Search results for "declaration"
showing 10 items of 115 documents
Assessing the added value of the recent declaration on unregulated fishing for sustainable governance of the central Arctic Ocean
2016
Accepted manuscript version. Published version available at https://doi.org/10.1016/j.marpol.2016.01.013. Accepted manuscript version, licensed CC BY-NC-ND 4.0. The ‘Declaration concerning the prevention of unregulated high seas fishing in the central Arctic Ocean’ signed by the Arctic 5 nations, limits unregulated high seas fishing in the central part of the Arctic Ocean, and holds potential social, economic and political impacts for numerous stakeholders. In this paper, the four Interim Measures in the Declaration are discussed and what value these measures bring beyond the existing international agreements is explored. It is found that even though the Declaration fills a gap in the manag…
Communication about vaccination: A shared responsibility
2016
ABSTRACT Vaccine hesitancy is an important issue to be addressed, due to the risk of decrease of vaccination coverage and consequent control of preventable diseases. While it is not considered a specific determinant, poor or inadequate communication can contribute to vaccine hesitancy and negatively influence vaccination uptake. As a contribution to the ongoing discussion regarding this theme and in the perspective of the implementation of the upcoming national vaccination plan in Italy, the Erice Declaration was drafted by experts in the field of immunization following a 5-day residential, independent workshop regarding communication topics in vaccinology. The aim of the current letter is …
Protein misfolding, amyotrophic lateral sclerosis and guanabenz: Protocol for a phase II RCT with futility design (ProMISe trial)
2017
IntroductionRecent studies suggest that endoplasmic reticulum stress may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS) through an altered regulation of the proteostasis, the cellular pathway-balancing protein synthesis and degradation. A key mechanism is thought to be the dephosphorylation of eIF2α, a factor involved in the initiation of protein translation. Guanabenz is an alpha-2-adrenergic receptor agonist safely used in past to treat mild hypertension and is now an orphan drug. A pharmacological action recently discovered is its ability to modulate the synthesis of proteins by the activation of translational factors preventing misfolded protein accumula…
70 años de la Declaración Universal de Derechos Humanos : introducción a una colección plural de reflexiones | 70 years of the Universal Declaration …
2019
Resumen: Tras una breve reflexión introductoria, este texto presenta algunos de los trabajos derivados del Congreso Internacional sobre el 70 Aniversario de la Declaración Universal de Derechos Humanos, que tuvo lugar en Valencia en diciembre de 2018. Los trabajos se han clasificado en siete secciones: 1) Ponencias invitadas; 2) Violencia de género y derechos de las mujeres; 3) Empresas multinacionales y derechos humanos; 4) Memoria histórica y derechos humanos; 5) Nuevos escenarios y nuevas garantías para los derechos; 6) Contextos y vulnerabilidades; 7) Perspectivas.
 Abstract: After a brief introductory reflection, this text presents some of the works derived from the International …
Los derechos de las personas LGBTI : ¿hacia un derecho a la orientación sexual y la identidad de género?
2020
Este trabajo tiene por objeto un estudio de los derechos de las minorías sexuales en el marco del sistema internacional de derechos humanos. Ni la Declaración Universal de Derechos Humanos, ni los tratados posteriores contemplan un derecho específico que reconozca y asegure una vida digna para el colectivo de personas LGBTI. Este artículo reivindica “un derecho a la orientación sexual y la identidad de género” que proteja la especial situación de estas personas en el mundo. Para ello, se estudia y analiza la labor del Alto Comisionado de Naciones Unidas para los Derechos Humanos y el Consejo de Derechos Humanos de Naciones Unidas y se hace referencia a la doctrina jurisprudencial del Tribun…
La democracia y los derechos universales frente al auge del populismo | Democracy and universal rights against the rise of populism
2019
La democracia y los derechos universales frente al auge del populismo
 Discurso inaugural en el Congreso Internacional por el 70º Aniversario de la Declaración Universal de Derechos Humanos Instituto de Derechos Humanos de la Universidad de Valencia. Del 10 al 12 de diciembre de 2018, Valencia, España
 Democracy and universal rights against the rise of populism
 Opening speech at the International Congress for the 70th Anniversary of the Universal Declaration of Human Rights. Human Rights Institute of the University of Valencia. From December 10 to 12, 2018, Valencia, Spain
Declaration of will of persons with disabilities in the general theory of legal act and the new perspective based on supports. A study of peruvian law
2021
Indexado en Redib La Convención sobre los Derechos de las Personas con Discapacidad ha supuesto, en términos generales, un replanteamiento de la idea de autonomía de la voluntad al reconocer plena capacidad jurídica en todo sujeto con independencia de su discapacidad. Esta nueva realidad viene a modificar el modo de conceptuar e interpretar la declaración de voluntad en la teoría general del acto jurídico, y muy en especial, cuando la capacidad natural de conocer y querer puede venir naturalmente limitada por una discapacidad psíquica o por un estado de coma. La formación interna de la voluntad y su manifestación se vuelve un asunto complejo, sobre todo cuando los apoyos podrían no ser gara…
Redirected EBV-Specific Stem Cell-Memory and Central-Memory CD8+ T Lymphocytes Exhibit Effective and Sustained Antileukemic Immunity to Acute Myeloid…
2014
Abstract Introduction: Adoptive cellular therapy (ACT) of donor-derived cytolytic T lymphocytes (CTL) directed to leukemia or herpesvirus has proven promising to improve antiviral and antileukemic immunity in patients following allogeneic hematopoietic stem cell transplantation (AHSCT). However, durable clinical responses are often hampered by detrimental graft-versus host (GvH) reactivity and limited persistence of transferred, fully differentiated antileukemic effector T cells (TEFF). We thus explored memory and tumoricidal features of in vitro generated EBV-specific stem cell-memory T cells (TSCM) and central-memory T (TCM) cells, T cell-receptor (TCR) redirected to primary acute myeloid…
Conflicting rationales: leader's experienced ethical challenges in community health care for older people.
2017
BACKGROUND Ethical challenges arise in all types of care, and leaders need to be aware of how to resolve these challenges. Healthcare systems tend to be organised around medical conditions, and the patient is often faced with a series of uncoordinated visits to multiple specialties. Ideally, care should be organised around the patient's needs. AIM The purpose of this article was to highlight some ethical challenges perceived by leaders with responsibility for management and service distribution, finance and ensuring quality of community health services for older people. METHOD This study had a qualitative design with a qualitative content analysis of one focus group with six leaders that me…
Does being a Stranger make it Difficult to Cooperate?
2017
AbstractCompetition and cooperation are two somewhat opposed strategies for interpersonal social interaction that help us to achieve both individual and shared goals. The main aim of this study was to explore which type of social interaction (cooperative or competitive) is more stressful in a face-to-face same-sex dyad in healthy young participants (n = 178), considering outcome obtained in these tasks (positive or negative) and sex as moderating variables, and performance of the task alone as a control condition. Salivary cortisol (Csal) was measured in one sample obtained before task and four obtained after the task (+0, +15, +30 and +45 minutes after). Anxiety-state was assessed before a…