Search results for "criteri"
showing 10 items of 807 documents
Stochastic Stability Analysis for Markovian Jump Neutral Nonlinear Systems
2012
In this paper, the stability problem is studied for a class of Markovian jump neutral nonlinear systems with time-varying delay. By Lyapunov-Krasovskii function approach, a novel mean-square exponential stability criterion is derived for the situations that the system's transition rates are completely accessible, partially accessible and non-accessible, respectively. Moreover, the developed stability criterion is extended to the systems with different bounded sector nonlinear constraints. Finally, some numerical examples are provided to illustrate the effectiveness of the proposed methods.
Robust Finite-Time Control of Switched Linear Systems and Application to a Class of Servomechanism Systems
2015
This paper investigates finite-time (FT) stability and stabilization problems for a class of switched linear systems with polytopic uncertainties. Both stable and unstable subsystems are considered to coexist in the system, and a new concept of extended FT stability is proposed as the first attempt. A stability criterion is first established, where the admissible maximum switching number is obtained while ensuring extended FT stability of switched linear systems with time-varying delays under a given maximum ratio between the running time of unstable subsystems and the running time of stable subsystems. Sufficient conditions on the existence of desired memory state-feedback controllers are …
Validating the early childhood classroom observation measure in first and third grade classrooms
2016
The present study reports on the psychometric properties of the Early Childhood Classroom Observation Measure (ECCOM) in Finnish and Estonian first and third grade classrooms. The observation data were collected from 91 first grade teachers and 70 third grade teachers. Teachers' curriculum goals, teaching experience and the classroom size were measured also. The results of confirmatory factor analysis provided evidence of the three-factor model (management, climate, and instruction) for each dimension—child-centred, teacher-directed, and child-dominated—in both grades. The reliability of the dimensions and sub-scales was good, and some evidence was also found for criterion validity. The fin…
Development of an MCDA framework for evaluation and positioning of oncological treatments in clinical practice.
2019
95 Background: Ensuring that effective innovations are accessible in a timely and affordable manner to all cancer patients is a challenge that stakeholders face today. Several oncology frameworks (ASCO, ESMO, ICER, NCCN) have been developed to define and quantify the value of oncological therapies to support clinicians and patients at the time of selection and as a basis for decision-making. However, current frameworks only define treatment value in terms of clinical benefit, creating a need for one that allows holistic evaluation of treatments and supports decision-making in clinical practice. The ECO Foundation led this study to develop a reflective multi-criteria decision analysis (MCDA…
Extended pancreas donor program – the EXPAND study rationale and study protocol
2013
Background Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or without impaired renal function. Unfortunately, transplant waiting lists for this indication are increasing because the current organ acceptability criteria are restrictive; morbidity and mortality significantly increase with time on the waitlist. Currently, only pancreas organs from donors younger than 50 years of age and with a body mass index (BMI) less than 30 are allocated for transplantation in the Eurotransplant (ET) area. To address this …
Bayesian versus data driven model selection for microarray data
2014
Clustering is one of the most well known activities in scientific investigation and the object of research in many disciplines, ranging from Statistics to Computer Science. In this beautiful area, one of the most difficult challenges is a particular instance of the model selection problem, i.e., the identification of the correct number of clusters in a dataset. In what follows, for ease of reference, we refer to that instance still as model selection. It is an important part of any statistical analysis. The techniques used for solving it are mainly either Bayesian or data-driven, and are both based on internal knowledge. That is, they use information obtained by processing the input data. A…
An interactive approach to multiple criteria optimization with multiple decision-makers
1986
In this article we propose a formal man-machine interactive approach to multiple criteria optimization with multiple decision makers. The approach is based on some of our earlier research findings in multiple criteria decision making. A discrete decision space is assumed. The same framework may readily be used for multiple criteria mathematical programming problems. To test the approach two experiments were conducted using undergraduate Business School students as subjects in Finland and in the United States. The context was, respectively, a high-level Finnish labor-management problem and the management-union collective bargaining game developed at the Krannert Graduate School of Management…
Sources and Boundaries of Institutional and Linguistic Normativity. Towards a Critical Social Ontology.
2013
Since Hegel and until speech acts theory and contemporary social ontology it came to full development the idea that most of reasons, duties, rights, entitlements, have to do, against Kant, with our participation to social, linguistic and institutional practices of the lifeform to which we belong rather than or more than with our dealing with “substantive moral principles”. But if we accept, with Hegel, that every individual rational determination of the will is justified as such only as a part of our collective Sittlichkheit (Hegel, 1967, cf. Di Lorenzo Ajello, 2009); if we accept from speech acts theory that there are commitments, rights and entitlements specific to every type of speech ac…
Molecular Classification of N-Aryloxazolidinone-5-carboxamides as Human Immunodeficiency Virus Protease Inhibitors
2015
Algorithms for classification and taxonomy are proposed in this chapter based information entropy (IE) and its production. The 38 N- aryloxazolidinone-5-carboxamides (NCAs), for human immunodeficiency virus (HIV) protease (PR) inhibition, are classified using seven characteristic chemical properties of different moieties: R 1/2 , R 3–6 on different phenyls and R 7 . Many classification algorithms are based on IE. When applying some procedures to moderate-sized sets, excessive number of results appear compatible with the data and suffer combinatorial explosion. However, after the equipartition conjecture (EC), one has a selection criterion among different variants that results from classifi…
Molecular Classification of 5-Amino-2-Aroylquinolines and 4-Aroyl-6,7,8-Trimethoxyquinolines as Highly Potent Tubulin Polymerization Inhibitors
2013
Algorithms for classification and taxonomy are proposed based on criteria as information entropy and its production. It is classified a series of 5-amino-2-aroylquinolines (AAQs) and 4-aroyl-6,7,8-trimethoxyquinolines (TMQs) combretastatin analogues for anti-cancer activity. 5-Amino-6-methoxy-2-aroylquinoline AAQ showed anti-proliferative activity more potent as compared to combretastatin A-4 (CA4), against various human cancer cell lines and a multidrug resistance (MDR) cancer cell line. On the basis of AAQ/TMQ structure–activity relationship new derivatives are designed. The AAQs/TMQs are classified using nine characteristic chemical properties in molecules. Many classification algorithms…