Search results for "cyclic"

showing 10 items of 2439 documents

Oxamidato complexes. Part 4. Electrochemical study of the copper(III)/copper(II) couple in monomeric N,N?-bis(substituent)oxamidatocopper(II) complex…

1993

The electrochemical behaviour of a series of monomeric N,N′-bis(substituent)oxamidato copper(II) complexes of formula Na2[Cu(3,5,3′,5′-X4obbz)]·4H2O [X = Cl (1), Br (2), I (3) and obbz = oxamidobis(benzoato)], Na2-[Cu(obbz)]·4H2O (4), Na2[Cu(5,5′-Me2obbz)]·4H2O (5), Na2[Cu(4,5,4,5′-(MeO)4obbz)]·4H2O(6),Na2[Cu(obp)]· 3.5H2O (7) (obp = oxamidobis(propionato)) and Na2[Cu(pba)]·6H2O (8), [pba = propylenebis(oxamate)] has been investigated by cyclic voltammetry, rotating disk electrode and coulometry in water and dimethylsulphoxide (dmso) solutions. NaNO3 (0.1 M) and n-Bu4NPF6 (0.1 M) were used as supporting electrolytes in H2O and dmso respectively, all solutions being thermostatted at 25 °C. I…

Aqueous solutionLigandOxamideInorganic chemistryMetals and AlloysSubstituentchemistry.chemical_elementMedicinal chemistryCopperInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryRotating disk electrodeCyclic voltammetryOrganometallic chemistryTransition Metal Chemistry
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Electrochemistry of copper complexes with macrocyclic polyamines containing pyrazole units.

2006

The voltammetric behaviour of bi- and mono-nuclear complexes formed in solution by Cu(2+) with three polyazacyclophanes containing pyrazole units in aqueous solution is described. Cyclic and square wave voltammetric responses at glassy carbon electrodes indicate that the reduction of copper-macrocycle complexes in solution takes place in two successive one-electron per Cu transfer processes coupled with preorganization and protonation reactions that mimic the behaviour of superoxide dismutase. The electrochemistry of ternary Cu(2+)-receptor-dopamine complexes exhibits significant differences with respect to the protection of the neurotransmitter from post-electron transfer cyclization react…

Aqueous solutionMacrocyclic CompoundsSuperoxide DismutaseDopamineInorganic chemistryMolecular Mimicrychemistry.chemical_elementProtonationSquare wavePyrazoleGlassy carbonElectrochemistryCopperInorganic Chemistrychemistry.chemical_compoundchemistryPolymer chemistryElectrochemistryOrganometallic CompoundsPolyaminesPyrazolesTernary operationCopperDalton transactions (Cambridge, England : 2003)
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Identification of Bioactive Compounds in Polar and Nonpolar Extracts of Araujia sericifera

2017

Abstract Araujia sericifera is a native perennial, climbing laticiferous shrub from South America that is currently naturalized in many other countries. Previous data describe promising properties for A. sericifera, but no systematic study of its bioactive compounds and possible medicinal applications has been conducted to date. In the present study, aerial parts of A. sericifera (leaves, stems, and fruits) were explored by combining GC-MS and NMR spectroscopy analysis for both nonpolar (hexane) and polar (methanol) extracts. The hexanic extracts contained high amounts of pentacyclic triterpenes including two new metabolites, 3-tigloyl germanicol (18) and 3-tigloyl lupeol (19). The methanol…

Araujia sericiferaQuímica agrícolacancer cell linesTraditional medicinebiologyChemistryConduritol Fbiology.organism_classificationchemistry.chemical_compoundAsclepiadaceaeNMR spectroscopyTrigonellineCarcinoma CellBotanymetabolite profileGC-MSPentacyclic TriterpenesGas chromatography–mass spectrometryAraujia sericiferaPlantes medicinalsHuman colonLupeol
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Continuous images of arcs: Extensions of Cornette's Theorem

2015

In [J.L. Cornette “Image of a Hausdorff arc” is cyclically extensible and reducible Trans. Am. Math. Soc., 199 (1974), pp. 253–267], Cornette proved that a locally connected Hausdorff continuum X is the continuous image of an arc if and only if each of its cyclic elements is the continuous image of an arc. Cyclic elements form a closed null cover of X by retracts of X. We generalize Cornette's result to closed null covers of X with a dendritic structure. We give examples to show that some of our conditions are necessary and we pose some open questions.

Arc (geometry)Discrete mathematicsPure mathematicsCover (topology)Continuum (topology)Images of arcs; Locally connected; Cyclic element; Null familyNull (mathematics)Hausdorff spaceGeometry and TopologyMathematicsImage (mathematics)Topology and Its Applications
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Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial B…

2014

International audience; The objective of this study was to evaluate the biological activities of the major phytosterols present in argan oil (AO) and in cactus seed oil (CSO) in BV2 microglial cells. Accordingly, we first determined the sterol composition of AO and CSO, showing the presence of Schottenol and Spinasterol as major sterols in AO. While in CSO, in addition to these two sterols, we found mainly another sterol, the Sitosterol. The chemical synthesis of Schottenol and Spinasterol was performed. Our results showed that these two phytosterols, as well as sterol extracts from AO or CSO, are not toxic to microglial BV2 cells. However, treatments by these phytosterols impact the mitoch…

Argan oilABCA1Biochemistrychemistry.chemical_compoundMice0302 clinical medicineSchottenolBV2 cellspolycyclic compoundsCactus oilATP Binding Cassette Transporter Subfamily G Member 1Liver X ReceptorsMembrane Potential Mitochondrial0303 health sciencesbiologyOpuntiafood and beveragesPhytosterolsOrphan Nuclear ReceptorsSterolsBiochemistryABCG1030220 oncology & carcinogenesisSeeds[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]lipids (amino acids peptides and proteins)LXRMicrogliaATP Binding Cassette Transporter 1food.ingredientABCG1LipoproteinsBiophysicsStigmasterol[ PHYS.COND.CM-MS ] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]Ficus indicaCell Line03 medical and health sciencesfoodAnimalsPlant OilsLiver X receptorMolecular BiologySpinasterol030304 developmental biologyCholesterolCell BiologySitosterolsSterolSpinasterolchemistryNuclear receptorGene Expression RegulationArgan oilABCA1biology.proteinATP-Binding Cassette Transporters
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Electrophysiological and Behavioral Responses of Oriental Fruit Moth to the Monoterpenoid Citral Alone and in Combination With Sex Pheromone

2013

The monoterpenoid citral synergized the electroantennogram (EAG) response of male Grapholita molesta (Busck) antennae to its main pheromone compound Z8-12:OAc. The response to a 10-μg pheromone stimulus increased by 32, 45, 54, 71 and 94% with the addition of 0.1, 1, 10, 100 and 1,000 μg of citral, respectively. There was no detectable response to 0.1, 1, or 10 μg of citral; the response to 100 and 1,000 μg of citral was 31 and 79% of the response to 10 μg of Z8-12:OAc. In a flight tunnel, citral affected the mate-seeking behavior of males. There was a 66% reduction in the number of males orientating by flight to a virgin calling female when citral was emitted at 1,000 ng/min ≍1 cm downwind…

Arthropod AntennaeMaleAcyclic MonoterpenesMothsCitralInsect ControlSexual Behavior Animalchemistry.chemical_compoundGrapholita molesta citral sex pheromone sensory adaptation sexual behaviorBotanyAnimalsFood scienceSex AttractantsEcology Evolution Behavior and SystematicsDose-Response Relationship DrugEcologybiologybiology.organism_classificationGrapholita molestaSettore AGR/11 - Entomologia Generale E ApplicatachemistrySexual behaviorInsect ScienceSex pheromoneMonoterpenesPheromoneFemale
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The influence of electron delocalization upon the stability and structure of potential N-heterocyclic carbene precursors with 1,3-diaryl-imidazolidin…

2010

Targeting N-heterocyclic carbenes (NHCs) with increased π-acceptor character featuring N-fluorophenyl substituents, the molecular 2-chloro-1,3-bis(fluorophenyl)imidazolidine-4,5-diones (1a–c) were isolated from the condensation of the corresponding formamidine with oxalyl chloride. These formal adducts of NHCs with hydrogen chloride demonstrated reactivity akin to that of alkyl halides: 1,3,1′,3′-tetrakis(2,6-dimethylphenyl)-[2,2′]diimidazolidinyl-4,5,4′,5′-tetraone (2b) was formed via the reductive coupling of 1b, while 1,3-bis(2,6-diisopropylphenyl)-4,5-dioxoimidazolidin-2-yl acetate (3c) was formed as the result of a metathesis reaction with mercury(II) acetate. Chloride abstraction resu…

ArylN-heterosykliset karbeenitGeneral ChemistryMedicinal chemistryChlorideCatalysischemistry.chemical_compoundOxalyl chloridechemistryImidazolidineHexafluorophosphateElectrophileMaterials ChemistrySalt metathesis reactionmedicineOrganic chemistryN-heterocyclic carbenesCarbenemedicine.drugNew Journal of Chemistry
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Emerging brominated flame retardants and dechlorane-related compounds in European eels (Anguilla anguilla) from Latvian lakes

2017

Abstract Fifteen halogenated flame retardants (HFRs) including seven emerging brominated flame retardants (EBFRs) and eight dechlorane-related compounds (DRCs) were analyzed in eels (Anguilla anguilla) sampled from five Latvian lakes. Out of the seven EBFRs, hexabromocyclododecane (HBCD) and decabromodiphenyl ethane (DBDPE) were found in eels in quantifiable concentrations, up to 6.58 and 33.0 ng g−1 lipid weight (l.w.), respectively. The mean total concentration of DRCs (∑DRC) in the samples was 0.62 ng g−1 l.w. and the geographical distribution of DRC contamination was nearly uniform among the selected lakes. Dechlorane 602 (Dec 602) was the predominant component, whereas the composition …

AsiaEnvironmental EngineeringHalogenation010504 meteorology & atmospheric sciencesHealth Toxicology and Mutagenesis010501 environmental sciencesAquatic biota01 natural scienceschemistry.chemical_compoundHalogenated Diphenyl EthersHydrocarbons ChlorinatedAnimalsEnvironmental ChemistryPolycyclic CompoundsFlame Retardants0105 earth and related environmental sciencesHexabromocyclododecanePublic Health Environmental and Occupational HealthGeneral MedicineGeneral ChemistryContaminationAnguillaLatviaPollutionHydrocarbons BrominatedEuropeLakesDecabromodiphenyl ethanechemistryAquatic environmentEnvironmental chemistryComposition (visual arts)Water Pollutants ChemicalBromobenzenesEnvironmental MonitoringChemosphere
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Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothal…

2015

Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the present study. Cell proliferation (phospho-H3(+) or BrdU(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (GFAP(+)), and microglia (Iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with URB597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). Repeated URB597 treatment increased the plasma levels of the N-acylethanolamine…

AstrocitosNeurobiologia del desenvolupamentAmidohidrolasasCannabinoid receptorCarbamatos:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Caspases [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Neurogenesis [Medical Subject Headings]medicine.medical_treatment:Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose [Medical Subject Headings]Apoptosis:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight [Medical Subject Headings]chemistry.chemical_compound:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB1 [Medical Subject Headings]0302 clinical medicine:Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids Acyclic::Carbamates [Medical Subject Headings]Fatty acid amide hydrolaseReceptor cannabinoide CB1:Organisms::Eukaryota::Animals [Medical Subject Headings]FAAHGliosishealth care economics and organizations:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine [Medical Subject Headings]:Chemicals and Drugs::Lipids::Glycerides::Triglycerides [Medical Subject Headings]Original Research0303 health sciencesNeurogenesisBenzamidas:Chemicals and Drugs::Polycyclic Compounds::Steroids::Cholestanes::Cholestenes::Cholesterol [Medical Subject Headings]Endocannabinoid systemEtanolaminas3. Good healthEndocannabinoides:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Unsaturated::Fatty Acids Monounsaturated::Oleic Acids [Medical Subject Headings]CannabinoidesMicroglíalipids (amino acids peptides and proteins)medicine.symptomColesterol:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Terpenes::Cannabinoids [Medical Subject Headings]:Chemicals and Drugs::Lipids::Fatty Acids::Palmitic Acids [Medical Subject Headings]psychological phenomena and processesProliferación celularmedicine.medical_specialtyCerebroNeurogenesiseducationBiologyBromodesoxiuridina:Anatomy::Nervous System::Neuroglia::Microglia [Medical Subject Headings]Triglicéridoslcsh:RC321-571Ácidos oléicosRatas03 medical and health sciencesCellular and Molecular NeuroscienceInternal medicineHipocampomedicineCaspasa 3:Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hippocampus [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings]lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyPalmitoylethanolamide:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases [Medical Subject Headings]Cannabinoids:Anatomy::Cells::Neuroglia::Astrocytes [Medical Subject Headings]Peso corporalEnergy metabolism:Anatomy::Nervous System::Central Nervous System::Brain [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus [Medical Subject Headings]URB597:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Gliosis [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Amines::Amino Alcohols::Ethanolamines [Medical Subject Headings]Muerte celular:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings]EndocrinologyURB597chemistryGliosisnervous systemGlucosaCannabinoidEnergy Metabolism:Chemicals and Drugs::Organic Chemicals::Amides::Benzamides [Medical Subject Headings]HipotálamoÁcidos palmíticos030217 neurology & neurosurgeryNeuroscienceFrontiers in Cellular Neuroscience
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Urban organic aerosol composition in eastern China differs from north to south:Molecular insight from a liquid chromatography-mass spectrometry (Orbi…

2021

Air pollution by particulate matter in China affects human health, the ecosystem and the climate. However, the chemical composition of particulate aerosol, especially of the organic fraction, is still not well understood. In this study, particulate aerosol samples with a diameter of ≤2.5 µm (PM2.5) were collected in January 2014 in three cities located in northeast, east and southeast China, namely Changchun, Shanghai and Guangzhou. Organic aerosol (OA) in the PM2.5 samples was analyzed by an ultrahigh-performance liquid chromatograph (UHPLC) coupled to a high-resolution Orbitrap mass spectrometer in both negative mode (ESI-) and positive mode electrospray ionization (ESI+). After non-targe…

Atmospheric ScienceELECTROSPRAY-IONIZATION010504 meteorology & atmospheric sciencesQC1-999Electrospray ionizationCHONAir pollution010501 environmental sciencesmedicine.disease_causeMass spectrometryOXIDATION01 natural sciencesPOLYCYCLIC AROMATIC-HYDROCARBONSPOLLUTIONCHEMISTRYmedicineFIELDQD1-999Chemical compositionEMISSIONS0105 earth and related environmental sciencesSEVERE HAZEChemistryPhysicsORGANOSULFATESParticulatesAerosolChemistryEnvironmental chemistryMass spectrum
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