Search results for "dehydrodipeptides"

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Michael additions to double bonds of esters of N-protected (s)-phenylalanyldehydroalanine (X-(s)-Phe-ΔAla-OMe) and its phosphonic acid counterpart (X…

2017

Electrophilic addition of amines, thiols and bromide to the double bonds of model dehydrodipeptides and dehydrophosphonodipeptide was studied. The double bond in these two classes of peptides reacted similarly and gave the same products. These results indicate that dehydropeptides are very good candidates as substrates for modifications of peptide side-chains.

chemistry.chemical_classificationphosphonopeptidesdehydrodipeptidesDouble bond010405 organic chemistryElectrophilic additionOrganic Chemistry010402 general chemistry01 natural sciencesBiochemistryMedicinal chemistry0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundchemistryBromideMichael additionMichael reactiondehydrophosphonodipeptides
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