease ControlRadiologyRadiologyCovid-19businessHumanClinical Imaging
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SARS-CoV-2 antibody persistence after five and twelve months: A cohort study from South-Eastern Norway

2022

Objectives To assess total antibody levels against Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2) spike protein up to 12 months after Coronavirus Disease (COVID-19) infection in non-vaccinated individuals and the possible predictors of antibody persistence. Methods This is the first part of a prospective multi-centre cohort study. Participants The study included SARS-CoV-2 real-time polymerase chain reaction (RT-PCR) positive and negative participants in South-Eastern Norway from February to December 2020. Possible predictors of SARS-CoV-2 total antibody persistence was assessed. The SARS-CoV-2 total antibody levels against spike protein were measured three to five months aft…

AdultAged 80 and overMaleMultidisciplinaryNorwaySARS-CoV-2COVID-19Middle AgedAntibodies ViralCohort StudiesYoung AdultSpike Glycoprotein CoronavirusHumansFemaleVDP::Medisinske Fag: 700Prospective StudiesAged
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[Descriptive and comparative study of cardiovascular risk factors and physical activity in patients with acute coronary syndrome].

2016

Resumen Objetivo Analizar diversos factores de riesgo cardiovascular en función de la actividad física realizada en pacientes con síndrome coronario agudo (SCA). Diseño Estudio observacional transversal. Emplazamiento Servicio de prevención cardiovascular hospitalario (Departamento Salud, Valencia, España). Participantes Un total de 401 sujetos con SCA y alta hospitalaria entre 2 y 3 meses previos a la medición, entre 30 y 80 años; ausencia de contraindicación para realizar actividad física; sin participación previa en programas de rehabilitación cardiaca. Mediciones principales Se estimó el equivalente metabólico MET (kcal/kg) según el tipo de actividad, frecuencia, duración e intensidad. …

AdultAged 80 and overMalePhysical activityMiddle AgedOriginalesCross-Sectional StudiesCardiovascular DiseasesRisk FactorsFactores de riesgo cardiovascularActividad físicaHumansFemaleSíndrome coronario agudoAcute coronary syndromeExerciseCardiovascular risk factorsAgedAtencion primaria
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Thinking of future as an older individual increases perceived risks for age‐related diseases but not for COVID‐19

2022

Actively thinking of one's future as an older individual could increase perceived risk and risk aversion. This could be particularly relevant for COVID-19, if we consider the common representation of the risk of being infected by COVID-19 as associated with being older. Increased perceived risk could bear consequences on the adoption of preventive behaviours. Thus, we investigated whether increasing the salience of individuals' future as an older adult would impact on their perceived risk for COVID-19 and medical conditions varying for age-relatedness. One hundred and forty-four Italian adults (Mage = 27.72, range: 18–56) were randomly assigned to either a future as older adult thinking or …

AdultAging2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)050109 social psychology050105 experimental psychologyDevelopmental psychologyArts and Humanities (miscellaneous)COVID‐19risk perceptionAge relatedAge priming; Age-related diseases; COVID-19; Future-oriented thinking; Risk perceptionHumansAge‐related diseases0501 psychology and cognitive sciencesGeneral PsychologyAgedage-related diseaseSalience (language)SARS-CoV-2Risk aversion05 social sciencesCOVID-19General MedicineFuture‐oriented thinkingRisk perceptionfuture-oriented thinkingCross-Sectional StudiesItalyRegular Empirical ArticleRegular Empirical ArticlesPsychologyAge-related diseasesage primingInternational Journal of Psychology
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The Quest for Predictors of Shunt-Dependent Chronic Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage: Toward a Tailored Approach for Permanent …

2021

AdultAneurysmal subarachnoid hemorrhage Cerebrospinal fluid (CSF) output External ventricular drainage Hydrocephalus Adult Cerebrospinal Fluid Shunts Chronic Disease Aged Humans Hydrocephalus Ventriculoperitoneal Shunt Predictive Value of Tests Middle Aged Subarachnoid Hemorrhage Risk Assessment Prognosis Treatment OutcomeCerebrospinal fluid (CSF) output2019-20 coronavirus outbreakmedicine.medical_specialtySubarachnoid hemorrhageCoronavirus disease 2019 (COVID-19)Aneurysmal subarachnoid hemorrhageSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Risk AssessmentVentriculoperitoneal ShuntPredictive Value of TestsmedicineHumansAgedbusiness.industryExternal ventricular drainageMiddle AgedSubarachnoid Hemorrhagemedicine.diseasePrognosisChronic hydrocephalusCerebrospinal Fluid ShuntsHydrocephalusShunt (medical)SurgeryTreatment OutcomeChronic DiseaseSurgeryNeurology (clinical)businessHydrocephalus
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Large-scale association analysis identifies new risk loci for coronary artery disease

2016

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching genome-wide significance, taking the number of susceptibility loci for CAD to 46, and a further 104 independent variants (r 2 < 0.2) strongly associated with CAD at a 5% false discovery rate (FDR). Together, these variants explain approximately 10.6% of CAD heritability. Of the 46 genome-wide significant lead SNPs, 12 show a significant association with a lipid trait, and 5 show a significant association with blood pressure, but none is significantly associated with diabetes. Network analysis with 233 candidate genes …

AdultAsian Continental Ancestry GroupMaleCandidate geneBIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICAPopulationEuropean Continental Ancestry GroupQuantitative Trait LociCADGenome-wide association studySingle-nucleotide polymorphismCoronary Artery Disease030204 cardiovascular system & hematologyBiologyQuantitative trait locusBioinformaticsPolymorphism Single NucleotideArticleWhite Peoplecoronary artery disease risk lociCell LineCoronary artery disease03 medical and health sciences0302 clinical medicineAsian PeopleRisk FactorsmedicineHumansgeneticsGene Regulatory NetworksGenetic Predisposition to Diseasecardiovascular diseasesPolymorphismeducation030304 developmental biologyGenetic associationAgedGenetics0303 health scienceseducation.field_of_studyAdult Aged Asian Continental Ancestry Group Cell Line Coronary Artery Disease; genetics European Continental Ancestry Group; genetics Female Gene Regulatory Networks Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Middle Aged Polymorphism; Single Nucleotide Quantitative Trait Loci Risk FactorsSingle NucleotideMiddle Agedmedicine.disease3. Good healthFemaleGenome-Wide Association StudyNature Genetics
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Glycemic variability in type 2 diabetes mellitus and acute coronary syndrome: liraglutide compared with insulin glargine: a pilot study

2020

Objective To explore the glucagon-like peptide-1 analogue liraglutide in the hospital setting in patients with type 2 diabetes mellitus (T2DM) and acute coronary syndrome and to evaluate the safety and efficacy and its impact on hospitalization and short-term glycemic variability (GV). Methods A 12-week, open-label, prospective, randomized pilot clinical study with parallel groups that compared liraglutide (group 1) with glargine (group 2) and its impact on glycemic control and GV. Results Thirteen patients were included. During hospitalization, mean glucose was 164.75 mg/dL (standard deviation [SD] 19.94) in group 1 and 166.69 mg/dL (38.22) in group 2. GV determined by CV and SD was 20.98 …

AdultBlood GlucoseMaleAcute coronary syndromemedicine.medical_specialtyProspective Clinical Research ReportMedicine (General)Hospital settingtype 2 diabetes mellitusGLP-1 receptor agonistInsulin Glargine030209 endocrinology & metabolismPilot Projects030204 cardiovascular system & hematologyHypoglycemiaBiochemistryacute coronary syndrome03 medical and health sciencesRandom Allocation0302 clinical medicineR5-920Internal medicineMedicineHumansHypoglycemic AgentsInsulinGlycemic variabilityGlucagon-like peptide 1 receptorGlycemicGlycated Hemoglobinliraglutidebusiness.industryInsulin glargineLiraglutideBiochemistry (medical)Type 2 Diabetes MellitusCell BiologyGeneral MedicineMiddle Agedmedicine.diseaseHypoglycemiaMetforminDiabetes Mellitus Type 2Glycemic IndexSpainFemalebusinessmedicine.drugJournal of International Medical Research
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The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. The Euro Heart Survey on diabetes and the heart.

2004

Aim The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). Methods and results The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism. Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had a…

AdultBlood GlucoseMaleDiabetes mellitumedicine.medical_specialtyAbnormal glucoseDiabetic AngiopathieOral glucose tolerance testCoronary Artery DiseaseImpaired glucose toleranceCoronary artery diseaseSDG 3 - Good Health and Well-beingRisk FactorsDiabetes mellitusInternal medicineEpidemiologymedicineHumansIn patientAgedGlucose tolerance testmedicine.diagnostic_testbusiness.industryImpaired glucose toleranceGlucose Tolerance TestMiddle Agedmedicine.diseaseSurgeryEuropeDiabetes Mellitus Type 2Blood sugar regulationFemaleCardiology and Cardiovascular MedicinebusinessDiabetic AngiopathiesHumanEuropean heart journal
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