Search results for "d AU"
showing 10 items of 747 documents
Nuevos datos sobre Ferula loscosii (Lange) Willk. (Apiaceae) en la provincia de Alicante
2012
Se amplía el área de distribución del endemismo ibérico Ferula loscosii en el noroeste de la provincia de Alicante, al haber sido hallados nuevos núcleos poblacionales situados a una distancia de hasta 4 km respecto al único núcleo anteriormente conocido en Villena. Asimismo se adjunta abundante material gráfico y descriptivo sobre las plantas alicantinas para facilitar tanto su comparación con el resto de poblaciones ibéricas como la futura detección de nuevas poblaciones de esta especie. The distribution area of the Iberian endemism Ferula loscosii is enlarged in NW Alicante province. New populations have been found which are located up to 4 km far from the single population currently kno…
Rapid automatized naming in early literacy
2019
Esta comunicación se encuentra disponible en la siguiente URL: http://www.infad.eu/RevistaINFAD/OJS/index.php/IJODAEP/article/view/1465/1274 Este número está dedicado a la "Psicología de la Educación y Saberes Originarios". Although the relation between Rapid Automatized Naming (RAN) and Reading is clear, there is no a standardized test to measure the speed of naming in early literacy. The aim is to explore and confirm the factorial structure of the RAN test developed by Wolf and Denkla (2003) in children. RAN test was administred to 442 children aged 4-5 years. Results highlighted two factors: a “nonalphanumeric components” factor which includes “RAN colors” and “RAN images” and an “alphan…
Statin-induced autoimmune myositis: a proposal of an “experience-based” diagnostic algorithm from the analysis of 69 patients
2023
AbstractStatin-induced autoimmune myositis (SIAM) represents a rare clinical entity that can be triggered by prolonged statin treatment. Its pathogenetic substrate consists of an autoimmune-mediated mechanism, evidenced by the detection of antibodies directed against the 3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR Ab), the target enzyme of statin therapies. To facilitate the diagnosis of nuanced SIAM clinical cases, the present study proposes an “experience-based” diagnostic algorithm for SIAM. We have analyzed the clinical data of 69 patients diagnosed with SIAM. Sixty-seven patients have been collected from the 55 available and complete case records regarding SIAM in the l…
Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis.
2014
It has been suggested that cancer stem cells (CSC) may play a central role in oncogenesis, especially in undifferentiated tumours. Anaplastic thyroid carcinoma (ATC) has characteristics suggestive of a tumour enriched in CSC. Previous studies suggested that the stem cell factorSOX2has a preeminent hierarchical role in determining the characteristics of stem cells in SW1736 ATC cell line. In detail, silencing SOX2 in SW1736 is able to suppress the expression of the stem markers analysed, strongly sensitizing the line to treatment with chemotherapeutic agents. Therefore, in order to further investigate the role of SOX2 in ATC, a competing endogenous RNA (ceRNA) analysis was conducted in order…
Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3.
2014
Many neurodegenerative disorders present with sensory loss. In the group of hereditary sensory and autonomic neuropathies loss of nociception is one of the disease hallmarks. To determine underlying factors of sensory neurodegeneration we performed whole-exome sequencing in affected individuals with the disorder. In a family with sensory neuropathy with loss of pain perception and destruction of the pedal skeleton we report a missense mutation in a highly conserved amino acid residue of atlastin GTPase 3 (ATL3), an endoplasmic reticulum-shaping GTPase. The same mutation (p.Tyr192Cys) was identified in a second family with similar clinical outcome by screening a large cohort of 115 patients …
Simulation-Based Analysis of "What-If" Scenarios with Connected and Automated Vehicles Navigating Roundabouts.
2022
Despite the potential of connected and automated vehicles (CAVs), there are still many open questions on how road capacity can be influenced and what methods can be used to assess its expected benefits in the progressive transition towards fully cooperative driving. This paper contributes to a better understanding of the benefits of CAV technologies by investigating mobility-related issues of automated vehicles operating with a cooperative adaptive cruise control system on roundabout efficiency using microscopic traffic simulation. The availability of the adjustment factors for CAVs provided by the 2022 Highway Capacity Manual allowed to adjust the entry capacity equations to reflect the pr…
A NEW COMPLEXITY FUNCTION FOR WORDS BASED ON PERIODICITY
2013
Motivated by the extension of the critical factorization theorem to infinite words, we study the (local) periodicity function, i.e. the function that, for any position in a word, gives the size of the shortest square centered in that position. We prove that this function characterizes any binary word up to exchange of letters. We then introduce a new complexity function for words (the periodicity complexity) that, for any position in the word, gives the average value of the periodicity function up to that position. The new complexity function is independent from the other commonly used complexity measures as, for instance, the factor complexity. Indeed, whereas any infinite word with bound…
In light of the ends. Copyright hysteresis and private copy exception after the British Academy of Songwriters, Composers and Authors (BASCA) and oth…
2015
In British Academy of Songwriters, Composers and Authors (BASCA) and others v Secretary of State for Business, Innovation and Skills, the High Court of Justice in matter of private copy exception provides the twofold prime opportunity to shed light on the state of the art of copyright in the UK and to flesh out the idea of 'legal hysteresis’. I support the reintroduction of the private copy exception, possibly in a less narrow fashion, and I explain the reasons why I am confident that my expectations will be fulfilled.
LES TABLEAUX DE BORD DU CAPITAL INTELLECTUEL
2009
Cet article a pour objectif de présenter et d'analyser les tableaux de bord du capital intellectuel qui constituent un modèle alternatif au Balanced Scorecard. Dans une première partie, nous retraçons les origines et les fondements des tableaux de bord du capital intellectuel. Puis dans une seconde partie, nous décrivons les différentes façons d'appréhender le capital intellectuel pour dans une troisième partie analyser des exemples de tableaux de bord du capital intellectuel.
Research of Complex Forms in Cellular Automata by Evolutionary Algorithms
2004
This paper presents an evolutionary approach for the search for new complex cellular automata. Two evolutionary algorithms are used: the first one discovers rules supporting gliders and periodic patterns, and the second one discovers glider guns in cellular automata. An automaton allowing us to simulate AND and NOT gates is discovered. The results are a step toward the general simulation of Boolean circuits by this automaton and show that the evolutionary approach is a promising technic for searching for cellular automata that support universal computation.