Search results for "cycle"
showing 10 items of 3119 documents
Guidelines for biomarker discovery in endometrium: correcting for menstrual cycle bias reveals new genes associated with uterine disorders
2021
Abstract Transcriptomic approaches are increasingly used in reproductive medicine to identify candidate endometrial biomarkers. However, it is known that endometrial progression in the molecular biology of the menstrual cycle is a main factor that could affect the discovery of disorder-related genes. Therefore, the aim of this study was to systematically review current practices for considering the menstrual cycle effect and to demonstrate its bias in the identification of potential biomarkers. From the 35 studies meeting the criteria, 31.43% did not register the menstrual cycle phase. We analysed the menstrual cycle effect in 11 papers (including 12 studies) from Gene Expression Omnibus: t…
A Simplified LCA Tool for Solar Heating and Cooling Systems
2016
Abstract This paper presents a user-friendly Life Cycle Assessment tool, which aims to support researchers, designers and decision-makers in evaluating the life cycle energy and environmental advantages related to the use of solar heating and cooling (SHC) systems in substitution of conventional ones, considering specific climatic conditions and building loads. The tool was developed within the Task 48 “Quality Assurance & Support Measures for Solar Cooling Systems”, promoted by the International Energy Agency in the framework of the SHC Programme.
Review on Life Cycle Assessment of Solar Photovoltaic Panels
2020
The photovoltaic (PV) sector has undergone both major expansion and evolution over the last decades, and currently, the technologies already marketed or still in the laboratory/research phase are numerous and very different. Likewise, in order to assess the energy and environmental impacts of these devices, life cycle assessment (LCA) studies related to these systems are always increasing. The objective of this paper is to summarize and update the current literature of LCA applied to different types of grid-connected PV, as well as to critically analyze the results related to energy and environmental impacts generated during the life cycle of PV technologies, from 1st generation (traditiona…
1H, 13C and 15N NMR chemical shift assignments of cAMP-regulated phosphoprotein-19 and -16 (ARPP-19 and ARPP-16)
2020
Protein Phosphatase 2A, PP2A, the principal Serine/threonine phosphatase, has major roles in broad range of signaling pathways that include regulation of cell cycle, cell proliferation and neuronal signaling. The loss of function of PP2A is linked with many human diseases, like cancer and neurodegenerative disorders. Protein phosphatase 2A (PP2A) functions as tumor suppressor and its tumor suppressor activity is inhibited by the overexpression of PP2A inhibitor proteins in most of the cancers. ARPP-19/ARPP-16 has been identified as one of the potential PP2A inhibitor proteins. Here, we report the resonance assignment of backbone 1H, 13C and 15N atoms of human ARPP-19 and ARPP-16 proteins. T…
Energy and environmental assessment of retrofit actions on a residential building
2014
Energy and environmental performances of buildings strictly depend on many factors related to the choice of construction materials, technical equipment, installation and use. In the following chapter a set of retrofit actions to improve the thermal performance of an existing conventional building is presented. The energy and environmental assessment of these actions is carried out following a life cycle approach. The embodied energy and the environmental impacts arisen from the production, transportation and installation phases of the required materials and components are calculated. Further, energy saving and environmental benefits and drawbacks concerning the assessed retrofit actions are…
Increasing the Circularity of asphalt mixtures: Integrated Sustainability and Circularity Assessment as a progress monitoring tool towards more Circu…
2021
Sustainability and Circular Economy (CE) are two concepts that lately have been profoundly linked to each other. The road engineering industry has gradually been adapting practices that are considered both circular and sustainable. However, not all of these practices entirely consider the whole life environmental and circularity assessment and implications of asphalt mixtures.; which in turn leads to doubtfully circular and sustainable approaches. For this reason in this thesis, after analysing the ways that National Road Authorities implement and communicate CE through questionnaires and web searches, a Material Circularity Index quantifying framework, based on the proposed methodology of …
Genetic diversity in the wild : cyclic population dynamics and population isolation
2013
Estradiol deficiency and skeletal muscle apoptosis: Possible contribution of microRNAs.
2020
Background Menopause leads to estradiol (E2) deficiency that is associated with decreases in muscle mass and strength. Here we studied the effect of E2 deficiency on miR-signaling that targets apoptotic pathways. Methods C57BL6 mice were divided into control (normal estrous cycle, n = 8), OVX (E2 deficiency, n = 7) and OVX + E2 groups (E2-pellet, n = 4). Six weeks following the OVX surgery, mice were sacrificed and RNA isolated from gastrocnemius muscles. miR-profiles were studied with Next-generation sequencing (NGS) and candidate miRs verified using qPCR. The target proteins of the miRs were found using in silico analysis and measured at mRNA (qPCR) and protein levels (Western blot). Resu…
Influence of Oral Contraceptive Use on Adaptations to Resistance Training
2019
Introduction: The majority of young women use oral contraceptives (OCs). Use of OCs has been associated with lower myofibrillar protein and tendon collagen synthesis rates, but it is unknown whether OCs will limit the adaptive response of myotendinous tissue to resistance training. Design and Methods: Fourteen healthy untrained young regular OC users (24 +/- 1 years, fat% 32 +/- 1, 35 +/- 2 ml.min(-1).kg(-1)) and 14 NOC users (non-OC, controls) (24 +/- 1 years, fat% 32 +/- 2, 34 +/- 2 ml.min(-1).kg(-1)) performed a 10-week supervised lower extremity progressive resistance training program. Before and after the intervention biopsies from the vastus lateralis muscle and the patellar tendon we…
La valutazione degli alunni nel primo ciclo dell’istruzione
2022
It describes the procedural process for replacing grades with descriptive judgments in the assessment of the learning objectives of primary school pupils starting from the academic year. 2020-21. This process is compared with the one followed between 1989 and 1993 for the introduction of assessments in middle school. It is believed that project-based institutional action research is the best way to introduce an innovation into the school system. It describes the procedural process for replacing grades with descriptive judgments in the assessment of the learning objectives of primary school pupils starting from the academic year. 2020-21. This process is compared with the one followed betwee…