Search results for "cycles"
showing 10 items of 306 documents
Identification of the essential protein domains for Mib2 function during the development of the Drosophila larval musculature and adult flight muscles
2016
The proper differentiation and maintenance of myofibers is fundamental to a functional musculature. Disruption of numerous mostly structural factors leads to perturbations of these processes. Among the limited number of known regulatory factors for these processes is Mind bomb2 (Mib2), a muscle-associated E3 ubiquitin ligase, which was previously established to be required for maintaining the integrity of larval muscles. In this study, we have examined the mechanistic aspects of Mib2 function by performing a detailed functional dissection of the Mib2 protein. We show that the ankyrin repeats, in its entirety, and the hitherto uncharacterized Mib-specific domains (MIB), are important for the…
CO2LD: An innovation educational project for High Degree Professional Training in Refrigeration
2013
EN] Refrigeration is one of the technology sectors that has sufered the most changes in the last twenty years, because of the negative impact of the fuids used in the refrigeration cycles, i.e., refrigerants, due to their impact on the ozone layer and their contribution to global warming. As a result of their negative efects, the European Union has established several directives to restrict the use of refrigerant fuids, and the sector therefore needs to adapt to the new regulations. This process of adaptation of the refrigeration sector to the new regulations must be carried out by all the agents involved, including those engaged in the training and education of the future refrigeration tec…
Advanced refrigerating plants based on transcritical cycles working with carbon dioxide for commercial refrigeration
2012
Supermarkets and hypermarkets require a huge amount of energy to maintain chilled and frozen food in product display cases and cold storage rooms and thermal comfort in the whole building. Systems exploited require very large refrigerant charges for operation and suffer significant leakages. The challenge for advanced systems, based on equipment which reduce TEWI, suggests the proposal of carbon dioxide: a natural working fluid. This paper deals with a feasibility study of a refrigerating system for a big hypermarket in Sicily based on a three-stage transcritical cycle working with carbon dioxide which is compared with an alternative system composed of two cycles operating as a binary refri…
Test cycles for the characterization of electrical drives devoted to wheelchair applications
2003
Today electrical wheelchairs are giving valuable increase of the quality of life of disabled people in developed countries. Despite the increasing diffusion of such an aid tool, specific standards for the characterization of their electric drives are not so developed as those available for urban electric vehicles. This paper presents a proposal for the test characterization of a wheelchair drive by means of test cycles with fixed speed trajectories. To this aim, the method, which is well known in the field of automobiles, has been purposely adapted and the obtained simulation results are satisfactory.
The predatory role of white shrimp (Litopenaeus setiferus) in seasonal declines of subtidal macrobenthos
2009
The overall purpose of this study was to develop a quantitative model to assess the influence of L. setiferus predation on subtidal macrobenthic abundance cycles in an estuarine creek system. Subtidal macrobenthic populations in temperate marine soft-bottom environments are known to undergo seasonal abundance cycles. Although the factors responsible for driving these seasonal shifts in abundance are difficult to identify, both environmental and biological factors have received credit. Juvenile white shrimp (Litopenaeus setiferus) are seasonally abundant epibenthic predators in the North Inlet estuary that have significant influence upon estuarine macrobenthic densities. Data generated from …
The role of crystalline, mobile amorphous and rigid amorphous fractions in the performance of recycled poly (ethylene terephthalate) (PET)
2012
[EN] The action of thermo-mechanical degradation induced by mechanical recycling of poly(ethylene terephthalate) was simulated by successive injection moulding cycles. Degradation reactions provoked chain scissions and a reduction in molar mass mainly driven by the reduction of diethyleneglycol to ethylene glycol units in the flexible domain of the PET backbone, and the formation of -OH terminated species with shorter chain length. The consequent microstructural changes were quantified taking into account a three-fraction model involving crystalline, mobile amorphous (MAF) and rigid amorphous fractions (RAF). A remarkable increase of RAF, to a detriment of MAF was observed, while the percen…
Alcohol abusive use increases facial trauma?
2016
Background Trauma is among the main death causes and morbidity in the world and is often related to the use of alcohol and its abuse has reached massive proportions, no matter if the country is developed or not, being considered as public health problem. Since there are very few randomized and prospective studies in literature about the association of facial trauma and the use of alcohol, this study aims to investigate the impact of alcohol use in facial trauma. Material and Methods This was a prospective and cross sectional study, involving facial trauma patients attended at Oral Maxillofacial Surgery Division of a State Hospital. Variables included patient´s profile, trauma etiology, faci…
An ANRORC approach to the synthesis of perfluoroalkylated 1,2,4-triazole-carboxamides
2009
A series of perfluoroalkyl-1,2,4-triazole-carboxamides has been obtained through an ANRORClike rearrangement (Addition of Nucleophile, Ring-Opening and Ring-Closure) of 5- perfluoroalkyl-1,2,4-oxadiazole-3-carboxamides with methylhydrazine or hydrazine. The initial addition of the bidentate nucleophile to the electrophilic C(5) of the 1,2,4-oxadiazole ring, followed by ring opening and ring closure, leads to the formation of triazoles in good yield under mild experimental conditions. In some cases, a competitive ANRORC-enlargement reaction to form 1,2,4-triazin-6-ones was also observed. Obtained carboxamidotriazoles have also been explored as precursors for the synthesis of 3(5)-perfluoroal…
Paradigm of tunable clustering using Binarization of Consensus Partition Matrices (Bi-CoPaM) for gene discovery
2013
Copyright @ 2013 Abu-Jamous et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Clustering analysis has a growing role in the study of co-expressed genes for gene discovery. Conventional binary and fuzzy clustering do not embrace the biological reality that some genes may be irrelevant for a problem and not be assigned to a cluster, while other genes may participate in several biological functions and should simultaneously belong to multiple clusters. Also, these algorithms cannot generate tight cluster…
Functionnalized magnetite nanoparticles for bimodal imaging MRI/PET
2015
Functionalized magnetite nanoparticles for bimodal MRI/PET imagingSuperParamagnetic Iron Oxide Nanoparticles (SPIONs) have been widely studied in the biomedical field due to their promising application as nanodrugs and MRI (Magnetic Resonance Imaging) contrast agents (T2). In this study, magnetite (Fe3O4) nanoparticles have been developed for use as contrast agents for MRI/PET (Positron emission tomography) double imaging. First, functionalized stable superparamagnetic SPIONs have been synthesized in a continuous hydrothermal reactor. During the synthesis, hydrophilic agents (citric acid, LDOPA, DHCA and PHA) have been grafted on the surface of the nanoparticles. The functionalization of th…