Search results for "development."
showing 10 items of 26708 documents
Global urban environmental change drives adaptation in white clover
2022
Made available in DSpace on 2022-04-28T19:52:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-18 Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied am…
Population divergence in maternal investment and embryo energy use and allocation suggests adaptive responses to cool climates
2023
1. The thermal sensitivity of early life stages can play a fundamental role in constraining species distributions. For egg-laying ectotherms, cool temperatures often extend development time and exacerbate developmental energy cost. Despite these costs, egg laying is still observed at high latitudes and altitudes. How embryos overcome the developmental constraints posed by cool climates is crucial knowledge for explaining the persistence of oviparous species in such environments and for understanding thermal adaptation more broadly. 2. Here, we studied maternal investment and embryo energy use and allocation in wall lizards spanning altitudinal regions, as potential mechanisms that enable su…
Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and rela…
2016
A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidene)butanoate as an example of a new class of sortase A inhibitors. Other analogues were generated by changing the ethoxycarbonyl function for a carboxy, cyano or amide group, or introducing substituents in the phenyl ring of the ester and acid derivatives. The most active derivative found was 3-oxo-2-(2-(3,4dichlorophenyl)hydrazinylidene)butanoic acid (2b), showing an IC50 value of 50 µM. For a preliminary assessment of their antivirulence properties the new derivatives were tested for their antibiofilm activity. The most active compo…
Living the urban challenge : sustainable development and social sustainability in two southern megacities
2007
Kehitysmaiden nopea kaupungistuminen ja miljoonakaupunkien voimakas kasvu luovat haasteita kestävään kehitykseen tähtäävälle suunnittelulle. Kansainvälisissä kehitysohjelmissa on pyritty turvaamaan suurkaupunkien taloudelliset ja ympäristölliset tavoitteet. Kestävän kehityksen sosiaalinen ulottuvuus on usein rajattu kaupunkien tarjoamiin sosiaalipalveluihin.- Ympäristön säilyttäminen tuleville sukupolville ei onnistu vain talouteen, ympäristöön ja palveluihin kohdistuvilla teknisillä toimilla. Tämä johtuu etelän suurkaupungeille tyypillisestä räikeästä sosiaalisesta eriarvoisuudesta. Suurkaupunkien suunnittelussa tulisi analysoida sellaisia sosiaalisia haasteita, jotka heikentävät kaupunkie…
Constructing social Europe through European cultural heritage
2021
The political and economic crises of the recent decades as well as the new changes brought on by globalization and digitalization have contributed to exacerbate social inequalities and injustice and revealed different social realities in Europe. The EU increasingly deals with social issues in its cultural and heritage policy. In this article, we explore the construction of this social dimension and advance the concept of 'social Europe' by exploring its cultural aspect based on our analysis of a recent EU heritage action, the European Heritage Label. In this action, the narrations of the European past and the attempts to foster common cultural heritage in Europe function as building blocks …
Striving to strengthen the ecosocial framework in social work in Finland
2021
AbstractThere is no economic or social sustainability without ecological sustainability, yet the latter can hardly be achieved without the other forms of sustainability. While contemporary consumer societies are still today fundamentally unsustainable, advancing the overall sustainability transition as well as mitigating and preventing the ecological crisis should be high on the social work and community development agendas. On one hand, this is because the ecological crisis both causes and increases social inequality and vulnerability. On the other hand, aspiring sustainability requires profound social and cultural changes, bringing about which belongs to social work and community work’s a…
Nuorten urheilupolut : tutkimus kilpaurheiluun sosiaalistumisen normeista, pääomista ja toimijuudesta
2016
Sport is a popular activity among Finnish children and adolescents. Junior sport encompasses various objectives, and one of its functions is to generate the prerequisites for competitive sport and an elite sports career. This study examines socialization into competitive sport. It approaches the socialization process as a sports path that denotes the sequence of states and events in sport as part of one’s life course. The study emphasizes experiences and through them the meaning-giving and lifeworld of the young athletes themselves. Hence, the aim of the study is to create a sociological interpretation of athlete development. The research data comprise a survey of 2,430 registered participa…
EFL Teacher Education in Finland : Manifestations of Professional Agency in Teacher Educators’ Work
2020
English as a Foreign Language (EFL) teacher educators play a key role in the development of university-based teacher education and the preparation of preservice EFL teachers. However, the professional agency of EFL teacher educators in developing their work remains understudied. Employing a Vygotskian sociocultural theoretical perspective, this research considers the individual and collective professional agency of eight EFL teacher educators at two Finnish universities. Findings demonstrate that individual professional agency is enacted in the expression of professional identity and the development of professional relationships, and in offering and receiving professional assistance. Findin…
Data practices and inequality in South African early childhood development policy: Technocratic management versus social transformation
2019
Background: In 1994, the African National Congress identified early childhood development as a potential strategy to redress the inequalities of apartheid, however, two and a half decades later, poverty still persists, and South Africa is one of the most unequal countries in the world. Aim: This article explores how policy texts based on and with the use of certain data practices establish ‘truths’ about childhoods and society, construct families and communities, and determine forms of provision to address inequality. Setting: In 2015, the South African government published the National Integrated Early Childhood Policy (NIECDP) to continue to address poverty and inequality. Its implementat…
Hierarchies of knowledge, incommensurabilities and silences in South African ECD policy: Whose knowledge counts?
2017
AbstractPolicy for young children in South Africa is now receiving high-level government support through the ANC’s renewed commitment to redress poverty and inequity and creating ‘a better life for all’ as promised before the 1994 election. In this article, I explore the power relations, knowledge hierarchies and discourses of childhood, family and society in National Curriculum Framework (NCF) as it relates to children’s everyday contexts. I throw light on how the curriculum’s discourses relate to the diverse South African settings, child rearing practices and world-views, and how they interact with normative discourses of South African policy and global early childhood frameworks. The NCF…