Search results for "dilation"

Bifidobacterium pseudocatenulatum CECT 7765 supplementation restores altered vascular function in an experimental model of obese mice

2017

Aims. Bifidobacterium pseudocatenulatum CECT 7765 improves metabolic and immunological altered functions in high fat fed mice, however little is known about the effects of potential probiotics on vascular reactivity. The aim of the present study was to investigate the effects of a potential probiotic strain, Bifidobacterium pseudocatenulatum CECT 7765, on vascular response in obese mice. Methods. Aorta samples were obtained from mice, which were divided into three groups: a control group, receiving a standard diet; an obese group, receiving a high-fat diet; and an obese group receiving high-fat diet and a daily dose of B. pseudocatenulatum CECT 7765 by oral gavage. Aortic rings were suspend…

Unusual perforation after balloon dilation in a Crohn's disease patient:report of a case

2011

Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis.

2005

Objective— Sedentary lifestyle is associated with increased cardiovascular events. The underlying molecular mechanisms are incompletely understood. Reactive oxygen species (ROS) contribute to endothelial dysfunction and atherosclerosis. An important source of vascular ROS is the NADPH oxidase. Methods and Results— C57BL6 mice were subjected to regular housing (physical inactivity) or voluntary training on running wheels (6 weeks). Inactivity increased vascular lipid peroxidation to 148±9% and upregulated superoxide release to 176±17% (L-012 chemiluminescence) and 188±29% (cytochrome C reduction assay), respectively. ROS production was predominantly increased in the endothelium and the medi…

Atklāts, krustota dizaina ultra-ilgstošas darbības β2-agonista olodaterola un īsas darbības β2-agonista salbutamola bronhodilatējošas ietekmes ātruma…

2018

Astmai un hroniskai obstruktīvai plaušu slimībai (HOPS) ir liela socio-ekonomiska ietekme uz sabiedrīebu un tās ir vienas no galvenajiem saslimstības un mirstības cēloņiem pasaulē. Šo obstruktīvo plaušu slimību ārstēšana balstās uz β2-agonistu un citu zāļu bronhodilatatora iedarbību. Lai salīdzinātu ilgstošas-darbības β2-agonista olodaterola bronhodilatācijas efektu ar īslaicīgas-darbības β2-agonistu salbutamolu tika veikts atklāto pārbaužu eksperimentāls pētījums, kurā piedalījās 10 pacienti ar HOPS vai astmu, un tika noteikts abu zāļu bronhodilatācijas efekts, izmantojot FEV1 kā galveno parametru. Tika veikti ķermeņa plejismogrāfijas izmeklējumi, kuru laikā nolasīja sākumpunkta vērtību. 5…