Search results for "diethylenetriamine"

showing 10 items of 50 documents

CCDC 188644: Experimental Crystal Structure Determination

2003

Related Article: I.Muga, J.M.Gutierrez-Zorrilla, P.Vitoria, P.Roman, F.Lloret|2002|Polyhedron|21|2631|doi:10.1016/S0277-5387(02)01240-8

(mu~2~-Oxalato)-bis(mu~2~-cyano)-bis(diethylenetriamine-nickel(ii))-dicyano-platinumSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Development of a simple, biocompatible and cost-effective Inulin-Diethylenetriamine based siRNA delivery system

2015

Small interfering RNAs (siRNAs) have the potential to be of therapeutic value for many human diseases. So far, however, a serious obstacle to their therapeutic use is represented by the absence of appropriate delivery systems able to protect them from degradation and to allow an efficient cellular uptake. In this work we developed a siRNA delivery system based on inulin (Inu), an abundant and natural polysaccharide. Inu was functionalized via the conjugation with diethylenetriamine (DETA) residues to form the complex Inu-DETA. We studied the size, surface charge and the shape of the Inu-DETA/siRNA complexes; additionally, the cytotoxicity, the silencing efficacy and the cell uptake-mechanis…

3003Small interfering RNAJHH6CellPharmaceutical ScienceEndocytosisCell LineIn vivoCell Line TumormedicinePolyaminesGene silencingHumansMicropinocytosisRNA Small InterferingCytotoxicityChemistry16HBEInulinEndocytosisDiethylenetriamine (DETA)Cell biologyInu-DETA copolymermedicine.anatomical_structureBiochemistryCytoplasmSettore CHIM/09 - Farmaceutico Tecnologico ApplicativosiRNA16HBE; Diethylenetriamine (DETA); Inu-DETA copolymer; Inulin; JHH6; siRNA; 3003E2F1 Transcription Factor
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Stabilities and coordination modes of histidine in copper(II) mixed-ligand complexes with ethylenediamine, diethylenetriamine or N,N,N′,N″,N″-pentame…

2008

Abstract Solution equilibrium studies on the Cu(II)–polyamine–methionine ternary systems (polyamine: ethylenediamine (en), diethylenetriamine (dien), N,N,N′,N′′,N′′-pentamethyldiethylenetriamine (Me5dien)) have been performed by pH-potentiometry, UV–Vis spectrophotometry and EPR methods. The obtained results suggest the formation of the mixed-ligand complexes with [Cu(A)(Met)]+ stoichiometry in all studied systems. Our spectroscopic results indicate the tetragonal geometry for [Cu(en)(Met)]+, the geometry slightly deviated from square pyramidal for [Cu(dien)(Met)]+ and strongly deviated from square pyramidal towards trigonal bipyramidal for the [Cu(Me5dien)(Met)]+ species. The coordination …

Aqueous solutionChemistryInorganic chemistrychemistry.chemical_elementEthylenediamineCopperSquare pyramidal molecular geometrylaw.inventionInorganic ChemistryTrigonal bipyramidal molecular geometrychemistry.chemical_compoundCrystallographylawDiethylenetriamineMaterials ChemistryPhysical and Theoretical ChemistryElectron paramagnetic resonanceTernary operationPolyhedron
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Sequestration of alkyltin(IV) cations by complexation with amino-polycarboxylic chelating agents

2013

Abstract The binding capacity of four amino-polycarboxylic ligands (APCs) [nitrilotriacetate (NTA), ethylenediamine- N , N , N′ , N′ -tetraacetate (EDTA), (S,S)-ethylenediamine- N , N ′-disuccinic acid (S,S-EDDS) and diethylenetriamine- N , N , N′ , N″ , N″ -pentaacetate (DTPA)] towards mono-, di- and tri-alkyltin(IV) cations [(CH 3 )Sn 3 + , (CH 3 ) 2 Sn 2 + , (C 2 H 5 ) 2 Sn 2 + , (CH 3 ) 3 Sn + or (C 2 H 5 ) 3 Sn + ] was studied, in aqueous solutions, by ISE-H + potentiometry, at I  = 0.1 mol L − 1 (NaCl) and at T  = 298.15 K. In all the systems R x Sn (4 − x)+  − APC (R = CH 3 or C 2 H 5 ) a strong 1:1 species is formed together with protonated, hydroxo and dinuclear complexes. The valu…

Aqueous solutionComplexation in aqueous solutionStereochemistryLigandEthylenediamineProtonationAlkyltin(IV) cations; Amino-polycarboxylic ligands; Complexation in aqueous solution; Sequestration ability of complexones;Condensed Matter PhysicsMedicinal chemistryAtomic and Molecular Physics and OpticsAlkyltin(IV) cationElectronic Optical and Magnetic MaterialsIonAmino-polycarboxylic ligandchemistry.chemical_compoundSequestration ability of complexoneschemistryDiethylenetriamineMaterials ChemistryChelationSettore CHIM/01 - Chimica AnaliticaPhysical and Theoretical ChemistrySimple correlationSpectroscopy
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Stabilities and Coordination Modes of α-Alaninephosphonic Acid in Copper(II) Heteroligand Complexes with Ethylenediamine, Diethylenetriamine or N,N,N…

2011

Solution equilibrium studies on Cu2+–L1–L2 ternary systems have been performed by pH-potentiometry, UV–Vis spectrophotometry and EPR methods (L1 corresponds to polyamines such as ethylenediamine (en), diethylenetriamine (dien), or N,N,N′,N′,N″-pentamethyldiethylenetriamine (Me5dien) and L2 represents 1-aminoethylphosphonic acid (α-alaninephosphonic acid)). The obtained results suggest the formation of heteroligand complexes with [Cu(L1)(α-Ala(P))] stoichiometry in all studied systems. Additionally, in the system with en the [Cu(en)(α-Ala(P))H−1]− species is formed in basic solution. Our spectroscopic results indicate tetragonal geometry for the [Cu(en)(α-Ala(P))] species, geometry slightly …

Aqueous solutionInorganic chemistryBiophysicschemistry.chemical_elementEthylenediamineCopperBiochemistrySquare pyramidal molecular geometrylaw.inventionchemistry.chemical_compoundTrigonal bipyramidal molecular geometryCrystallographychemistrylawBasic solutionDiethylenetriaminePhysical and Theoretical ChemistryElectron paramagnetic resonanceMolecular BiologyJournal of Solution Chemistry
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Speciation of low molecular weight ligands in natural fluids: protonation constants and association of open chain polyamines with the major component…

2000

Abstract The interaction of five open chain polyamines (ethylenediamine (en), diethylenetriamine (dien), trietylenetetramine (trien), tetraethylenepentamine (tetren), spermine (sper)) with the major components of seawater was studied potentiometrically at 25°C, in an artificial seawater (containing Na+, K+, Mg2+, Ca2+, Cl− and SO42−) at different salinities (5–45‰). Potentiometric data were interpreted in terms of both the apparent protonation constants of polyamines and the formation constants of complexes formed by unprotonated or protonated amines and the cation and the anion of seawater (the inorganic content of seawater being considered as a single 1:1 salt). Some empirical relationshi…

Aqueous solutionPotentiometric titrationInorganic chemistryArtificial seawaterEthylenediamineProtonationBiochemistryAnalytical Chemistrychemistry.chemical_compoundchemistryStability constants of complexesDiethylenetriamineEnvironmental ChemistrySeawaterSpectroscopy
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CCDC 724636: Experimental Crystal Structure Determination

2010

Related Article: Fei Cheng, J.M.Dyke, F.Ferrante, A.L.Hector, W.Levason, G.Reid, M.Webster, Wenjian Zhang|2010|Dalton Trans.|39|847|doi:10.1039/b911016j

Chloro-(NNN'N''N''-pentamethyldiethylenetriamine-NN'N'')-germanium(ii) trichlorogermanate(ii)Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Binuclear Ni(II) complexes based on bridging oxalate and tetracyanometallates.

2002

The trimeric complexes, [{Ni(dien)}2(m-ox){(m-Pd(CN)4)}] (2) and [{Ni(dien)}2(m-ox){(m-Pt(CN)4)}] (3) were synthesised by the reaction of [{Ni(dien)(H2O)}2(m-ox)](PF6)2/2H2O (dien � /dietylenetriamine and ox� /oxalate) with K2Pd(CN)4 and K2Pt(CN)4, respectively. In this reaction, water substitution and molecular reconstruction reactions take place to afford trimer complexes. These compounds are isostructural with the molecular compound [{Ni(dien)}2(m-ox){(m-Ni(CN)4)}] (1). In each complex, the two octahedrally coordinated Ni atoms are oxalate bridged and the sphere of coordination of each Ni is completed by three nitrogen atoms from a diethylenetriamine ligand in fac arrangement and one nit…

DenticityChemistryLigandStereochemistrychemistry.chemical_elementTrimerCrystal structureOxalateInorganic Chemistrychemistry.chemical_compoundNickelCrystallographyDiethylenetriamineMaterials ChemistryPhysical and Theoretical ChemistryIsostructuralPolyhedron
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New Cu(II) and Zn(II) complexes of benzolamide with diethylenetriamine: synthesis, spectroscopy and X-ray structures

2000

Abstract New benzolamide (H2bz, 5-phenylsulfonamide-1,3,4-thiadiazole-2-sulfonamide) zinc(II) and copper(II) complexes with diethylenetriamine were synthesized and characterized. The crystal structures of the [M(Hbz)2(dien)] (M=Cu(II), Zn(II); dien=diethylenetriamine) complexes were determined. The metal centre adopts a near regular square pyramidal geometry. The benzolamidate anion acts as a monodentate ligand through the thiadiazole N atom contiguous to the deprotonated sulfonamido group. Spectroscopic properties are in good agreement with the crystal structures. The EPR and electronic spectroscopic studies showed that the copper(II) species doped into the zinc(II) complex adopts a near s…

DenticityInorganic chemistrychemistry.chemical_elementZincCrystal structureCopperSquare pyramidal molecular geometryInorganic ChemistryMetalCrystallographychemistry.chemical_compoundDeprotonationchemistryvisual_artDiethylenetriamineMaterials Chemistryvisual_art.visual_art_mediumPhysical and Theoretical ChemistryPolyhedron
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Binuclear Nickel(II) Complexes Based on Bridging Oxalate and Pseudohalides as Peripheral Ligands: Synthesis, Crystal Structure, DFT Calculations and …

2000

Nickel(II) molecular complexes were obtained by water displacement reactions of [{Ni(dien)(H2O)}2(μ-ox)]Cl2 and the corresponding pseudohalide. The three nickel(II) compounds [{Ni(N3)(dien)}2(μ-ox)] (1), [{Ni(NCO)(dien)}2(μ-ox)] · H2O (2) and [{Ni(NCS)(dien)}2(μ-ox)] (3) are almost isostructural. The structure determinations reveal the presence of a binuclear complex with C2h symmetry, where the oxalate ligand is coordinated in a bis(bidentate) fashion to the twofold related nickel atoms. The distorted octahedral environment of each nickel atom is completed by the three nitrogen atoms of the diethylenetriamine ligand in a fac arrangement and one nitrogen atom from a pseudohalide ligand. Mag…

DenticityLigandStereochemistrychemistry.chemical_elementCrystal structureMagnetic susceptibilityOxalateInorganic Chemistrychemistry.chemical_compoundNickelCrystallographychemistryDiethylenetriamineIsostructuralEuropean Journal of Inorganic Chemistry
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