Search results for "desat1"

showing 3 items of 3 documents

INHIBITION OF FATTY ACID DESATURASES INDrosophila melanogasterLARVAE BLOCKS FEEDING AND DEVELOPMENTAL PROGRESSION

2016

International audience; Fatty acid desaturases are metabolic setscrews. To study their systemic impact on growth in Drosophila melanogaster, we inhibited fatty acid desaturases using the inhibitor CAY10566. As expected, the amount of desaturated lipids is reduced in larvae fed with CAY10566. These animals cease feeding soon after hatching, and their growth is strongly attenuated. A starvation program is not launched, but the expression of distinct metabolic genes is activated, possibly to mobilize storage material. Without attaining the normal size, inhibitor-fed larvae molt to the next stage indicating that the steroid hormone ecdysone triggers molting correctly. Nevertheless, after moltin…

Fatty Acid Desaturases0301 basic medicinePhysiologymedicine.medical_treatmentMoltingBiochemistrychemistry.chemical_compound0302 clinical medicinehomeostasisDrosophila Proteins2. Zero hungerchemistry.chemical_classificationsex-pheromonesGene Expression Regulation DevelopmentalGeneral Medicineinsulin-like peptidesAmino acidDrosophila melanogastersynthaseBiochemistryLarvaDrosophila melanogasterMoultingEcdysoneEcdysoneinsulinanimal structuresgrowthamino-acidsBiologylipids03 medical and health sciencesdesat1medicineAnimals[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologydevelopment[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular Biologystearoyl-coa desaturase-1fungiFatty acidFeeding Behaviorbiology.organism_classificationgene-expressionSteroid hormone030104 developmental biologyEnzymechemistryInsect SciencecellsStearoyl-CoA desaturase-1030217 neurology & neurosurgeryArchives of Insect Biochemistry and Physiology
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Gene Regulation and Species-Specific Evolution of Free Flight Odor Tracking in Drosophila

2018

Running title: flight evolution in Drosophila This is an invited contribution to the special issue on Genetics of Adaptation based on a symposium of the same name at the National Centre for Biological Sciences (TIFR, Bangalore, India) in November 2016; International audience; The flying ability of insects has coevolved with the development of organs necessary to take-off from the ground, generate, and modulate lift during flight in complex environments. Flight orientation to the appropriate food source and mating partner depends on the perception and integration of multiple chemical signals. We used a wind tunnel-based assay to investigate the natural and molecular evolution of free flight …

Fatty Acid DesaturasesMale0301 basic medicineFat bodymelanogastercoordinationD. buzzatiiconsequencesReceptors OdorantPheromonesD. suzukiifliesDrosophila ProteinsGene Regulatory Networksfat bodyMatingRegulation of gene expressionbiologysex-pheromonesAnatomyBiological EvolutionoenocytemodulationDrosophilaFemaleFree flightZimbabweGenetic SpeciationsystemD. virilisEvolution Molecular03 medical and health sciencesSex FactorsSpecies Specificitydesaturase geneMolecular evolutiondesat1expressionGeneticsAnimalsMolecular BiologyDrosophilaGeneEcology Evolution Behavior and Systematics[SDV.GEN]Life Sciences [q-bio]/Geneticsfungibiology.organism_classification030104 developmental biologyGene Expression RegulationOdorEvolutionary biologyFlight Animalsexual dimorphismOdorants[ SDV.GEN ] Life Sciences [q-bio]/Genetics
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Peripheral, central and behavioral responses to the cuticular pheromone bouquet in Drosophila melanogaster males.

2011

International audience; Pheromonal communication is crucial with regard to mate choice in many animals including insects. Drosophila melanogaster flies produce a pheromonal bouquet with many cuticular hydrocarbons some of which diverge between the sexes and differently affect male courtship behavior. Cuticular pheromones have a relatively high weight and are thought to be -- mostly but not only -- detected by gustatory contact. However, the response of the peripheral and central gustatory systems to these substances remains poorly explored. We measured the effect induced by pheromonal cuticular mixtures on (i) the electrophysiological response of peripheral gustatory receptor neurons, (ii) …

MaleOlfactory systemTasteAnatomy and PhysiologyINSECTSPERIPHERAL GUSTATORY RECEPTOR NEURONSlcsh:MedicinePheromonesAnimals Genetically ModifiedBehavioral Neuroscience0302 clinical medicineTaste receptorCUTICULAR PHEROMONE BOUQUETANOSMIC MALESlcsh:Science0303 health sciencesMultidisciplinaryBehavior AnimalbiologyBrainAnimal ModelsNeuroethologyOlfactory PathwaysAnatomyMUTANT DESAT1 MALESElectrophysiologyMate choiceMALESTasteSex pheromonePheromoneSensory PerceptionFemaleDROSOPHILA MELANOGASTER[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Drosophila melanogasterResearch Articlemedicine.medical_specialtyEndocrine SystemPHEROMONAL COMMUNICATION03 medical and health sciencesModel OrganismsInternal medicinemedicineAnimalsBiologyCUTICULAR HYDROCARBONS030304 developmental biologyEndocrine PhysiologyCourtship displaylcsh:Rbiology.organism_classificationPHEROMONAL PERCEPTIONEndocrinologyGUSTATORY CONTACT[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]CALCIUM VARIATIONDROSOPHILA MELANOGASTER;MALES;CUTICULAR PHEROMONE BOUQUET;PHEROMONAL COMMUNICATION;INSECTS;CUTICULAR HYDROCARBONS;GUSTATORY CONTACT;PERIPHERAL GUSTATORY RECEPTOR NEURONS;CALCIUM VARIATION;MUTANT DESAT1 MALES;ANOSMIC MALES;PHEROMONAL PERCEPTIONCalciumlcsh:Q030217 neurology & neurosurgeryNeuroscience
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