Search results for "cycle"

Echovirus 1 Endocytosis into Caveosomes Requires Lipid Rafts, Dynamin II, and Signaling EventsV⃞

2004

Binding of echovirus 1 (EV1, a nonenveloped RNA virus) to the α2β1 integrin on the cell surface is followed by endocytic internalization of the virus together with the receptor. Here, video-enhanced live microscopy revealed the rapid uptake of fluorescently labeled EV1 into mobile, intracellular structures, positive for green fluorescent protein-tagged caveolin-1. Partial colocalization of EV1 with SV40 (SV40) and cholera toxin, known to traffic via caveosomes, demonstrated that the vesicles were caveosomes. The initiation of EV1 infection was dependent on dynamin II, cholesterol, and protein phosphorylation events. Brefeldin A, a drug that prevents SV40 transport, blocked the EV1 infection…

Stress path dependence of hydromechanical behaviour of compacted scaly clay in wetting and drying suction controlled oedometer tests at constant vert…

2008

The results are presented of an experimental programme devoted to investigating the volumetric strain and water ratio (volume of water to volume of solids) evolution of a compacted scaly clay stressed by wetting and drying cycles in suction-controlled oedometer tests. The stress paths applied included loading and unloading cycles at constant matric suction and suction controlled wetting-drying cycles at constant vertical net stress. The test results show that during wetting and drying cycles the samples experienced irreversible shrinkage or swelling strains depending on the stress path applied. Irreversible water ratio increases were always observed in these cycles. However, a quasi-reversi…

Volume change behaviour of a compacted scaly clay during cyclic suction changes

2010

The research presented in this paper focuses on the investigation and modelling of the volume change response of compacted tectonised clay samples subjected to several wetting and drying cycles in controlled-suction oedometers. Oedometer tests were carried out under different values of constant vertical net stress, and wetting and drying cycles were performed varying applied matric suction between 10 and 800 kPa. The investigation was complemented with a study of the material microstructure to support the interpretation of the overall mechanical response. At a microscopic level, the material is characterized by different types of particle assemblages, scales, and clay aggregates. One of th…

Photocontrolled On-Surface Pseudorotaxane Formation with Well-Ordered Macrocycle Multilayers.

2016

The photoinduced pseudorotaxane formation between a photoresponsive axle and a tetralactam macrocycle was investigated in solution and on glass surfaces with immobilized multilayers of macrocycles. In the course of this reaction, a novel photoswitchable binding station with azobenzene as the photoswitchable unit and diketopiperazine as the binding station was synthesized and studied by NMR and UV/Vis spectroscopy. Glass surfaces have been functionalized with pyridine-terminated SAMs and subsequently with multilayers of macrocycles through layer-by-layer self assembly. A preferred orientation of the macrocycles could be confirmed by NEXAFS spectroscopy. The photocontrolled deposition of the …

Les coûts unitaires des formations scientifiques à bac + 5

1992

Design of the seismic retrofit of a school in accordance to a life cycle thinking approach

2018

UN APPROCCIO BASATO SULLA MODELLAZIONE 3D E IL LIFE CYCLE ASSESSMENT PER UNA GESTIONE SOSTENIBILE DELLA MANUTENZIONE STRADALE

2021

Among several goals of the road agencies, one of the most relevant is the maintenance and rehabilitation of the road pavement. The growth of traffic, the longstanding lack of funding and, sometimes, an emergency-based planning of intervention, are common drivers leading to low level of pavement conditions in terms of ride quality and safety. In addition both cost and environmental concerns due to monitoring stage are relevant issues within the management system of local and urban road network, especially. With the purpose of implementing sustainability in the road pavement management, this paper provides an approach based on coupled low- cost 3D image modelling distress identification and L…

Life Cycle Management delle pavimentazioni stradali

2022

Ormai parola chiave della nostra società, la sostenibilità è al centro di ricerche e dibattiti. La comunità scientifica si impegna da anni nella definizione di strumenti e metodologie comuni per riuscire a quantificarla, proponendo standard e linee guida basate sull’analisi del ciclo di vita, come il Life Cycle Assessment (LCA), di prodotti e processi. Nell’ambito dell’ingegneria civile esistono procedure standardizzate a livello internazionale per svolgere esercizi di Sustainability Assessment; queste risultano ben strutturate per gli edifici, meno dettagliate invece per altre opere, come le pavimentazioni stradali. Questo lavoro presenta il risultato principale del progetto “PavementLCM”,…

The Role of Fire in Achieving the Sustainable Development Goals of the United Nations

2019

The Sustainable Development Goals (SDGs) of the United Nations do not mention Fire as a key factor in achieving an environmentally-friendly human society. This paper reviews the key aspects of the impact of fire that make it necessary to update the SDGs. Upon reviewing the scientific literature, it was found that fire has been part of the Earth System for the last 400 million years, and that it is part of biogeochemical cycles. From a geological perspective, fire shaped the current Earth System. Humans have used fire in the last million years as hunter-gatherers, and the last Pleistocene period evolved with the presence of fire. Since the Neolithic revolution, humankind spread the use of fi…

Transportation and sustainable development in a mid-size French city, Dijon

2011

International audience