Search results for "dLN"

showing 10 items of 51 documents

Updated insights into the mechanism of action and clinical profile of the immunoadjuvant QS-21: A review

2019

Background Vaccine adjuvants are compounds that significantly enhance/prolong the immune response to a co-administered antigen. The limitations of the use of aluminium salts that are unable to elicite cell responses against intracellular pathogens such as those causing malaria, tuberculosis, or AIDS, have driven the development of new alternative adjuvants such as QS-21, a triterpene saponin purified from Quillaja saponaria. Purpose The aim of this review is to attempt to clarify the mechanism of action of QS-21 through either receptors or signaling pathways in vitro and in vivo with special emphasis on the co-administration with other immunostimulants in new adjuvant formulations, called a…

InflammasomesT-Lymphocytesmedicine.medical_treatmentHerpes zosterPharmaceutical ScienceMonophosphoryl Lipid AAPCs antigen presenting cellsMiceCMI cell mediated immunity0302 clinical medicineDrug DiscoveryHerpes Zoster VaccineMedicineNSCLC non small cell lung carcinomaCancerImmunity CellularVaccines Synthetic0303 health sciencesImmunogenicityIl-2 interleukine 2HIV human immunodeficiency virusLipid A030220 oncology & carcinogenesisCytokinesMolecular MedicineDCs dendritic cellsNK natural killerAdjuvantTLR Toll-like receptorHerpes Zoster VaccineCD cluster of differentiationAntigen-Presenting CellsCTL cytotoxic T lymphocytesHZ herpes zosterMPL 3-deacylated monophosphoryl lipidVaccine adjuvantImmunoadjuvantArticleVZV varicella zoster virus03 medical and health sciencesImmune systemAdjuvants ImmunologicAntigenPAMPs pathogen-associated molecular patternsMalaria VaccinesPRRs pathogen recognition receptorsQS-21 Quillaja saponaria Molina-fraction 21AnimalsMHC major histocompatibility complexMtb Mycobacterium tuberculosis bacteriaSARS severe acute respiratory syndromeAntigen-presenting cellIFN-γ interferon-gamma030304 developmental biologyPharmacologybusiness.industryA-β amyloid-betaTNF-α tumor necrosis factor-alphaSaponinsQS-21MalariaQuillaja saponariaComplementary and alternative medicineTCR T-cell receptorLiposomesImmunologyKLH keyhole limpet hemocyaninbusinessdLN draining lymph nodesMAPK mitogen activated protein kinasePhytomedicine
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The role of humidity in associations of high temperature with mortality: A multicountry, multicity study

2019

BACKGROUND: There is strong experimental evidence that physiologic stress from high temperatures is greater if humidity is higher. However, heat indices developed to allow for this have not consistently predicted mortality better than dry-bulb temperature. OBJECTIVES: We aimed to clarify the potential contribution of humidity an addition to temperature in predicting daily mortality in summer by using a large multicountry dataset. METHODS: In 445 cities in 24 countries, we fit a time-series regression model for summer mortality with a distributed lag nonlinear model (DLNM) for temperature (up to lag 3) and supplemented this with a range of terms for relative humidity (RH) and its interaction…

Health Toxicology and MutagenesisHot temperature010501 environmental sciencesAtmospheric sciences01 natural sciencesrelative humidity (RH)Hot Temperature03 medical and health sciencesArbetsmedicin och miljömedicin0302 clinical medicineHeat-related mortality030212 general & internal medicineMortality trends0105 earth and related environmental sciencesHeat related mortalitydistributed lag nonlinear model (DLNM)TemperaturesExtramuralResearchPublic Health Environmental and Occupational Healthhumidityfood and beveragesHumidityOccupational Health and Environmental Healthmortalityhumanities3. Good health13. Climate actionEnvironmental science
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"Table 165" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y34) distribution at c.m. energy 91.20 GeV.

Single Differential Cross SectionDSIG/DLNY34Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::Experiment91.2Nuclear Experiment
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"Table 159" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y23) distribution at c.m. energy 161.00 GeV.

Single Differential Cross SectionDSIG/DLNY23Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::ExperimentNuclear Experiment161.0
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"Table 174" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y45) distribution at c.m. energy 133.00 GeV.

Single Differential Cross Section133.0DSIG/DLNY45Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 150" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y12) distribution at c.m. energy 133.00 GeV.

Single Differential Cross Section133.0DSIG/DLNY12Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 178" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y45) distribution at c.m. energy 189.00 GeV.

Single Differential Cross Section189.0DSIG/DLNY45Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 2" of "Production of K0 and Lambda in hadronic Z decays"

1994

No description provided.

E+ E- --> LAMBDA XInclusiveStrange productionE+ E- --> Z0E+ E- ScatteringExclusive91.2D2SIG/DLN1/XDouble Differential Cross SectionE+ E- --> LAMBDABAR X
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"Table 180" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y56) distribution at c.m. energy 91.20 GeV.

Single Differential Cross SectionDSIG/DLNY56Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::Experiment91.2Nuclear Experiment
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"Table 181" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

LN(Y56) distribution at c.m. energy 133.00 GeV.

Single Differential Cross Section133.0DSIG/DLNY56Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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