Search results for "cryoprotectant"

showing 4 items of 14 documents

A way to follow the viability of encapsulated Bifidobacterium bifidum subjected to a freeze-drying process in order to target the colon: Interest of …

2012

The aim of this work was to apply flow cytometry in order to assess and compare the viability of freeze-dried entrapped bacteria with an usual technique by quantification by plate count techniques. It also aimed at studying the effect of various cryoprotectants on the viability of an entrapped Bifidobacterium bifidum subjected to freeze-drying to check their ability to be delivered all along the gastro-intestinal tract. The alginate-pectinate beads were chosen as the encapsulation matrix added with different protectants. The beads were characterized by scanning electron microscopy and the viability was checked by both methods. The best combination to improve viability of entrapped bacteria …

Sodium ascorbateCryoprotectantAlginatesColonved/biology.organism_classification_rank.speciesPharmaceutical ScienceFlow cytometryFreeze-dryingchemistry.chemical_compoundCryoprotective AgentsGlucuronic AcidmedicineGlycerolViability assayBifidobacteriumMicrobial ViabilityBifidobacterium bifidumChromatographybiologymedicine.diagnostic_testved/biologyHexuronic AcidsFlow Cytometrybiology.organism_classificationMolecular biologyBacterial LoadFreeze DryingchemistryPectinsBifidobacteriumEuropean Journal of Pharmaceutical Sciences
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Osmotic and cryoprotective effects of a mixture of DMSO and ethylene glycol on rabbit morulae.

1993

Abstract Comparisons were made of the osmotic and cryoprotective effects on rabbit embryos preserved by vitrification with 2 solutions and by conventional freezing. Embryos obtained from rabbits killed 70 to 72 h after mating were used in the study (n = 948). Initially, toxicity of the 3 cryoprotectants was studied in fresh (unfrozen) embryos (n = 135). Subsequently, embryos placed in ethylene glycol (EG, 40% v/v; n = 88) and ethylene glycol with dimethyl sulfoxide (EG+DMSO, 20% v/v each, respectively; n = 344) were loaded into straws and plunged directly into liquid nitrogen. Embryos placed in 1.5 M DMSO and 20% heat inactivated rabbit serum were subjected to conventional freezing in a pro…

animal structuresCryoprotectantEquineDimethyl sulfoxideLiquid nitrogenBiologyCryopreservationAndrologychemistry.chemical_compoundmedicine.anatomical_structureFood AnimalsBiochemistrychemistryEmbryo cryopreservationembryonic structuresmedicineAnimal Science and ZoologyVitrificationBlastocystSmall AnimalsEthylene glycolTheriogenology
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Chemical Characteristics and Viability of Starter Cultures of Freeze–Dried Sweet Potato Extract–Supplemented Synbiotic Yogurt

2021

The research aimed to determine the sucrose concentration as a cryoprotectant to obtain the chemical properties and the viability of Lactic Acid Bacteria (LAB) and Lactobasillus plantarum in the synbiotic yogurt. It adopted a one–factor Completely Randomized Design (CRD) by including sucrose in concentrations from 0 %, 2.5 %, 5 % to 7.5 %, three replications. The results showed various sucrose concentrations significantly affected the yields of the purple sweet potato extract– supplemented synbiotic yogurt, reduction–sugar level, the total of LAB, and the total of L. plantarum before and after the freeze–drying process, no significant impact on the moisture content and total quantity of LAB…

free radicallcsh:GE1-3500303 health sciencesSucroseCryoprotectantbiologyfermented drink030306 microbiologyfood and beverageshealthy consumptionbiology.organism_classificationLactic acidfunctional food03 medical and health scienceschemistry.chemical_compoundsucrose as cryoprotectantStarterFunctional foodchemistryFood scienceWater contentBacteriaCompletely randomized designlcsh:Environmental sciences030304 developmental biologyE3S Web of Conferences
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Viability and function of the cryopreserved whole rat ovary: comparison between slow-freezing and vitrification

2011

Objective To investigate four different protocols for cryopreservation of the whole rat ovary with intact vasculature to evaluate whether differences exist in post-thawing viability of the ovary after either vitrification or slow freezing. Design Experimental study. Setting Obstetrics and gynecology department. Animal(s) Immature Sprague-Dawley female rats. Intervention(s) Ovaries were isolated with the vascular tree intact up to the bifurcation of the abdominal aorta and were subsequently cannulated. The ovaries were flushed with increasing concentrations of the cryoprotectant dimethyl sulfoxide (DMSO) to either 1.5 or 7 M. The ovaries underwent cryopreservation by vitrification or passive…

medicine.medical_specialtyNeutral redTime FactorsCryoprotectantApoptosisOvaryBiologyCryopreservationRats Sprague-DawleyTissue Culture TechniquesAndrologychemistry.chemical_compoundCryoprotective AgentsOvarian FollicleFreezingFollicular phasemedicineAnimalsDimethyl SulfoxideVitrificationIncubationCryopreservationTissue SurvivalGynecologyDose-Response Relationship DrugEstradiolCaspase 3Dimethyl sulfoxideOvaryFertility PreservationObstetrics and GynecologyOrgan PreservationImmunohistochemistryVitrificationRatsPerfusionmedicine.anatomical_structureReproductive MedicinechemistryFemaleFertility and Sterility
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