Search results for "costa"

The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma

2014

Interleukin (IL)-31A binds to an heterodimer composed of IL-31 receptor A (IL-31RA) and Oncostatin M Receptor (OSMR). The IL-31/IL-31R complex is involved in the pathogenesis of various skin diseases, including cutaneous T-cell lymphoma. No information is available on the relations between the IL-31/IL-31R complex and B-cell lymphoma. Here we have addressed this issue in follicular lymphoma (FL), a prototypic germinal center(GC)-derived B-cell malignancy. IL-31 enhanced primary FL cell proliferation through IL-31R-driven signal transducer and activator of transcription factor 1/3 (STAT1/3), extracellular signal-regulated kinase 1/2 (ERK1/2) and Akt phosphorylation. In contrast, GC B cells d…

Comparison between MBR and MB-MBR pilot plants subject to a gradual salinity increase: analysis of biokinetic and fouling behaviour

2014

Two pilot plants were investigated for the treatment of wastewater subject to a gradual increase of salinity. In particular, a membrane bioreactor (MBR) and a moving bed biofilm membrane bioreactor (MB-MBR) were studied. Carbon and ammonium removal, kinetic constants and membranes fouling rates have been assessed. Both plants showed very high efficiency in terms of carbon and ammonium removal and the gradual salinity increase led to a good acclimation of the biomass, as confirmed by the respirometric tests. Significant biofilm detachments from carriers were experienced, which contributed to increase the irreversible superficial cake deposition. However, this aspect prevented the pore foulin…

Some like it cold: the glossiphoniid parasites of the Sicilian endemic pond turtle Emys trinacris (Testudines, Emydidae), an example of ‘parasite ine…

2016

The freshwater turtles of the genus Emys and some leech species of the family Glossiphoniidae are the only Palaearctic representatives of primarily Nearctic taxa, which jointly colonized Eurasia and the Maghreb during the Miocene. The strict trophic relationships occurring between the glossiphoniid parasite leech Placobdella costata and its host, the emydid Emys orbicularis, make them a prime example of host–parasite cophylogenetic evolution. In the light of the discovery of the Sicilian cryptic endemic species Emys trinacris, which is the sister species to the widespread Palaearctic E. orbicularis, the possible cophylogenetic divergence of the turtle hosts and their leech parasites was inv…

Correlation between Anthropometric and Ultrasound Measurement for Dry Needling of The Iliocostalis Lumborum Muscle with a Safety Protocol: A Cross-Se…

2022

Introduction: the management of musculoskeletal pain through the application of dry needling (DN) is effective. The application of this technique can carry very infrequent major risks on muscles, such as on the iliocostalis lumborum due to its proximity to the kidney and the peritoneum. It is important to establish a DN protocol based on the different anthropometric variables of the subjects. Main objective: the main objective of this study was to investigate the correlation between different anthropometric variables and the skin-kidney and skin-peritoneum distances to establish the size of the needle that could perform DN in the iliocostalis lumborum muscle without risk. Design: a cross-se…

in tema di rapporti fra l'illecita concorrenza con minaccia o violenza (art. 513-bis, c.p.) e la circostanza aggravante di cui all'art. 7 d.l. 152/19…

2011

Direct interaction of the Usher syndrome 1G protein SANS and myomegalin in the retina

2011

Contains fulltext : 96822.pdf (Publisher’s version ) (Closed access) The human Usher syndrome (USH) is the most frequent cause of combined hereditary deaf-blindness. USH is genetically heterogeneous with at least 11 chromosomal loci assigned to 3 clinical types, USH1-3. We have previously demonstrated that all USH1 and 2 proteins in the eye and the inner ear are organized into protein networks by scaffold proteins. This has contributed essentially to our current understanding of the function of USH proteins and explains why defects in proteins of different families cause very similar phenotypes. We have previously shown that the USH1G protein SANS (scaffold protein containing ankyrin repeat…

Biosilicification of loricate choanoflagellate: organic composition of the nanotubular siliceous costal strips of Stephanoeca diplocostata.

2010

SUMMARY Loricate choanoflagellates (unicellular, eukaryotic flagellates; phylum Choanozoa) synthesize a basket-like siliceous lorica reinforced by costal strips (diameter of approximately 100 nm and length of 3 μm). In the present study, the composition of these siliceous costal strips is described, using Stephanoeca diplocostata as a model. Analyses by energy-dispersive X-ray spectroscopy (EDX), coupled with transmission electron microscopy (TEM), indicate that the costal strips comprise inorganic and organic components. The organic, proteinaceous scaffold contained one major polypeptide of mass 14 kDa that reacted with wheat germ agglutinin. Polyclonal antibodies were raised that allowed …

[Cartas a Felipe II sobre fortificar los puertos]

Ms Títol pres del llom de l'enquadernació Al f. 2, s'inclou una taula de contingut Numeració antiga: 128 f. ; foliació posterior a llapis asignada pel catalogador: 248 f. ; fulls en blanc (129-228, 229v, 230r) Escrit per diverses mans i algunes anotacions marginals Filigrana Anotacions en el f. 1: "D[o]n Vespasiano Gonzaga, Principe de Sabioneta, Duque de Trageto fue Virrey de Valencia en 1575"; D[o]n Vespasiano Manrique Gonzaga, Conde de Paredes, fue Virrey de Val[enci]a en 1668, abuelo o visabuelo del C[on]de de Parcent actual" Cartes de Vespasiano Gonzaga Colonna, datades entre els anys 1570 i 1577, informant sobre les fortificacions i defenses en diferents llocs d'Espanya dirigides, la …

Lettera di Costantino al Senato con elogio del prefetto urbano, scheda epigrafica nr. 40 (CIL VI, 40776).

2013

Nonlinear Analysis of Phase-locked Loop-Based Circuits

2013

Main problems of simulation and mathematical modeling of high-frequency signals for analog Costas loop and for analog phase-locked loop (PLL) are considered. Two approachers which allow to solve these problems are considered. In the first approach, nonlinear models of classical PLL and classical Costas loop are considered. In the second approach, engineering solutions for this problems are described. Nonlinear differential equations are derived for both approaches.