Search results for "cost"
showing 10 items of 5421 documents
Ricostruzione delle curve di durata mediante un nuovo approccio ecoidrologico
2012
Le curve di durata delle portate forniscono un importante sintesi dei processi idrologici più rilevanti occorrenti a scala di bacino. Sebbene vengano tipicamente ottenute a partire dalle osservazioni idrometriche, uno dei temi più rilevanti in idrologia è proprio la loro ricostruzione anche in bacini non strumentati. A tal proposito sono stati sviluppati negli ultimi anni svariati approcci teorici, alcuni dei quali meritano particolare attenzione per la loro semplicità di applicazione e accuratezza dei risultati mostrati. La curva di durata viene spesso disaggregata in due componenti: una componente veloce di deflusso superficiale ed una componente lenta di deflusso subsuperficiale. Un rece…
Incremental Delamination Processes under Cyclic Loading
2012
Roflumilast improves corticosteroid resistance COPD bronchial epithelial cells stimulated with toll like receptor 3 agonist
2015
Chronic obstructive pulmonary disease (COPD) is characterised by chronic pulmonary inflammation punctuated by periods of viral exacerbations. Recent evidence suggests that the combination of roflumilast with corticosteroids may improve the compromised anti-inflammatory properties of corticosteroids in COPD. We analyzed differential and combination anti-inflammatory effects of dexamethasone and roflumilast N-oxide in human bronchial epithelial cells (HBECs) stimulated with viral toll like receptor (TLR) agonists. Lung tissue and HBECs were isolated from healthy (n = 15), smokers (n = 12) and smokers with COPD (15). TLR3 expression was measured in lung tissue and in HBECs. IL-8 secretion was …
Effectiveness of BFRP confinement on the compressive behaviour of clay brick masonry cylinders
2020
Abstract This paper presents the results of an experimental and analytical study on the compressive behaviour of small clay brick masonry cylinders reinforced with a basalt fibre reinforced polymer (BFRP) composite. Fourteen cylinders, manufactured using two assembling schemes and confined using either one or two layers of BFRP grids, were tested under monotonic compression loading. Traditional strain measuring systems were integrated with digital image correlation (DIC) technique. The BFRP confined masonry cylinders showed a ductile behaviour characterised by a softening branch of the stress–strain curve. The experimental strains, strength, and full stress–strain curves were modelled using…
On the accuracy of the fast hierarchical DBEM for the analysis of static and dynamic crack problems
2010
In this paper the main features of a fast dual boundary element method based on the use of hierarchical matrices and iterative solvers are described and its effectiveness for fracture mechanics problems, both in the static and dynamic case, is demonstrated. The fast solver is built by representing the collocation matrix in hierarchical format and by using a preconditioned GMRES for the solution of the algebraic system. The preconditioner is computed in hierarchical format by LU decomposition of a coarse hierarchical representation of the collocation matrix. The method is applied to elastostatic problems and to elastodynamic cases represented in the Laplace transform domain. The application …
Manuale di istituzioni di diritto pubblico
2018
Il volume si articola in sette parti: la prima è su "Il diritto e lo Stato", la seconda su "La normazione", la terza sui "Diritti e doveri", la quarta sugli "Organi e momenti della democrazia parlamentare", la quinta sugli "Organi ausiliari e tutele giurisdizionali", la sesta sulle "Autonomie territoriali e pubbliche amministrazioni", l'ultima sulla "Giustizia costituzionale". L'appendice è dedicata a favorire l'organizzazione dello studio. La tavola sinottica del Manuale (parti, capitoli, pagine) può essere utilizzata per programmare i momenti di lettura, memorizzazione e ripetizione degli argomenti. Le parole chiave e i quesiti di autovalutazione possono servire a verificare come proceda …
The effects of glucocorticoids on thymidine kinase and nucleoside phosphotransferase during development of chicken embryo retina.
1983
AbstractThymidine kinase in chick embryo retina reaches its highest values on the 8–10th day of development, then declines reaching the lowest value at hatching. The rate of DNA synthesis essentially follows this activity while, in contrast, nucleoside phosphotransferase increases progressively during development. Glucocorticoids at 5 × 10−6M lower the level of thymidine kinase in isolated retinas of chick embryo. The most effective steroid was hydrocortisone. The effect was observed in retinas from 8–18-day-old chick embryo and, except on the 18th day, was always of the same magnitude. We suggest that a glucocorticoid can be the natural factor responsible for the marked fall in thymidine k…
Mucoadhesive Solid Lipid Microparticles (SLM) for sustained release of corticosteroids to the lungs
2016
Pulmonary delivery is the preferred route of drug administration in the treatment of many respiratory disease, such as asthma and chronic obstructive pulmonary disease (COPD). Over the years, several kinds of carriers have been studied for sustained release of corticosteroids and bronchodilators to the lungs. Solid Lipid Microparticles (SLM) due to their biocompatibility and size (3-5 µm) can reach the bronchial epithelium directly, circumvent first pass metabolism and avoid systemic toxicity [1,2]. In this work we describe the preparation and the characterization of two different systems subjected to chitosan and alginate coating for sustained release of fluticasone propionate (FP) into th…
Ecohydrology in Mediterranean areas: a numerical model to describe growing seasons out of phase with precipitations
2008
The probabilistic description of soil moisture dynamics is a relatively new topic in hydrology. The most common ecohydrological models start from a stochastic differential equation describing the soil water balance, where the unknown quantity, the soil moisture, depends both on spaces and time. Most of the solutions existing in literature are obtained in a probabilistic framework and under steady-state condition; even if this last condition allows the analytical handling of the problem, it has considerably simplified the same problem by subtracting generalities from it. <br><br> The steady-state hypothesis, appears perfectly applicable in arid and semiarid climatic areas like th…
Experimental characterization of dacron 360 woven constitutive behavior
2010
In the present paper some experimental analyses of Dacron© 360 woven aimed to characterize its constitutive behavior are presented. This woven, widely adopted in sail manufacturing, is obtained by weaving polyethylene terephthalate (PET) yarn and it shows some peculiar features due to the manufacturing process. The experimental tests, in terms of tensile tests and cyclic tests, clearly show the orthotropy features of the material, its high strength and deformability. Finally, the examination with optical microscope of the tested specimens allows to evidence how the warp and weft yarns interact.