Search results for "design."
showing 10 items of 5715 documents
The rise of the middle author: Investigating collaboration and division of labor in biomedical research using partial alphabetical authorship
2017
Contemporary biomedical research is performed by increasingly large teams. Consequently, an increasingly large number of individuals are being listed as authors in the bylines, which complicates the proper attribution of credit and responsibility to individual authors. Typically, more importance is given to the first and last authors, while it is assumed that the others (the middle authors) have made smaller contributions. However, this may not properly reflect the actual division of labor because some authors other than the first and last may have made major contributions. In practice, research teams may differentiate the main contributors from the rest by using partial alphabetical author…
Procedimento estratégico em três estágios de seleção de variáveis para a obtenção de resultados equilibrados na pesquisa em saúde pública
2018
Multidisciplinary research in public health is approached using methods from many scientific disciplines. One of the main characteristics of this type of research is dealing with large data sets. Classic statistical variable selection methods, known as “screen and clean”, and used in a single-step, select the variables with greater explanatory weight in the model. These methods, commonly used in public health research, may induce masking and multicollinearity, excluding relevant variables for the experts in each discipline and skewing the result. Some specific techniques are used to solve this problem, such as penalized regressions and Bayesian statistics, they offer more balanced results a…
Assessing autophagy in archived tissue or how to capture autophagic flux from a tissue snapshot
2020
This article belongs to the Special Issue Autophagy in Cancer.
A novel device for intracolonoscopy cleansing of inadequately prepared colonoscopy patients: a feasibility study.
2019
Abstract Background The importance of high quality preprocedural bowel preparation is widely acknowledged, but suboptimal bowel cleansing still occurs in up to 20 % of all colonoscopy patients. The aim of this study was to evaluate the performance of a novel intraprocedural cleaning device for cleaning poorly prepared colons. Methods This multicenter feasibility study included patients aged 18 – 75 years who were referred for colonoscopy. Intraprocedural cleaning was performed in patients after a limited preprocedural bowel preparation regimen (2 days of dietary restrictions and 2 × 10 mg bisacodyl). The primary outcome was the proportion of adequately prepared patients (Boston Bowel Prepar…
On the Statistical Properties of Capacity Outage Intervals in OSTBC-MIMO Rayleigh Fading Channels
2016
This paper deals mainly with the study of the asymptotic probability density functions (PDFs) of the outage durations of the instantaneous capacity of orthogonal space-time block code (OSTBC) multiple-input multiple-output (MIMO) systems over Rayleigh channels. Drawing upon known statistical properties for the asymptotic behavior of chi-squared processes at low levels, we provide approximate solutions for the PDF, the cumulative distribution function (CDF), and the $k$ th-order moments of the outage intervals of the underlying capacity processes. Then, as an application of the derived PDF, the performance assessment of capacity simulators is reported. Following this, we introduce the newly …
Bollettino di Matematica pura e applicata
2020
The paper emphasizes some the advances of knowledge in mathematics problems ad new applications. The Bollettino is open to the contribution of Italian or foreign researchers.
Examples of additive designs
2012
In this paper we present some additive designs.
On the representations in GF(3)^4 of the Hadamard design H_11
2020
In this paper we study the representations of the 2-(11,5,2) Hadamard design H_11 = (P,B) as a set of eleven points in the 4-dimensional vector space GF(3)^4, under the conditions that the five points in each block sum up to zero, and dim ‹P› = 4. We show that, up to linear automorphism, there exist precisely two distinct, linearly nonisomorphic representations, and, in either case, we characterize the family S of all the 5-subsets of P whose elements sum up to zero. In both cases, S properly contains the family of blocks B, thereby showing that a previous result on the representations of H_11 in GF(3)^5 cannot be improved.
Effects of a Mediterranean Eating Plan on the Need for Glucose-Lowering Medications in Participants With Type 2 Diabetes: A Subgroup Analysis of the …
2019
OBJECTIVE: To examine the effects of two Mediterranean eating plans (Med-EatPlans) versus a low-fat eating plan on the need for glucose-lowering medications. RESEARCH DESIGN AND METHODS: From the Prevención con Dieta Mediterránea (PREDIMED) trial, we selected 3,230 participants with type 2 diabetes at baseline. These participants were randomly assigned to one of three eating plans: Med-EatPlan supplemented with extra-virgin olive oil (EVOO), Med-EatPlan supplemented with mixed nuts, or a low-fat eating plan (control). In a subgroup (15%), the allocation was done in small clusters instead of using individual randomization, and the clustering effect was taken into account in the statistical a…
Obesity interferes with the orosensory detection of long-chain fatty acids in humans
2014
Background: The association between the orosensory detection of lipids, preference for fatty foods, and body mass index (BMI; in kg/m 2 ) is controversial in humans. Objective: We explored the oral lipid-sensing system and the orosensory-induced autonomic reflex system in lean and obese subjects. Design: Lean (BMI: 19 to ,25; n = 30) and obese (BMI .30; n = 29) age-matched men were enrolled. Their oral threshold sensitivity to linoleic acid (LA) was determined by using a 3-alternative forced-choice ascending procedure, and their eating habits were established by the analysis of 4 consecutive 24-h food-consumption diaries. The effect of brief oral lipid stimulations on plasma triglyceride [(…