Search results for "corpus"
showing 10 items of 698 documents
Physical activity predicts population-level age-related differences in frontal white matter
2018
AbstractPhysical activity has positive effects on brain health and cognitive function throughout the lifespan. Thus far, few studies have examined the effects of physical activity on white matter (WM) microstructure and psychomotor speed within the same, population-based sample (critical if conclusions are to extend to the wider population). Here, using diffusion tensor imaging and a simple reaction time task within a relatively large population-derived sample (N = 399; 18–87 years) from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), we demonstrate that physical activity mediates the effect of age on white matter integrity, measured with fractional anisotropy. Higher self-repor…
Transient hypothyroidism during lactation arrests myelination in the anterior commissure of rats. A magnetic resonance image and electron microscope …
2018
Thyroid hormone deficiency at early postnatal ages affects the cytoarchitecture and function of neocortical and telencephalic limbic areas, leading to impaired associative memory and in a wide spectrum of neurological and mental diseases. Neocortical areas project interhemispheric axons mostly through the corpus callosum and to a lesser extent through the anterior commissure (AC), while limbic areas mostly project through the AC and hippocampal commissures. Functional magnetic resonance data from children with late diagnosed congenital hypothyroidism and abnormal verbal memory processing, suggest altered ipsilateral and contralateral telencephalic connections. Gestational hypothyroidism aff…
Studies of the spontaneous motility and the effect of histamine on isolated myometrial strips of the nonpregnant human uterus: the influence of vario…
1990
We investigated the spontaneous uterine activity of isolated corpus uteri myometrial strips from 30 patients with nonpathologic myometrium, 26 patients with uterine myoma, 23 patients with uterine adenomyosis, and three patients with uterine malignancy. We also investigated the influence of these conditions on the response of the uterus to histamine. The results show the same qualitative cyclic changes of the spontaneous motility of isolated myometrial strips throughout the menstrual cycle in all the abnormalities studied. These changes are characterized by a low amplitude and high frequency of spontaneous contractions in the proliferative phase and lower frequency with higher amplitude of …
Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons
2009
Metabotropic glutamate (mGlu) receptors have been considered potential targets for the therapy of experimental parkinsonism. One hypothetical advantage associated with the use of mGlu receptor ligands is the lack of the adverse effects typically induced by ionotropic glutamate receptor antagonists, such as sedation, ataxia, and severe learning impairment. Low doses of the mGlu2/3 metabotropic glutamate receptor agonist, LY379268 (0.25-3 mg/kg, i.p.) increased glial cell line-derived neurotrophic factor (GDNF) mRNA and protein levels in the mouse brain, as assessed by in situ hybridization, real-time PCR, immunoblotting, and immunohistochemistry. This increase was prominent in the striatum, …
Neuroinflammatory and behavioral susceptibility profile of mice exposed to social stress towards cocaine effects.
2021
Using the social defeat (SD) model, numerous studies have shown that stressed mice display an enhanced response to the motivational effects of cocaine in the self-administration (SA) and conditioned-place preference (CPP) paradigms. However, not all subjects exposed to stress express its harmful effects. Some are particularly susceptible to the deleterious effects of repeated SD, while resilient mice successfully cope with stressful experiences and display adjusted psychological functioning after stress. Vulnerability to develop stress-related disorders, such as depression, has been linked to coping strategies and more recently to individual differences in the immune system. However, no stu…
Treading lightly on the Earth. Metaphorical frames in the discourse of ecotourism
2013
The present contribution aims to analyse the underlying metaphorical conceptualizations which frame the discourse of ecotourism and their similar or different surface realisations across languages and cultures (American English, British English and Italian). It addresses the issue of ideological categories construed by the discourse of ecotourism to promote its message in order to “persuade potential customers into becoming actual clients by addressing their cultural needs and personal motivations to travel” (Edwards and Curado 2003: 26). Ideology, in this work, relies on van Dijk’s (1998: 9) conceptualization as ‘social cognition’, namely a system of values, beliefs, thoughts shared by mem…
Théories françaises de la monnaie [Anthologie]
2016
Ensemble de textes rassemblés par les auteurs, précédé d'une introduction : "Genèse et évolution d’un corpus théorique", par Pierre Alary, Jérôme Blanc et Ludovic Desmedt; International audience; Ensemble de textes rassemblés par les auteurs, précédé d'une introduction : "Genèse et évolution d’un corpus théorique", par Pierre Alary, Jérôme Blanc et Ludovic Desmedt« La publication de cette anthologie répond à la volonté de rassembler et rendre disponibles certains textes importants de l’approche institutionnaliste de la monnaie telle qu’elle s’est développée en France depuis le début des années 1980. De nombreux auteurs ont œuvré dans ce sens, dans des écrits parus sur des supports variés (r…
Using Automatic Morphological Tools to Process Data from a Learner Corpus of Hungarian
2014
The aim of this article is to show how automatic morphological tools originally used to analyze native speaker data can be applied to process data from a learner corpus of Hungarian. We collected written data from 35 students majoring in Hungarian studies at the University of Zagreb, Croatia. The data were analyzed by magyarlanc, a sentence splitter, morphological analyzer, POS-tagger and dependency parser, which found 667 unknown word forms. We investigated the recommendations made by the Hungarian spellchecker hunspell for these unknown words and the correct forms were manually chosen. It was found that if the first suggestion made by hunspell was automatically accepted, an accuracy score…
Multi-word Clusters, Keywords and Key Terms in English Car Reviews: a Preliminary Corpus Linguistic Study
2018
Classroom use of authentic texts used in everyday communication has not always been an inseparable part of foreign language teaching. According to Grigaliuniene (2013, p. 17), “the structures many current textbooks teach for certain functions are either never used or used infrequently while quite unexpected structures are the ones that actually occur”. Despite the awareness of the importance of authentic patterns of language use, students often learn structures (lexical or grammatical) which are rarely used in actual communication. Teaching authentic phrases is even more important in English for Specific Purposes (ESP) where learners’ specific needs impact the design of a course (Dudley-Eva…
A Crowd-Sourced Database of Coronamusic: Documenting Online Making and Sharing of Music During the COVID-19 Pandemic
2021
When a sweeping COVID-19 pandemic forced cultural venues, schools, and social hangouts into hibernation in early 2020, music life relocated to the digital world. On social media platforms like YouTube, Facebook, Twitter, and TikTok, sofas and balconies took center stage for musical performances presented as live-streamed concerts and recorded videos. Amateurs and professional musicians alike embraced digital formats and innovated novel genres of corona-themed music. We will refer to the products of this musical phenomenon collectively as "coronamusic." Adapting a well-known term from cultural musicology (Small, 1999), the diverse practices of listening, playing, dancing, composing, rehearsi…