Search results for "cycle"

showing 10 items of 3119 documents

α,β-Dehydroamino acids in naturally occurring peptides

2014

α,β-Dehydroamino acids are naturally occurring non-coded amino acids, found primarily in peptides. The review focuses on the type of α,β-dehydroamino acids, the structure of dehydropeptides, the source of their origin and bioactivity. Dehydropeptides are isolated primarily from bacteria and less often from fungi, marine invertebrates or even higher plants. They reveal mainly antibiotic, antifungal, antitumour, and phytotoxic activity. More than 60 different structures were classified, which often cover broad families of peptides. 37 different structural units containing the α,β-dehydroamino acid residues were shown including various side chains, Z and E isomers, and main modifications: meth…

Dehydroamino acidsStereochemistryClinical BiochemistryPeptideReview ArticleHeterocyclesBiochemistryMethylationResidue (chemistry)IsomerismDepsipeptidesSide chainPeptide bondAmino AcidsDepsipeptidechemistry.chemical_classificationNatural productsbiologyChemistryDehydropeptidesOrganic ChemistryBiological activitybiology.organism_classificationAmino acidBiochemistryZ/E isomerisationPeptidesBacteriaAmino Acids
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Stable isotope profiles of nitrogen gas indicate denitrification in oxygen-stratified humic lakes

2011

Mid-summer N(2) profiles were analyzed from nine oxygen-stratified, humic-acid-rich lakes using a continuous flow isotope ratio mass spectrometer and a Gasbench II device. Sample preparation steps were performed under water to avoid air contamination. The instrument precision for the δ(15)N measurement was high (0.03‰), but for the whole sampling and analysis procedure the mean deviation between replicate samples was 0.13‰ for the δ(15)N measurements and 5.5% for the N(2) gas concentration analysis. The results show that the Gasbench peripheral was suitable for measurement of the (15)N natural abundance of dissolved nitrogen gas, with denitrification indicated by the oversaturation and slig…

Denitrification010504 meteorology & atmospheric sciencesIsotopeChemistryStable isotope ratio010401 analytical chemistryOrganic Chemistrychemistry.chemical_element01 natural sciencesNitrogen6. Clean waterIsotopes of nitrogen0104 chemical sciencesAnalytical ChemistryAnammoxTRACEREnvironmental chemistryNitrogen cycleSpectroscopy0105 earth and related environmental sciencesRapid Communications in Mass Spectrometry
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N2O and NO emissions by agricultural soils with low hydraulic potentials

2002

N2O and NO production were studied on five agricultural soils with low hydraulic potentials. All experiments were performed in a laboratory under standard incubation conditions to limit any intrinsic soil heterogeneity. The mechanisms involved in NO and N2O production was investigated using the inhibitory properties of acetylene on nitrification and N2O reduction. This work confirmed that N2O and NO could be produced by soils under aerobic conditions. Nitrification seemed to be the only process involved in NO production and the main process involved in N2O production by the five studied soils when the water content was low. Nevertheless, aerobic denitrification with N2O release was observed…

DenitrificationChemistrySoil ScienceCalcisol[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil studyMicrobiologyHydraulic conductivityAerobic denitrificationEnvironmental chemistrySoil waterNitrification[SDV.SA.SDS] Life Sciences [q-bio]/Agricultural sciences/Soil studyWater contentNitrogen cycleSoil Biology and Biochemistry
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Inhibitory capacities of acetylene on nitrification in two agricultural soils

2000

Abstract Acetylene is currently used to distinguish between the relative contribution of nitrification and denitrification to soil emissions of the greenhouse gas, N 2 O. The basis of this method is that acetylene at low partial pressures inhibits nitrification without affecting N 2 O reduction. This paper reports experiments where low acetylene partial pressures were insufficient to totally inhibit nitrification in an hypercalcareous rendosol at water potentials higher than −3.5 MPa while they were always sufficient in a redoxic luvisol.

DenitrificationChemistrySoil Sciencechemistry.chemical_elementNitrous oxide[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil studyMicrobiologyNitrogenchemistry.chemical_compoundWater potentialAgronomyAcetyleneEnvironmental chemistrySoil waterNitrification[SDV.SA.SDS] Life Sciences [q-bio]/Agricultural sciences/Soil studyNitrogen cycle
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Insights into the effect of soil pH on N(2)O and N(2) emissions and denitrifier community size and activity.

2010

ABSTRACT The objective of this study was to investigate how changes in soil pH affect the N 2 O and N 2 emissions, denitrification activity, and size of a denitrifier community. We established a field experiment, situated in a grassland area, which consisted of three treatments which were repeatedly amended with a KOH solution (alkaline soil), an H 2 SO 4 solution (acidic soil), or water (natural pH soil) over 10 months. At the site, we determined field N 2 O and N 2 emissions using the 15 N gas flux method and collected soil samples for the measurement of potential denitrification activity and quantification of the size of the denitrifying community by quantitative PCR of the narG , napA ,…

DenitrificationSoil testNitrogenNitrous OxideNITROUS-OXIDE EMISSIONSDINITROGENNITRIFICATIONApplied Microbiology and BiotechnologyDNA RibosomalMicrobial EcologyDenitrifying bacteriaSoilSoil pHRNA Ribosomal 16SNitrogen cycleNitritesSoil Microbiology[SDV.EE]Life Sciences [q-bio]/Ecology environmentEcologyNitrogen IsotopesChemistrySoil classificationBiodiversityHydrogen-Ion ConcentrationAgronomySoil waterMetagenomeABUNDANCESoil microbiologyNITRATEFood ScienceBiotechnologyApplied and environmental microbiology
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Characterization of denitrification gene clusters of soil bacteria via a metagenomic approach

2009

International audience; Denitrification is a microbial respiratory process contributing to the emission of greenhouse gas. The study of denitrifying bacteria, like that of others, is hindered by characteristics that can prevent up to 99% of soil bacteria from being cultivated in vitro. New approaches based on the direct extraction of DNA from the natural environment and PCR amplifications can overcome limitations due to bacterial unculturability, but until now their application to denitrification genes has led only to the recovery of partial sequences for some of these genes.Our goals in this study were to apply a metagenomic approach characterized by cloning of DNA extracted from soil and …

Denitrification[SDV]Life Sciences [q-bio]Microbial metabolismNIRKApplied Microbiology and Biotechnology[ SPI.NRJ ] Engineering Sciences [physics]/Electric powerGene OrderGene clusterPHYLOGENETIC ANALYSISNITROUS-OXIDE REDUCTASESoil MicrobiologyComputingMilieux_MISCELLANEOUS2. Zero hunger0303 health sciencesdenitrificationEcologyfood and beveragesFAMILYCOMMUNITYPCRMultigene Family[SDE]Environmental SciencesSoil microbiologyMetabolic Networks and PathwaysBiotechnologyDNA BacterialDOMAINSNitrogenMolecular Sequence DataComputational biologyBiologyMicrobial Ecologysoil03 medical and health sciencesmetagenomic;n-cycle;denitrification;soil Bacterial ProteinsOperonBotanymetagenomicNitrogen cycle030304 developmental biology[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyNITRIC-OXIDEBacteriaSequence Homology Amino Acid030306 microbiology[SPI.NRJ]Engineering Sciences [physics]/Electric powerSequence Analysis DNAn-cyclebiology.organism_classificationDENITRIFYING PSEUDOMONAS-STUTZERIMetagenomicsPyrosequencing[SDE.BE]Environmental Sciences/Biodiversity and EcologyBacteria[SPI.NRJ] Engineering Sciences [physics]/Electric powerFood ScienceNOSZ GENES
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Ecology of Denitrifying Prokaryotes in Agricultural Soil

2007

Denitrification is a microbial respiratory process during which soluble nitrogen oxides are used as an alternative electron acceptor when oxygen is limiting. It results in considerable loss of nitrogen, which is the most limiting nutrient for crop production in agriculture. Denitrification is also of environmental concern, since it is the main biological process responsible for emissions of nitrous oxide, one of the six greenhouse gases considered by the Kyoto protocol. In addition to natural variations, agroecosystems are characterized by the use of numerous practices, such as fertilization and pesticide application, which can influence denitrification rates. This has been widely documente…

Denitrifying bacteriaDenitrificationEcologyAgriculturebusiness.industryGreenhouse gasPesticide applicationEnvironmental scienceKyoto ProtocolArable landbusinessHuman impact on the nitrogen cycle
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Cytotoxic Activity of Organotin(IV) Derivatives with Triazolopyrimidine Containing Exocyclic Oxygen Atoms

2020

In this study cytotoxicity of organotin(IV) compounds with 1,2,4-triazolo[1,5-a]pyrimidines, Me3Sn(5tpO) (1), n-Bu3Sn(5tpO) (2), Me3Sn(mtpO) (3), n-Bu3Sn(mtpO) (4), n-Bu3Sn(HtpO2) (5), Ph3Sn(HtpO2) (6) where 5HtpO = 4,5-dihydro-5-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine, HmtpO = 4,7-dihydro-5-methyl-7-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine, and H2tpO2 = 4,5,6,7-tetrahydro-5,7- dioxo-[1,2,4]triazolo-[1,5-a]-pyrimidine, was assessed on three different human tumor cell lines: HCT-116 (colorectal carcinoma), HepG2 (hepatocarcinoma) and MCF-7 (breast cancer). While 1 and 3 were inactive, compounds 2, 4, 5 and 6 inhibited the growth of the three tumor cell lines with IC50 values in the submicromolar …

DenticityCellPharmaceutical Science01 natural sciencesAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryOrganotin CompoundstriazolopyrimidineCytotoxicityMembrane Potential MitochondrialCytotoxinsapoptosisBiological activityHep G2 CellsG2 Phase Cell Cycle CheckpointsGene Expression Regulation Neoplasticmedicine.anatomical_structureChemistry (miscellaneous)Mitochondrial MembranesMCF-7 CellsMolecular MedicineCyclin-Dependent Kinase Inhibitor p21crystal structurein vitro anticancer activityPyrimidineCell SurvivalStereochemistryorganotin(iv)010402 general chemistryArticlelcsh:QD241-441Inhibitory Concentration 50Structure-Activity Relationshiplcsh:Organic chemistrymedicineHumansPhysical and Theoretical ChemistryMetallodrug010405 organic chemistryLigandOrganic ChemistryTriazolesHCT116 CellsapoptosiG1 Phase Cell Cycle Checkpoints0104 chemical sciencesPyrimidineschemistrymetallodrugsCell cultureApoptosisDrug DesignTumor Suppressor Protein p53Reactive Oxygen SpeciesMolecules
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Synthesis of orthometallated rhodium(III) compounds. Crystal structures of [RhCl2{η2(C6H4)PPh2}(η2-dppm)] and [RhCl{η2(C6H4)PPh2}(η1-PCCl)(phen)] (…

1993

Abstract Neutral and cationic rhodium(III) metallated compounds containing a four-membered ring are prepared by different synthetic methods: (i) from rhodium(I) compounds that contain the ligand P( o -ClC 6 H 4 )PPh 2 , by 2c-2e intramolecular oxidative addition; (ii) from metallated dirhodium(II) compounds; (iii) by ligand substitution in [RhCl 2 {η 2 -(C 6 H 4 )PPh 2 }{η 2 -P( o -ClC 6 H 4 )Ph 2 }]. The crystal structures of [RhCl 2 {η 2 -(C 6 H 4 )PPh 2 }(η 2 -dppm)] ( 2 ) and of the dichloromethane solvate of [RhCl{η 2 -(C 6 H 4 )PPh 2 }{η 1 -P( o -ClC 6 H 4 )Ph 2 }(phen)](SbF 6 ) ( 11 ) have been determined by X-ray diffraction methods. In both complexes the Rh atom is in the distorted…

DenticityChemistryLigandStereochemistryPhenanthrolinechemistry.chemical_elementCrystal structureMetallacycleMedicinal chemistryOxidative additionRhodiumInorganic Chemistrychemistry.chemical_compoundMaterials ChemistryPhysical and Theoretical ChemistryPhosphineInorganica Chimica Acta
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Fluorinated Heterocyclic Compounds− The First Example of an Irreversible Ring-Degenerate Rearrangement on Five-Membered Heterocycles by Attack of an …

2004

The reactions of 5-perfluoroalkyl-1,2,4-oxadiazoles 3 with hydroxylamine in DMF give the regioisomeric 3-perfluoroalkyl-1,2,4-oxadiazoles 4 in excellent yields. This process is the first example of ring-degenerate rearrangement (RDR) occurring on five-membered heterocycles by attack of an external bidentate nucleophile, which replaces two heteroatoms of the ring. We suggest that an ANRORC-like mechanism occurs in which the addition of the nucleophilic nitrogen atom (NH2OH) on the C(5) atom of 3 is followed by ring opening and irreversible ring-degenerate closure by attack of the nucleophilic oxygen atom (=NOH) on the C(3) atom of the original ring, realizing an elegant and efficient synthes…

DenticityStereochemistryrearrangementOrganic ChemistryHeteroatomDegenerate energy levelsAtom (order theory)General MedicineRing (chemistry)Medicinal chemistrychemistry.chemical_compoundHydroxylaminechemistryNucleophilering-ring interconversionNucleophilic substitutionAb initio computationsnucleophilic substitutionPhysical and Theoretical ChemistryheterocycleEuropean Journal of Organic Chemistry
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