Search results for "coronary"
showing 10 items of 1588 documents
Rhabdomyosarcoma of the head and neck in pediatric patients: a systematic review.
2022
Rhabdomyosarcoma (RMS) is a soft tissue malignant tumor of mesenchymal cell origin, which usually shows variable differentiation of muscle cells. It is the most common solid sarcoma in children. The most usual site of occurrence are the head and neck regions. RMS presents a variety of histologic features, and so differential diagnosis with other small round cell tumors is needed. Hence, it has been very useful to the field to undertake additional immunohistochemical studies to determine the diagnosis and, on occasions, to assign subtype tumors. A systematic review of three databases (Medline, Biological Science Collection and Health & Medical Collection) was carried out with the purpose of …
The Sick Adipose Tissue: New Insights Into Defective Signaling and Crosstalk With the Myocardium
2021
Adipose tissue (AT) biology is linked to cardiovascular health since obesity is associated with cardiovascular disease (CVD) and positively correlated with excessive visceral fat accumulation. AT signaling to myocardial cells through soluble factors known as adipokines, cardiokines, branched-chain amino acids and small molecules like microRNAs, undoubtedly influence myocardial cells and AT function via the endocrine-paracrine mechanisms of action. Unfortunately, abnormal total and visceral adiposity can alter this harmonious signaling network, resulting in tissue hypoxia and monocyte/macrophage adipose infiltration occurring alongside expanded intra-abdominal and epicardial fat depots seen …
Cirurgia coronària amb i sense circulació extracorpòria. Morbimortalitat postoperatòria i seguretat a curt i llarg terme
2016
OBJETIUS: Les malalties cardiovasculars representen el 25-40% de totes les morts a Europa i Amèrica del Nord amb una majoria causada per coronariopaties. La cirurgia de revascularització coronària amb circulació extracorpòria (CEC) segueix sent el “gold stàndard” del tractament quirúrugic d’aquesta patologia. Malgrat la millora de les tècniques i l'experiència quirúrgica, part de la morbiditat relacionada amb la cirurgia coronària és causada per la CEC i és per aquest motiu l’augment de procediments de revascularització coronària sense CEC les darreres dècades. L’ objectiu d’aquesta tesi és descriure l’experiència del nostre centre durant 20 anys (1993-2013) en la cirurgia cardiaca de revas…
Impact of Platelet Reactivity in ACS Patients on Clinical Outcomes with Triple Antithrombotic Therapy
2021
Optimal antithrombotic therapy after percutaneous coronary intervention (PCI) in patients on oral anticoagulants (OAC) remains a clinical conundrum. In fact, combining an OAC with dual antiplatelet therapy (triple antithrombotic therapy, TAT) increases the risk of bleeding. Clopidogrel is the only thienopyridine recommended in TAT patients. Whether its response plays a relevant role in this setting remains uncertain. We aimed to evaluate the level of platelet reactivity inhibition (PRI) achieved by oral TAT in Acute Coronary Syndrome (ACS) patients undergoing PCI and its relationship with outcomes. We performed a multicenter prospective observational study and assessed PRI by vasodilator-st…
Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis.
2003
Inflammation underlies both onset and perpetuation of atherosclerosis. Plasma lipoproteins transport the platelet-activating factor-acetylhydrolase (PAF-AH) with potentially anti-inflammatory activities. Our aim was to determine whether PAF-AH activity was associated with inflammatory markers and with coronary artery disease (CAD). PAF-AH activity and a panel of inflammatory mediators were measured in plasma of 496 patients with CAD and in 477 controls; 276 patients presented with stable angina pectoris and 220 with acute coronary syndrome (ACS). Individuals within the highest quartile of PAF-AH activity had an 1.8-fold increase in CAD risk [95% confidence interval (CI), 1.01 to 3.2; P = 0.…
Pirmreizējas sirds ritma izmaiņas pacientiem pēc atvērtās sirds operācijas
2019
Pēcoperācijas ātriju fibrilācija (POĀF) ir biežākā komplikācija pacientiem, kuriem veikta operācija uz atvērtas sirds. Kā rezultātā tā ietekmē morbiditāti, mortalitāti, kā arī palielina finansiālas izmaksas. Pētījuma mērķis ir uzzināt vai ir korelācija starp veiktiem pirms operācijas standarta izmeklējuma rezultātiem un pēcoperācijas ātriju fibrilāciju. Jo nosakot augsta riska pacientu var uzsākt preventīvu ārstēšanu. Materiāli un metodes: retrospektīvs pētījums, kur tika iekļauti pacienti, kam veikta sirds operācija ar sternotomijas pieeju, kuriem pirms operācijas bija sīnusa ritms n = 111. 39 pacienti netika iekļauti pētījumā, jo pirms operācijas bija ātriju fibrilācija vai anamnēzē ātrij…
The relationship between frailty syndrome and quality of life in older patients following acute coronary syndrome
2019
Purpose: Elderly patients with ST-segment-elevation myocardial infarction (STEMI) have a high risk of mortality, which is particularly high in the first 30 days. Quality of life (QoL) and risk-benefit assessments are of pivotal importance in the elderly. The objective of this study is to assess the relationship between frailty syndrome (FS) and QoL in patients following acute coronary syndrome (ACS) non-ST elevation myocardial infarction (NSTEMI). Patients and Methods: The study involved 100 patients (61 men, 39 women, the average age: M ± SD =66.12±10.92 years). The study used standardized research tools: a questionnaire to assess QoL (World Health Organization Quality of Life Scale Brief …
Kuormituskoe modernin kuvantamisen aikakaudella
2019
Kuormituskoetta käytetään sepelvaltimotaudin ja muidenkin sydänsairauksien diagnosoinnissa, ennusteen arvioinnissa, hoidon suunnittelussa ja seurannassa. Kuormituskokeen keskeisin etu on sen helppo saatavuus sekä avoterveydenhuollossa että erikoissairaanhoidossa. Rasitukseen liittyvien oireiden tai suorituskyvyn heikkenemisen yhteydessä kuormituskoe on edelleen arvokas perustutkimus. Sen käytön keskeisin rajoite liittyy sen diagnostiseen osuvuuteen, ja sepelvaltimotaudin ali- ja ylidiagnostiikan välttämiseksi kuormituskokeen käyttö tulisikin rajata liikuntakykyisiin potilaisiin, joilla taudin todennäköisyys ennen testiä on keskisuuri tai suuri. Kuormituskoe sopii potilaille, joiden lepo-EKG…
Heart rate and other risk factors in outpatients with stable coronary artery disease in Latvia
2011
Heart rate and other risk factors in outpatients with stable coronary artery disease in Latvia The aim of the study was to characterise coronary artery disease (CAD) outpatients in Latvia by risk factors (RF) including heart rate (HR), physical examination data, clinical data and treatment. Twelve practitioners had each examined and questioned 6 to 12 patients with established CAD (n = 120). The most frequent cardiovascular (CV) RF and co-morbidity were dyslipidemia (94.2%) and hypertension (78.3%), respectively. Prevalence of increased resting HR (≥70 bpm) was 35.9% and 33.6%, when measured by pulse palpation and electrocardiography, respectively. Regarding other RFs, prevalence of treated…
Nitrate and nitrite in the diet: How to assess their benefit and risk for human health
2015
Nitrate is a natural constituent of the human diet and an approved food additive. It can be partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases blood pressure. This effect is associated with a reduced risk regarding cardiovascular disease, myocardial infarction, and stroke. Moreover, dietary nitrate has been associated with beneficial effects in patients with gastric ulcer, renal failure, or metabolic syndrome. Recent studies indicate that such beneficial health effects due to dietary nitrate may be achievable at intake levels resulting from the daily consumption of nitrate-rich vegetables. N-nitroso compounds are endogenously formed in humans. However…