Search results for "ddc:6"

showing 10 items of 788 documents

The contribution of acetylcholine and dopamine to subprocesses of visual working memory--what patients with amnestic mild cognitive impairment and Pa…

2014

Attentional selection, i.e. filtering out of irrelevant sensory input and information storage are two crucial components of working memory (WM). It has been proposed that the two processes are mediated by different neurotransmitters, namely acetylcholine for attentional selection and dopamine for memory storage. However, this hypothesis has been challenged by others, who for example linked a lack in dopamine levels in the brain to filtering deficits. Here we tested the above mentioned hypothesis in two patient cohorts which either served as a proxy for a cholinergic or a dopaminergic deficit. The first group comprised 18 patients with amnestic mild cognitive impairment (aMCI), the second 22…

Malephysiopathology [Cognitive Dysfunction]Parkinson's diseaseCognitive NeuroscienceDopamineModels NeurologicalExperimental and Cognitive Psychologyphysiopathology [Brain]Neuropsychological TestsCohort StudiesBehavioral Neurosciencechemistry.chemical_compoundDopaminemedicineHumansAttentionCognitive Dysfunctionddc:610metabolism [Dopamine]NeurotransmitterAgedWorking memoryDopaminergicBrainCognitionParkinson Diseasephysiopathology [Amnesia]Middle Agedphysiology [Visual Perception]medicine.diseaseAcetylcholineMemory Short-Termchemistryphysiology [Memory Short-Term]physiology [Attention]Visual PerceptionCholinergicFemalephysiopathology [Parkinson Disease]AmnesiaPsychologyNeurosciencemetabolism [Acetylcholine]Acetylcholinemedicine.drugNeuropsychologia
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DSM-IV Combined Type ADHD Shows Familial Association With Sibling Trait Scores

2008

Contains fulltext : 69060.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments. Molecular genetic studies have been successful in identifying genetic variants associated with ADHD, particularly with DSM-IV inattentive and combined subtypes. Quantitative trait locus (QTL) approaches to linkage and association mapping have yet to be widely used in ADHD research, although twin studies investigating individual differences suggest that genetic liability for ADHD is continuously distributed throughout the population, u…

Malequantitative geneticsGenetics and epigenetic pathways of disease [NCMLS 6]Genetic Linkageattention deficit hyperactivity disorder (ADHD)GENOMEWIDE SCANMedizin2804 Cellular and Molecular NeuroscienceNeuroinformatics [DCN 3]MULTIPLE-REGRESSION ANALYSIS2738 Psychiatry and Mental Health0302 clinical medicineDIFFICULTIES QUESTIONNAIREDEFICIT-HYPERACTIVITY DISORDERTwins DizygoticPerception and Action [DCN 1]Genetics(clinical)DF analysisAssociation mappingGenetics (clinical)linkage studyGeneticseducation.field_of_studyATTENTION-DEFICIT/HYPERACTIVITY DISORDERDOPAMINE TRANSPORTER GENE10058 Department of Child and Adolescent PsychiatryDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthCHILD-BEHAVIOR CHECKLISTConduct disorderRegression AnalysisFemalemedicine.symptomFunctional Neurogenomics [DCN 2]Clinical psychology2716 Genetics (clinical)Quantitative Trait LociPopulation610 Medicine & healthQuantitative trait locusBiologyImpulsivityMental health [NCEBP 9]behavioral disciplines and activitiesINDIVIDUAL-DIFFERENCESInterviews as TopicGenomic disorders and inherited multi-system disorders [IGMD 3]quantitative trait locus (QTL)03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]mental disordersmedicineHumansSibling RelationsAttention deficit hyperactivity disorderFamilyGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersSiblingeducationTWIN DATAmedicine.diseaseTwin study030227 psychiatryGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityCONDUCT DISORDER030217 neurology & neurosurgeryAmerican Journal of Medical Genetics. Part B: Neuropsychiatric Genetics
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Contrasting parental roles shape sex differences in poison frog space use but not navigational performance

2022

Sex differences in vertebrate spatial abilities are typically interpreted under the adaptive specialization hypothesis, which posits that male reproductive success is linked to larger home ranges and better navigational skills. The androgen spillover hypothesis counters that enhanced male spatial performance may be a byproduct of higher androgen levels. Animal groups that include species where females are expected to outperform males based on life-history traits are key for disentangling these hypotheses. We investigated the association between sex differences in reproductive strategies, spatial behavior, and androgen levels in three species of poison frogs. We tracked individuals in natura…

Malesammakotsukupuolierotpaikkatietoanalyysi000 Computer science knowledge & systemseläinten käyttäytyminenGeneral Biochemistry Genetics and Molecular BiologyAnimals; Male; Female; Sex Characteristics; Poisons; Androgens; Anura; Spatial NavigationSex Factorsddc:630Animals000 Informatik Wissen SystemeGeneral Immunology and MicrobiologylisääntymiskäyttäytyminenBehavior AnimalGeneral NeuroscienceGeneral Medicineddc:elinpiirit (biologia)adaptive specialization hypothesis ; Allobates femoralis ; amphibians ; Dendrobates tinctorius ; ecology ; evolutionary biology ; Oophaga sylvatica ; testosterone spilloverAndrogens570 Life sciences; biology590 Animals (Zoology)FemaleAnura570 Biowissenschaften; Biologie
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Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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Safety of endovascular treatment in acute stroke patients taking oral anticoagulants

2017

International journal of stroke 12(4), 412-415 (2017). doi:10.1177/1747493016677986

Maletherapeutic use [Anticoagulants]medicine.medical_specialtyMedizinAdministration Oral030204 cardiovascular system & hematologyBrain IschemiaBrain ischemia03 medical and health sciences0302 clinical medicineetiology [Intracranial Hemorrhages]Modified Rankin ScaleInterquartile rangeAntithromboticmedicineHumansThrombolytic Therapyddc:610Prospective StudiesRegistriesadverse effects [Anticoagulants]Prospective cohort studyStrokeAgedAged 80 and overbusiness.industryConfoundingAnticoagulantsmethods [Thrombolytic Therapy]complications [Brain Ischemia]Middle Agedmedicine.diseasedrug therapy [Stroke]Surgerysurgery [Stroke]StrokeTreatment Outcomeadministration & dosage [Anticoagulants]Neurologydrug therapy [Brain Ischemia]FemaleObservational studydrug therapy [Intracranial Hemorrhages]businessIntracranial Hemorrhages030217 neurology & neurosurgery
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Construct validity of the anxiety sensitivity index-3 in clinical samples

2012

"Using two clinical samples of patients, the presented studies examined the construct validity of the recently revised Anxiety Sensitivity Index-3 (ASI-3). Confirmatory factor analyses established a clear three-factor structure that corresponds to the postulated subdivision of the construct into correlated somatic, social, and cognitive components. Participants with different primary clinical diagnoses differed from each other on the ASI-3 subscales in theoretically meaningful ways. Specifically, the ASI-3 successfully discriminated patients with anxiety disorders from patients with nonanxiety disorders. Moreover, patients with panic disorder or agoraphobia manifested more somatic concerns …

Malevaliditymental disorderPsychometricspsychische StörungStatistics as TopicdiagnosticFear of negative evaluationCognitionddc:150PsychologySomatoform DisordersApplied Psychologyklinische PsychologieconstructSozialwissenschaften SoziologiePsychological Disorders Mental Health Treatment and PreventionKonstruktanxietyAnxiety DisordersValiditätFaktorenanalyseClinical Psychologypsychische Störungen Behandlung und PräventionAnxietyddc:30010700Femaleclinical psychologymedicine.symptomPsychologyPsychological Testing Psychological Counseling Psychological MethodologyClinical psychologyAdultDepartment Psychologiemedicine.medical_specialtyPsychometricsscale constructionAngstfactor analysisTypologieSensitivity and SpecificityDiagnostikmental disordersSkalenkonstruktionmedicineHumansddc:610psychologische Diagnostik und Beratung psychologische MethodenPsychiatrySocial sciences sociology anthropologyErhebungstechniken und Analysetechniken der SozialwissenschaftenAnalysis of VariancePanic disorderDiscriminant validityReproducibility of ResultsConstruct validitymedicine.diseaseMethods and Techniques of Data Collection and Data Analysis Statistical Methods Computer MethodsPsychologieAnxiety sensitivityInstitut für ErnährungswissenschaftASI-3; Angstsensitivitätsindex; Anxiety Sensitivity IndextypologyCognition DisordersFactor Analysis Statistical10200Agoraphobia
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Luminescence dating of loess deposits from the Remagen-Schwalbenberg site, Western Germany

2015

Geochronometria 42(1), 67-77 (2015). doi:10.1515/geochr-2015-0008

Marine isotope stageThermoluminescence datingGeochemistryFeldsparPaleosol620visual_artLoessEarth and Planetary Sciences (miscellaneous)visual_art.visual_art_mediumStadialddc:620TephraGeomorphologyQuartzGeology
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Market valuation and acquiring firm performance in the short and long term: Out-of-sample evidence from Spain

2019

We investigate bidder’s short- and long-term performance in periods of high and low valuation market in response to announcements of acquisitions carried out by Spanish listed firms over the period 1991–2016. We find that acquirers of unlisted targets fully react at the announcement date in high valuation periods, meanwhile the underreaction of listed target bidders at the moment of the announcement in low valuation markets is the result of return continuations. In addition, we find that the market reaction do not depend on recent merger history. Therefore, we provide evidence that bidder reaction to acquisitions is not consistent with the predictions of market sentiment (optimism) after c…

Market sentimentEconomics and EconometricsFirm acquisitionStrategy and ManagementHigh valuationMonetary economicsUnderreactionddc:6500502 economics and businessG34050207 economicsBusiness and International ManagementMarket sentimentMarket valueValuation (finance)050208 financeG1405 social sciencesL33Market reactionGeneral MedicineGeneral Business Management and AccountingD81Out of sample050211 marketingManagerial overconfidenceBusinessMarket valuation050203 business & managementBRQ Business Research Quarterly
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Networking and knowledge creation: Social capital and collaborative innovation in responding to the COVID-19 crisis

2022

This study empirically explores the role of social capital in creating collaborative innovation and collective intelligence and maintaining organizational sustainability in the unprecedented COVID-19 crisis. Data were collected from a sample of 289 managers, directors and heads of departments of top 50 manufacturing firms in Jordan and analyzed using Smart-PLS-SEM. The results indicate that social capital significantly impacts collaborative innovation, collective intelligence and organization sustainability during the COVID-19 crisis. They also reveal that collective intelligence significantly impacts collaborative innovation and organization sustainability. This study enriches the literatu…

MarketingEconomics and Econometricsorganizational sustainabilityCollective intelligenceCollaborative innovationCOVID-19Organizational sustainabilitycollective intelligenceUNESCO::CIENCIAS ECONÓMICASSocial capitalManagement of Technology and Innovationddc:650social capitalcollaborative innovationBusiness and International ManagementSocial capital ; Collaborative innovation ; Collective intelligence ; Organizational sustainability ; COVID-19Journal of Innovation & Knowledge
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¿Quién paga, quién gana? El caso de la venta del BdV

2016

ResumenEl proceso de venta del Banco de Valencia gestionado por el FROB duró 10 días. La venta se adjudicó a CaixaBank por un euro después de recibir 5.500 millones de fondos públicos. El informe de Oliver Wyman de 2012 motivó dicha reanudación. En él se estimaban unas necesidades de 1.846 millones en el escenario base, escenario que ha sido peor que el real.Este trabajo analiza el valor del BdV. Los resultados indican que el valor mínimo del BdV para CaixaBank es de más de 4.000 millones de euros. Sin embargo, no se ha podido determinar el porqué de esta diferencia. Diferencia reconocida en las cuentas de CaixaBank. Sin embargo, el precio pagado, un euro, después de un sacrificio muy impor…

MarketingValoración de empresasEconomics and EconometricsStrategy and Management05 social sciences050201 accountinglcsh:Businessddc:6500502 economics and businessG21G12G34Business and International Managementlcsh:HF5001-6182Company valuation050203 business & managementBanco de ValenciaCaixaBankEuropean Research on Management and Business Economics
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