Search results for "diagnostic"

Inflammatory response elements, glycan, and proteome profiles as salivary biomarkers for the early diagnosis of OSCC

2021

El cáncer oral, sobre todo el, carcinoma oral de células escamosas (COCE), es la neoplasia maligna más común en la cavidad oral que se caracteriza por un mal pronóstico y una baja tasa de supervivencia, cuando se diagnostica en estadios avanzados. Puede ser tratado de forma efectiva si se detecta en estadios iniciales, mejorando el pronóstico. Por tanto, tras la prevención, el diagnóstico precoz se ha convertido en el principal objetivo en el manejo del cáncer oral, dado su impacto positivo en la supervivencia y calidad de vida de estos pacientes. A menudo, los escasos síntomas iniciales pasan desapercibidos y la enfermedad se descubre en fases avanzadas, por lo que se requiere mejorar el d…

Advances in the endoscopic management of malignant biliary obstruction

2020

Biliary obstruction is common in pancreatobiliary malignancies and has a negative impact on the patient’s quality of life, postoperative complications, and survival rates. Particularly in the last decade, there has been enormous progress regarding the diagnostic and therapeutic options in patients with malignant biliary obstruction. Endoscopy has given a new insight in this direction and novel techniques have been developed for the better characterization and treatment of malignant strictures. We herein summarize the available data on the different endoscopic techniques, and clarify their role in the diagnosis and treatment of malignant biliary obstructive disease. Finally, we propose an al…

The structure of coronal plasma in active stellar coronae from density measurements

2005

We have analyzed high-resolution X-ray spectra of a sample of 22 active stars observed with the High Energy Transmission Grating Spectrometer (HETGS) on Chandra in order to investigate their coronal plasma density, using the lines of the He-like ions O VII, Mg XI, and Si XIII. Si XII lines in all stars of the sample axe compatible with the low-density limit (i.e. n(e) = 10(30) erg/s); O VII lines yield much lower densities of a few 10(10) cm(-3). Our results indicate that the "hot" and "cool" plasma resides in physically different structures. Our findings imply remarkably compact coronal structures, especially for the hotter (similar to 7 MK) plasma emitting the Mg xi lines characterized by…

Mental Skills of an Athlete as a Resource of Professional Longevity in Sport

2021

The aim of the study was to assess associations between dimensions of mental skills, psychological readiness and predictors of career longevity among current athletes. Mental skills dimensions were measured with the Ottawa Mental Skills Assessment Tool (OMSAT). The psychological predictors of athletic career longevity were measured with the Athletic Coping Skills Scale-28 (the ACSI-28) producing scores for seven coping skills and with the Competitive State Anxiety Inventory-2 (CSAI-2) which produced scores for confidence in competition. Overall, 253 current athletes (average age 22 years) of various competitive levels (classified to 5 groups according to the national sport classification sy…

The value of synthetic linear epitope analogues of La/SSB for the detection of autoantibodies to La/SSB; specificity, sensitivity and comparison of m…

1998

SUMMARY In a previous study it was shown that La/SSB contains four linear epitopes, p147–154, p291–302, p301–318 and p349–364. The aim of the present study was to investigate the value of the synthetic epitope analogues of the La/SSB autoantigen for the detection of antibodies to La/SSB, in comparison with recombinant La and fragments of this protein. A total of 122 sera with anti-La/SSB activity, from patients with primary Sjögren's syndrome (pSS) or systemic lupus erythematosus (SLE), were tested in various peptide-based assays. In addition, 62 sera from pSS or SLE patients with other autoantibody specificities and 95 sera from healthy individuals were used as controls. The autoantibody s…

Exploiting ongoing EEG with multilinear partial least squares during free-listening to music

2016

During real-world experiences, determining the stimulus-relevant brain activity is excitingly attractive and is very challenging, particularly in electroencephalography. Here, spectrograms of ongoing electroencephalogram (EEG) of one participant constructed a third-order tensor with three factors of time, frequency and space; and the stimulus data consisting of acoustical features derived from the naturalistic and continuous music formulated a matrix with two factors of time and the number of features. Thus, the multilinear partial least squares (PLS) conforming to the canonical polyadic (CP) model was performed on the tensor and the matrix for decomposing the ongoing EEG. Consequently, we …

Determining the number of sources in high-density EEG recordings of event-related potentials by model order selection

2011

To high-density electroencephalography (EEG) recordings, determining the number of sources to separate the signal and the noise subspace is very important. A mostly used criterion is that percentage of variance of raw data explained by the selected principal components composing the signal space should be over 90%. Recently, a model order selection method named as GAP has been proposed. We investigated the two methods by performing independent component analysis (ICA) on the estimated signal subspace, assuming the number of selected principal components composing the signal subspace is equal to the number of sources of brain activities. Through examining wavelet-filtered EEG recordings (128…

An Atypical Case of Taravana Syndrome in a Breath-Hold Underwater Fishing Champion: A Case Report

2013

Dysbaric accidents are usually referred to compressed air-supplied diving. Nonetheless, some cases of decompression illness are known to have occurred among breath-hold (BH) divers also, and they are reported in the medical literature. A male BH diver (57 years old), underwater fishing champion, presented neurological disorders as dizziness, sensory numbness, blurred vision, and left frontoparietal pain after many dives to a 30–35 meters sea water depth with short surface intervals. Symptoms spontaneously regressed and the patient came back home. The following morning, pain and neurological impairment occurred again and the diver went by himself to the hospital where he had a generalized to…

Trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS): preliminary Italian (and world-first) experience at 1,5 Tesla (first 5 patient treate…

2015

Chirurgia trans-cranica mediante ultrasuoni focalizzati ad alta intensità su guida RM: esperienza preliminare a 1,5T (prima paziente trattata)

2015

Presentiamo i risultati preliminari ottenuti con la prima istallazione italiana di un’apparecchiatura per la neurochirurgia funzionale mediante ultrasuoni focalizzati ad alta intensità su guida RM (trans-cranial MRI-guided Focused Ultrasound Surgery, tcMRgFUS); si tratta tra l’altro della prima apparecchiatura tcMRgFUS al mondo mai installata su uno scanner RM da 1,5T. Tale apparecchiatura è destinata a trattamenti di neurochirurgia funzionale di pazienti con tremore essenziale (Essential Tremor, ET), Parkinson idiopatico (Parkinson Disease, PD) prevalentemente tremorigeno e dolore neuropatico (Neuropa- thic Pain, NP). Sanno presentati i risultati ottenuti con i primi pazienti sottoposti …