Search results for "dentistry"

showing 10 items of 4518 documents

Vertical Root Fracture initiation in curved roots after root canal preparation : a dentinal micro-crack analysis with LED transillumination

2017

Background One of the causative factors of root defects is the increased friction produced by rotary instrumentation. A high canal curvature may increase stress, making the tooth more susceptible to dentinal cracks. The purpose of this study was to evaluate dentinal micro-crack formation with the ProTaper NEXT and ProTaper Universal systems using LED transillumination, and to analyze the micro-crack generated at the point of maximum canal curvature. Material and Methods 60 human mandibular premolars with curvatures between 30–49° and radii between 2–4 mm were used. The root canals were instrumented using the Protaper Universal® and Protaper NEXT® systems, with the aid of the Proglider® syst…

0301 basic medicineMaximum curvatureMaterials sciencebusiness.industryResearchRoot canalMicro cracksDentistry030206 dentistryTransilluminationmedicine.diseaseCurvature:CIENCIAS MÉDICAS [UNESCO]Operative Dentistry and Endodontics03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureVertical root fractureUNESCO::CIENCIAS MÉDICASmedicineRotary instrumentationbusinessGeneral Dentistry
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Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

2019

ABSTRACT Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-well plates, without the requirement for any further manipulation. Design and Results: Using this system, biofilms of Streptococcus mutans appear to be sugar-dependent and highly resistant to amoxicilin, an antibiotic to which this oral pathogen is highly sensitive in a planktonic state. Saliva, tongue and dental plaque samples were also used as inocula to form multiple-species biofilms. DNA isolation and Illumina sequencing of the biofilms showe…

0301 basic medicineMicrobiology (medical)Fastidious organismSalivamultiple-species biofilmdental plaquemedicine.drug_classMicroorganismAntibioticslcsh:QR1-502real-timeDental plaquebiofilm dynamicslcsh:Microbiologylcsh:Infectious and parasitic diseasesMicrobiologyStreptococcus mutans03 medical and health sciences0302 clinical medicinetongueantibioticmedicinelcsh:RC109-216Dentistry (miscellaneous)PathogenbiologyOral biofilmsChemistryoral biofilmsBiofilm030206 dentistrybiochemical phenomena metabolism and nutritionmedicine.diseasebiology.organism_classificationStreptococcus mutansstreptococcus mutans030104 developmental biologyInfectious Diseasesin vitro modelimpedanceOriginal ArticleJournal of Oral Microbiology
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MTA apical barrier: In vitro study of the use of ultrasonic vibration

2016

Background: The apexification is the first alternative treatment on a permanent tooth when, after a tooth trauma and in the presence of immature apex trauma, pulp necrosis occurs. Many studies have demonstrated the efficacy of mineral trioxide aggregate (MTA) as apical sealing material of choice in these cases, but has a degree of filtration as all other materials. The objective of this study was to analyze the seal ability of MTA on the duct walls in immature teeth unirradicular apexes, using indirect vibration. Material and Methods: The study was conducted on 45 teeth divided into 3 groups: Group A or control group in which no vibration for placing the MTA was used, Group B and C or group…

0301 basic medicineMineral trioxide aggregateMateriales dentalesDentistryOdontologíaUltrasonidos en medicinaOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicinestomatognathic systemUltrasonic vibrationIn vitro studyTecnología médicaGeneral DentistryPulp necrosisPermanent toothChemistrybusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludAlternative treatmentstomatognathic diseases030104 developmental biologyUNESCO::CIENCIAS MÉDICASApexificationbusinessJournal of Clinical and Experimental Dentistry
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Vertical root fracture resistance of simulated immature permanent teeth filled with MTA using different vehicles

2017

Background The aim of the study is to evaluate the resistance vertical root fracture (VRF) of mineral trioxide aggregate (MTA) filled-immature permanent roots by using three different vehicles. Material and Methods Forty-extracted human single-rooted mandibular premolars were selected and the root length was standardized to the length of 9 mm. For simulation of immature tooth apices, peeso reamers were introduced into the root canals and the prepared roots were assigned into three experimental groups according the used vehicle (distilled water-DW, prophylene glycol-PG, chlorhexidine-CHX) and control group (n=10). To simulate a periodontal membrane, the apical 7 mm of all roots was covered w…

0301 basic medicineMineral trioxide aggregateMaterials scienceDentistryOdontologíaOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicineVertical root fractureFlexural strengthmedicineStatistical analysisGeneral DentistryPermanent teethUniversal testing machinebusiness.industryResearch030206 dentistryTooth Apexmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la salud030104 developmental biologyUNESCO::CIENCIAS MÉDICASFracture (geology)business
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Evaluation of cytocompatibility of calcium silicate-based endodontic sealers and their effects on the biological responses of mesenchymal dental stem…

2015

Aim To investigate in vitro the cytocompatibility of the calcium silicate-containing endodontic sealers MTA Fillapex and TotalFill BC Sealer on human periodontal ligament stem cells (hPDLSCs) by assaying their biological responses and compare them with that observed when using an epoxy resin-based sealer (AH Plus). Methodology Specimens from the three different endodontic sealers were eluated with culture medium for 24 h. The cytotoxicity of these eluates was evaluated using the MTT assay. In addition, an in vitro scratch wound healing model was used to determine their effects on cell migration. Cell adhesion to collagen type I after treatment with the different sealer eluates was also meas…

0301 basic medicineMineral trioxide aggregateMaterials sciencePeriodontal ligament stem cellsCell SurvivalPeriodontal LigamentCell morphologyAndrologyRoot Canal Filling Materials03 medical and health sciences0302 clinical medicineCell MovementMaterials TestingCell AdhesionHumansMTT assayCytotoxicityGeneral DentistryCells CulturedCell ProliferationCell growthSilicatesStem CellsMesenchymal stem cell030206 dentistryAdhesionCalcium Compounds030104 developmental biologyBiomedical engineeringInternational endodontic journal
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The effects of silver nanoparticles on antimicrobial activity of ProRoot mineral trioxide aggregate (MTA) and calcium enriched mixture (CEM)

2016

Background: Although, mineral trioxide aggregate (MTA) and new experimental cement (CEM) are good root filling cements, but had no or low antimicrobial activities. The aim of this study was to evaluate the effects of addition of silver nanoparticles (SNP) to these two cements on antimicrobial effects against five most dental infection related microorganisms. Material and Methods: Two suspensions of 100 and 200 ppm of SNP were prepared and 180 μl of microbial suspension with 1.5 × 10 8 CFU/ml of each respected microorganisms were re-suspended in deionized water or each of SNP suspensions. After that, 60 μg of MTA and CEM were added to each tube. In one tube, the mixture of all above mentione…

0301 basic medicineMineral trioxide aggregateMicroorganismDentistryOdontologíaEnterococcus faecalisSilver nanoparticleAgar plate03 medical and health sciences0302 clinical medicineBiomaterials and Bioengineering in DentistryFood scienceGeneral DentistryCementbiologybusiness.industryChemistryResearch030206 dentistrybiology.organism_classificationAntimicrobial:CIENCIAS MÉDICAS [UNESCO]Ciencias de la salud030104 developmental biologyUNESCO::CIENCIAS MÉDICASAntibacterial activitybusiness
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Effect of Smear Clear and Some Other Commonly Used Irrigants on dislodgement resistance of Mineral Trioxide Aggregate to Root Dentin

2016

Background This study aimed to assess the push-out bond strength of mineral trioxide aggregate (MTA) to root canal dentin after irrigation with Smear Clear in comparison with 2.5% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX) and saline as commonly used root canal irrigants. Material and Methods The coronal and mid-root areas of maxillary anterior teeth were horizontally sectioned into one-millimeter thick slices. The root canal lumen of dentinal slices was dilated using a diamond bur with 1.3 mm diameter. After the application of MTA, the samples were incubated in 100% humidity for 10 minutes and were then randomly divided into four groups (n=20) and immersed in Smear Clear, 2.5% NaO…

0301 basic medicineMineral trioxide aggregateRoot canalDentistryOperative Dentistry and Endodontics03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDentinmedicineGeneral DentistryAnterior teethUniversal testing machineBond strengthbusiness.industryResearchChlorhexidine030206 dentistry:CIENCIAS MÉDICAS [UNESCO]030104 developmental biologymedicine.anatomical_structurechemistrySodium hypochloriteUNESCO::CIENCIAS MÉDICASbusinessmedicine.drugJournal of Clinical and Experimental Dentistry
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Relationship between internal root resorption and dens in dente

2020

Background The aim is to report the treatment and follow-up of three lateral incisors with internal root resorption and dens in dente as a possible cause for their development, managed by root canal treatment and apical obturation with MTA or gutta-percha. Case description This case report presents three clinical cases in which dens invaginatus type 2 is shown as a potential cause for the development of internal root resorption. Two cases were filled with a MTA apical plug technique and one with gutta-percha, and all were follow-up through time. Practical implications The incidence of the association of internal root resorption with dens invaginatus may be underestimated and should be studi…

0301 basic medicineMineral trioxide aggregateRoot canaleducationOdontologíaCase ReportRoot resorptionOperative Dentistry and EndodonticsApical plug03 medical and health sciencesDens invaginatus0302 clinical medicineCirugíamedicineTecnología médicaGeneral DentistryPractical implicationsOrthodonticsbusiness.industry030206 dentistryCase descriptionmedicine.disease:CIENCIAS MÉDICAS [UNESCO]030104 developmental biologymedicine.anatomical_structureUNESCO::CIENCIAS MÉDICASbusinessJournal of Clinical and Experimental Dentistry
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Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials

2017

Human dental pulp stem cells (HDPSCs) are of special relevance in future regenerative dental therapies. Characterizing cytotoxicity and genotoxicity produced by endodontic materials is required to evaluate the potential for regeneration of injured tissues in future strategies combining regenerative and root canal therapies. This study explores the cytotoxicity and genotoxicity mediated by oxidative stress of three endodontic materials that are widely used on HDPSCs: a mineral trioxide aggregate (MTA-Angelus white), an epoxy resin sealant (AH-Plus cement), and an MTA-based cement sealer (MTA-Fillapex). Cell viability and cell death rate were assessed by flow cytometry. Oxidative stress was m…

0301 basic medicineMineral trioxide aggregatelcsh:Internal medicineArticle SubjectDNA damageDentistrymedicine.disease_cause03 medical and health sciences0302 clinical medicineDental pulp stem cellsmedicineViability assaylcsh:RC31-1245Molecular Biologybusiness.industryChemistryRegeneration (biology)030206 dentistryCell Biology030104 developmental biologyCell cultureCancer researchbusinessGenotoxicityOxidative stressResearch ArticleStem Cells International
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Antibacterial potency and fluoride release of a glass ionomer restorative material containing different concentrations of natural and chemical produc…

2018

Background This study investigated the antibacterial efficacy against Streptococcus mutans and fluoride release of a conventional glass ionomer (GI) contained natural and chemical agents. Material and methods Two hundred and ten GI specimens were divided into ten groups (n=21) according to the concentrations of the additives as; Propolis extract containing GI (Groups 1, 2, 3) with concentrations of 0.25%, 0.75% and 1.25% respectively, Miswak extract containing GI (Groups 4, 5, 6) and Chlorhexidine containing GI (Groups 7, 8, 9) with the same concentrations. The prepared specimens were subjected to antimicrobial activity by well diffusion, bacterial adherence, and fluoride release (from 2 to…

0301 basic medicineMiswakChlorhexidineGlass ionomer cement030206 dentistryPropolisAntimicrobial:CIENCIAS MÉDICAS [UNESCO]03 medical and health scienceschemistry.chemical_compound030104 developmental biology0302 clinical medicinechemistryUNESCO::CIENCIAS MÉDICASmedicinePotencyFood scienceAntibacterial activityGeneral DentistryFluoridemedicine.drug
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