Search results for "database."
showing 10 items of 2119 documents
Unified computing facility design based on open source software
2012
The article describes e-infrastructure development in Latvia and migration to national Cloud as regional partner facility (RPF) in European Union (EU). In Latvia many public and private Computing Clouds is in operation and problem is how to integrate these resources as one RPF and how to design one unified computing facility that is used for many different applications. The authors offer their solution at Cloud software as a Service and Hardware as a Service level which is based on usage of open source packaged bundles.
Retrieving Open Source Software Licenses
2006
Open Source Software maintenance and reuse require identifying and comprehending the applied software licenses. This paper first characterizes software maintenance, and open source software (OSS) reuse which are particularly relevant in this context. The information needs of maintainers and reusers can be supported by reverse engineering tools at different information retrieval levels. The paper presents an automated license retrieval approach called ASLA. User needs, system architecture, tool features, and tool evaluation are presented. The implemented tool features support identifying source file dependencies and licenses in source files, and adding new license templates for identifying l…
Mild OSA and arterial hypertension in the European Sleep Apnoea Database cohort study
2019
Background: Mild obstructive sleep apnoea (OSA) is highly prevalent; however its association with important clinical outcomes like arterial hypertension remains unknown. Aims: To investigate the association between mild OSA and hypertension in the European Sleep Apnoea Database (ESADA) cohort after adjusting for relevant confounding factors. Methods: A multicentric sample of 7995 adults from the ESADA cohort with simple snoring or mild OSA at PG or PSG was studied. We compared the predictive value of mild OSA (AHI 5- Results: Arterial hypertension prevalence was 37% in mild OSA (n=1566) compared to 22% in non-apnoeic snorers (n=793, p Conclusion: Our results suppport the hypothesis that mi…
Smoking ban in public places and myocardial infarction hospitalizations in high cardiovascular risk European country – insights from the Polish natio…
2019
Introduction Previous studies demonstrated a possible positive effect of a smoking ban in public places on cardiovascular outcomes. However, little is known about the influence of such regulations in Poland, a country with a high cardiovascular risk. Objectives We aimed to evaluate the association of hospitalization rates for acute myocardial infarction (AMI) in Poland before and after the introduction of the smoking ban in public places in November 2010. Patients and methods The Nationwide Acute Myocardial Infarction Database (AMI‑PL) was searched for the cases of AMI that occurred between 2009 and 2014. The analysis considered sex, age (20-64 years vs 65 years or older), and the place of …
Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: Longitudinal data from the European S…
2017
Introduction: The effect of continuous positive airway pressure (CPAP) treatment on body weight and central obesity in obstructive sleep apnea (OSA) patients is still unclear. Objectives: We aimed to study body composition change during CPAP treatment in the European Sleep Apnea Database (ESADA). Methods: OSA patients with a CPAP treatment follow-up time of more than 30 days in the ESADA registry were selected (n=2015). Body mass index (BMI), body weight, waist-, hip- and neck-circumferences were assessed at baseline and follow-up (median [interquartile range], 242 [380] days). Predictors for body composition changes with CPAP were analyzed adjusting for confounders. Results: Overall, there…
Assessing the format and content of journal published and non-journal published rapid review reports: A comparative study
2020
Background As production of rapid reviews (RRs) increases in healthcare, knowing how to efficiently convey RR evidence to various end-users is important given they are often intended to directly inform decision-making. Little is known about how often RRs are produced in the published or unpublished domains, and what and how information is structured. Objectives To compare and contrast report format and content features of journal-published (JP) and non-journal published (NJP) RRs. Methods JP RRs were identified from key databases, and NJP RRs were identified from a grey literature search of 148 RR producing organizations and were sampled proportionate to cluster size by organization and pro…
Validation of the SOS/umu test using test results of 486 chemicals and comparison with the Ames test and carcinogenicity data
1996
The present study gives a comprehensive update of all umu genotoxicity assay results published so far. The available data of 486 chemicals investigated with the umu test are compared with the Ames test (274 compounds) as well as rodent carcinogenicity data (179 compounds). On the whole, there is good agreement between the umu test and the Ames test results, with a concordance of about 90%. The umu test was able to detect 86% of the Ames mutagens, while the Ames test (using at least 5 strains) detected 97% of the umu positive compounds. The elimination of TA102 from the set of Ames tester strains reduced the percentage of detectable umu genotoxins from 97 to 86%. The agreement between carcin…
PyCellBase, an efficient python package for easy retrieval of biological data from heterogeneous sources.
2019
Background Biological databases and repositories are incrementing in diversity and complexity over the years. This rapid expansion of current and new sources of biological knowledge raises serious problems of data accessibility and integration. To handle the growing necessity of unification, CellBase was created as an integrative solution. CellBase provides a centralized NoSQL database containing biological information from different and heterogeneous sources. Access to this information is done through a RESTful web service API, which provides an efficient interface to the data. Results In this work we present PyCellBase, a Python package that provides programmatic access to the rich RESTfu…
Analysis of Lipid Experiments (ALEX): A Software Framework for Analysis of High-Resolution Shotgun Lipidomics Data
2013
Global lipidomics analysis across large sample sizes produces high-content datasets that require dedicated software tools supporting lipid identification and quantification, efficient data management and lipidome visualization. Here we present a novel software-based platform for streamlined data processing, management and visualization of shotgun lipidomics data acquired using high-resolution Orbitrap mass spectrometry. The platform features the ALEX framework designed for automated identification and export of lipid species intensity directly from proprietary mass spectral data files, and an auxiliary workflow using database exploration tools for integration of sample information, computat…
Local dimensionality reduction and supervised learning within natural clusters for biomedical data analysis
2006
Inductive learning systems were successfully applied in a number of medical domains. Nevertheless, the effective use of these systems often requires data preprocessing before applying a learning algorithm. This is especially important for multidimensional heterogeneous data presented by a large number of features of different types. Dimensionality reduction (DR) is one commonly applied approach. The goal of this paper is to study the impact of natural clustering--clustering according to expert domain knowledge--on DR for supervised learning (SL) in the area of antibiotic resistance. We compare several data-mining strategies that apply DR by means of feature extraction or feature selection w…