Search results for "ddc:"
showing 10 items of 3080 documents
De Novo Genome Assembly of the Raccoon Dog (Nyctereutes Procyonoides)
2021
The raccoon dog, Nyctereutes procyonoides (NCBI Taxonomy ID: 34880, Figure 1a) belongs to the family Canidae, with foxes (genus Vulpes) being their closest relatives (Lindblad-Toh et al., 2005; Sun et al., 2019). Its original distribution in East Asia ranges from south-eastern Siberia to northern Vietnam and the Japanese islands. In the early 20th century, the raccoon dog was introduced into Western Russia for fur breeding and hunting purposes, which led to its widespread establishment in many European countries, Figure 1b. Together with the raccoon (Procyon lotor), it is now listed in Europe as an invasive species of Union concern (Regulation (EU) No. 1143/2014) and member states are requi…
European contribution to the study of ROS : A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
2017
WOS: 000410470000009
Requirements Analysis and Specification for a Molecular Tumor Board Platform Based on cBioPortal
2020
Clinicians in molecular tumor boards (MTB) are confronted with a growing amount of genetic high-throughput sequencing data. Today, at German university hospitals, these data are usually handled in complex spreadsheets from which clinicians have to obtain the necessary information. The aim of this work was to gather a comprehensive list of requirements to be met by cBioPortal to support processes in MTBs according to clinical needs. Therefore, oncology experts at nine German university hospitals were surveyed in two rounds of interviews. To generate an interview guideline a scoping review was conducted. For visual support in the second round, screenshot mockups illustrating the requirements …
Modulation of Neocortical Development by Early Neuronal Activity: Physiology and Pathophysiology.
2017
Animal and human studies revealed that patterned neuronal activity is an inherent feature of developing nervous systems. This review summarizes our current knowledge about the mechanisms generating early electrical activity patterns and their impact on structural and functional development of the cerebral cortex. All neocortical areas display distinct spontaneous and sensory-driven neuronal activity patterns already at early phases of development. At embryonic stages, intermittent spontaneous activity is synchronized within small neuronal networks, becoming more complex with further development. This transition is accompanied by a gradual shift from electrical to chemical synaptic transmiss…
PspA adopts an ESCRT-III-like fold and remodels bacterial membranes
2021
Summary PspA is the main effector of the phage shock protein (Psp) system and preserves the bacterial inner membrane integrity and function. Here, we present the 3.6 A resolution cryoelectron microscopy (cryo-EM) structure of PspA assembled in helical rods. PspA monomers adopt a canonical ESCRT-III fold in an extended open conformation. PspA rods are capable of enclosing lipids and generating positive membrane curvature. Using cryo-EM, we visualized how PspA remodels membrane vesicles into μm-sized structures and how it mediates the formation of internalized vesicular structures. Hotspots of these activities are zones derived from PspA assemblies, serving as lipid transfer platforms and lin…
Überlegungen zur Europäisierung an Hochschulen : Möglichkeiten für eine niedrigschwellige (digitale) Mobilität – zwischen sozialen Ungleichheiten und…
2019
The following paper critically discusses the idea of a learning platform for teaching and learning at universities in an international context highlighting several social questions that arise in relation to questions of higher education and mobility. By using the example of the proposed platform, the paper touches on existing social inequalities in a complex system of international university landscapes and current educational and political changes by relating the discussed topics to the Four Freedoms of the European Union, namely the free movement of capital, goods, services and people. Based on the discussion of the ambivalence of benefits and limitations of current changes in higher educ…
Cognitive Biases in Pathological Health Anxiety
2016
Pathological health anxiety refers to the medically unfounded fear of suffering from a severe illness. Differences in cognitive processes related to attention, memory, and evaluation of health threat have been hypothesized to underlie pathological health anxiety. In no study, however, have researchers systematically and simultaneously assessed different cognitive biases. On the basis of the idea that multiple cognitive biases simultaneously contribute to psychopathology (the combined-cognitive-bias hypothesis), we compared 88 patients with pathological health anxiety, 52 patients with depressive disorder, and 52 healthy participants on their performance in several cognitive tasks involving…
Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls &a…
2017
Neuropsychiatric disease and treatment 2017(13), 2621-2630 (2017). doi:10.2147/NDT.S137549
Practices of Writing in Ethnographic Work
2020
Although the practice of writing is key to the production of ethnographic knowledge, the topic remains understudied. Using material from our own ethnographic research in the fields of air travel and cultural heritage as data, we develop a reflexive account of ethnographic writing. We examine in detail the practices of jotting down observations, writing field notes, analytic annotating, ordering and rearranging, and drafting and revising papers. The article takes a praxeological stance, conceptualizing writing as a practice that is simultaneously cognitive, embodied, and material. Our analysis finds that writing influences and shapes all stages of ethnographic work, from orienting perception…
VOT in French as a foreign language : A production and perception study with mono- and multilingual learners (German/Mandarin-Chinese)
2016
This study addresses the production of Voice Onset Time (VOT) in French as a foreign language (FFL). The learners are young multilingual learners who speak Mandarin Chinese as a heritage language along with German. To determine potential effects of the learners’ multilingual background, these multilingual learners were compared to three control groups: (1) monolingual German learners of FFL, (2) monolingual Mandarin Chinese learners of FFL, and (3) native speakers of French (L1). In addition, a perception experiment was carried out to find out to what extent the VOT values measured in the production data contribute to the perception of foreign accent. Our results show that multilingual lear…