Search results for "disabled person"

showing 10 items of 127 documents

Disease and patient characteristics in NP-C patients: findings from an international disease registry.

2013

Abstract Background Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterized by progressive neurodegeneration and premature death. We report data recorded at enrolment in an ongoing international NP-C registry initiated in September 2009 to describe disease natural history, clinical course and treatment experience of NP-C patients in clinical practice settings. Methods The NPC Registry is a prospective observational cohort study. Participating sites are encouraged to evaluate all consecutive patients with a confirmed diagnosis of NP-C, regardless of their treatment status. All patients undergo clinical assessments and medical care as determined by their physicians. D…

MalePediatricslcsh:Medicine[SDV.GEN] Life Sciences [q-bio]/Genetics0302 clinical medicineMiglustatDiagnosisGenetics(clinical)Pharmacology (medical)Prospective StudiesRegistriesAge of OnsetEnzyme InhibitorsChildProspective cohort studyGenetics (clinical)Medicine(all)0303 health sciencesCholestasisNiemann-Pick disease type CNiemann-Pick Disease Type CGeneral MedicineDysphagia3. Good healthChild PreschoolCohortNeurologicalFemalemedicine.symptomCohort studymedicine.drugHepatomegalymedicine.medical_specialty1-DeoxynojirimycinAtaxiaAdolescent03 medical and health sciencesDisease registrymedicineHumansDisabled PersonsVertical supranuclear palsy030304 developmental biology[SDV.GEN]Life Sciences [q-bio]/Geneticsbusiness.industryResearchlcsh:RInfantMutationSymptomsSplenomegalyAge of onsetbusiness030217 neurology & neurosurgery
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Risk of Persistent Disability in Patients With Pediatric-Onset Multiple Sclerosis

2021

Importance Availability of new disease-modifying therapies (DMTs) and changes of therapeutic paradigms have led to a general improvement of multiple sclerosis (MS) prognosis in adults. It is still unclear whether this improvement also involves patients with pediatric-onset MS (POMS), whose early management is more challenging. Objective To evaluate changes in the prognosis of POMS over time in association with changes in therapeutic and managing standards. Design, Setting, and Participants Retrospective, multicenter, observational study. Data were extracted and collected in May 2019 from the Italian MS Registry, a digital database including more than 59 000 patients. Inclusion criteria were…

MaleRegistriePediatricsAdolescent; Adult; Age of Onset; Aged; Child; Child Preschool; Female; Humans; Italy; Male; Middle Aged; Multiple Sclerosis; Registries; Retrospective Studies; Risk Factors; Young Adult; Disabled Persons; Disease ProgressionRisk of Disability0302 clinical medicineRisk FactorsRetrospective StudieMultiple Sclerosi030212 general & internal medicineRegistriesAge of OnsetChildOriginal InvestigationHazard ratioConfoundingMiddle Agedpediatric-onset MS (POMS)Italytherapeutic and managing standardsChild PreschoolDisease ProgressionSettore MED/26 - NeurologiaFemaleDisabled PersonHumanAdultmedicine.medical_specialtyMultiple SclerosisAdolescentMEDLINEProfile of mood states03 medical and health sciencesYoung AdultmedicineHumansIn patientDisabled PersonsPreschoolpediatric-onset MS (POMS) therapeutic and managing standardsRetrospective StudiesAgedExpanded Disability Status Scalebusiness.industryPediatric-Onset Multiple SclerosisMultiple sclerosisRisk Factormedicine.diseaseObservational studyNeurology (clinical)business030217 neurology & neurosurgery
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Geographic conditioning in dietary, social, and health patterns in elderly population with disabilities

2018

Abstract Objective The aim of this study was to identify the most relevant variables defining the dietary, social, and health patterns of elderly populations with disabilities, considering their geographic profile. Methods A cross-sectional study was carried out in a sample of 354 disabled, free-living elderly adults from three different geographic profiles (metropolitan, rural, and mixed profile). The dietary data were obtained through a validated food habit questionnaire. The data regarding health status, cohabitation unit, and social benefits were obtained through the public social services. A standardized principal component analysis was used to select the most relevant variables, by co…

MaleRural Population0301 basic medicineCalorieUrban PopulationHealth StatusEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismSample (statistics)Social WelfareUnit (housing)03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesEnvironmental healthHumansDisabled PersonsGeriatric AssessmentAgedAged 80 and overConsumption (economics)030109 nutrition & dieteticsNutrition and DieteticsFeeding BehaviorMetropolitan areaDietCross-Sectional StudiesCohabitationSocioeconomic FactorsFemaleRural areaEnergy IntakePsychologyNutrition
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Disability-related-distress in primary school learners with vision impairment due to uncorrected refractive error in KwaZulu-Natal Province, South Af…

2020

Background Uncorrected refractive error (URE) is a major cause of vision impairment among children that impacts negatively on their lives including distresses. We aim to understand the disability-related distress among vision-impaired children due to URE in rural and semi-rural South Africa using qualitative techniques. Methods Structured focus groups of children (aged 5-12 years old) with normal vision and vision impairment due to URE from four schools in Pinetown, KwaZulu Natal, South Africa, were performed (four mixed-gender group discussions and eight single gender group discussions). We recruited the study participants after the children underwent standardised vision screening. Criteri…

MaleRural PopulationRefractive errorCross-sectional studyVisionSocial SciencesPsychological DistressFamiliesSouth Africa0302 clinical medicineSociologyMedicine and Health SciencesPsychologyPublic and Occupational Health030212 general & internal medicineChildChildrenmedia_commonVisual ImpairmentsMultidisciplinarySchoolsQHumiliationRRefractive ErrorsSports ScienceDistressProfessionsSelf-confidenceChild PreschoolMedicineSensory PerceptionFemaleAnatomyPsychologyKwazulu natalClinical psychologyResearch ArticleSportsmedia_common.quotation_subjectScienceDisabilitiesVision DisordersEducation03 medical and health sciencesOcular SystemmedicineHumansDisabled PersonsStudentsBehaviorBiology and Life SciencesTeachersmedicine.diseaseFocus groupOphthalmologyCross-Sectional StudiesAge GroupsPeople and Places030221 ophthalmology & optometryEyesRecreationPopulation GroupingsHeadStress PsychologicalQualitative researchNeurosciencePLoS ONE
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Intra-Rater Test-Retest Reliability of a Modified Child Functioning Module, Self-Report Version

2020

Determining disability prevalence is a growing area for population statistics, especially among young adolescents. The Washington Group on Disability Statistics is one source of reporting disabilities through functional difficulties. Yet, young adolescents self-reporting through this measure is in its infancy. The purpose of this study was to carry out an intra-rater test-retest reliability study on a modified set of items for self-reporting functional difficulties. Young adolescents (N = 74

MaleWashingtonAdolescenttoimintahäiriötintraclass correlation coefficientlcsh:Medicinelapset (ikäryhmät)WalkingArticleDisability Evaluationhealth behaviorerityisopetusSurveys and QuestionnairesPrevalenceHumansDisabled Personssurveyfunctional difficultiesChildkappayoung adolescentsFinlandspecial educationObserver Variationlcsh:RReproducibility of ResultsterveyskäyttäytyminenFemaleSelf Reportdisability statistics
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Active aging – resilience and external support as modifiers of the disablement outcome: AGNES cohort study protocol

2018

Background: Population aging increases the need for knowledge on positive aspects of aging, and contributions of older people to their own wellbeing and that of others. We defined active aging as an individual’s striving for elements of wellbeing with activities as per their goals, abilities and opportunities. This study examines associations of health, health behaviors, health literacy and functional abilities, environmental and social support with active aging and wellbeing. We will develop and validate assessment methods for physical activity and physical resilience suitable for research on older people, and examine their associations with active aging and wellbeing. We will examine coho…

MaleaktiivisuusAgingympäristöhyvinvointiHealth BehaviorEnvironmentfunctioningCohort StudiesStudy ProtocolwellbeingvammaisuustoimintakykyHumansDisabled PersonsFunctioningExerciseFinlandAgedAged 80 and overMobilityLower extremityDisabilityexerciseWellbeinglcsh:Public aspects of medicineagingCohortSocial Supportlcsh:RA1-1270cohortResilience PsychologicalHealth LiteracyActivityikääntyminenliikkuvuuslower extremityFemalefyysinen aktiivisuusBMC Public Health
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Global and regional burden of disease and injury in 2016 arising from occupational exposures: a systematic analysis for the Global Burden of Disease …

2020

ObjectivesThis study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study.MethodsThe GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors.ResultsIn 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39…

Maleexposure assessmentGlobal Healthmedicine.disease_causeGlobal Burden of DiseaseergonomicGBD 2016 Occupational Risk Factors Collaborators0302 clinical medicineRisk Factors1599 Other Commerce Management Tourism and ServicesNeoplasmsMETABOLIC RISKSPer capitaMedicine1506030212 general & internal medicinePublic Environmental & Occupational HealthAged 80 and overeducation.field_of_studyHuman factors and ergonomicsMiddle Aged030210 environmental & occupational health3142 Public health care science environmental and occupational health3. Good healthOccupational DiseasesCOMPARATIVE RISK-ASSESSMENTFemaleQuality-Adjusted Life YearsRisk assessmentLife Sciences & BiomedicineAdultCOUNTRIESnoiseAdolescentPopulationcancer; ergonomic; noise; respiratory tract diseases; workplaceRisk AssessmentEnvironmental & Occupational HealthAsbestosrespiratory tract disease1117 Public Health and Health ServicesYoung Adult03 medical and health sciencesAge DistributionLife ExpectancyOccupational ExposureEnvironmental healthHumanscancerDisabled PersonsSex DistributioneducationAgedScience & Technologybusiness.industryPublic Health Environmental and Occupational Health1103 Clinical SciencesTRENDSQuality-adjusted life yearrespiratory tract diseasesworkplaceSocioeconomic FactorsAttributable riskCommentaryLife expectancyWounds and InjuriesCLUSTERSbusinessLow Back PainOccupational and Environmental Medicine
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Quality of life and disability:can they be improved by active postoperative rehabilitation after spinal fusion surgery in patients with spondylolisth…

2017

Purpose The aim of the study was to investigate the effectiveness of the postoperative 12-month exercise program compared to usual care on disability and health-related quality of life (HRQoL) in patients after lumbar spine fusion surgery (LSF). Methods Altogether, 98 patients with isthmic (31) or degenerative (67) spondylolisthesis were randomised to exercise therapy group (EG) (n = 48) or usual care group (UCG) (n = 50) 3 months after LSF. EG patients had home-based progressive strength and aerobic training program for 12 months. UCG patients received only oral and written instructions of exercises. Oswestry Disability Index (ODI) and HRQoL (RAND-36) were evaluated at the time of randomiz…

Malefusionmedicine.medical_specialtyRandomizationfysioterapialaw.inventionspine surgery03 medical and health sciencesvammaisuus0302 clinical medicineQuality of lifeRandomized controlled triallawmedicineAerobic exerciseHumansOrthopedics and Sports MedicineIn patientDisabled Persons030212 general & internal medicineAgedbusiness.industrylumbar spineMiddle Agedmedicine.diseaseSpondylolisthesisOswestry Disability IndexExercise Therapyhealth-related quality of lifeSpinal FusionPhysical therapyQuality of LifeSurgeryFemaleNeurosurgerySpondylolisthesisbusiness030217 neurology & neurosurgeryFollow-Up Studies
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Retirement as a predictor of physical functioning trajectories among older businessmen

2022

Abstract Background Associations between retirement characteristics and consequent physical functioning (PF) are poorly understood, particularly in higher socioeconomic groups, where postponing retirement has had both positive and negative implications for PF. Methods Multiple assessments of PF, the first of which at the mean age of 73.3 years, were performed on 1709 men who were retired business executives and managers, using the RAND-36/SF-36 instrument, between 2000 and 2010. Questionnaire data on retirement age and type of pension was gathered in 2000. Five distinct PF trajectories were created using latent growth mixture modelling. Mortality- and covariate-adjusted multinomial regressi…

Malefyysinen toimintakykyage at retirementtype of pensionPensionsAGESurveys and Questionnairesphysical functioningHumansDisabled PersonsAgedWORKRetirementyrittäjätMORTALITYDISABILITYAge at retirementASSOCIATIONADULTSLOWER-EXTREMITY FUNCTIONDISEASES3121 General medicine internal medicine and other clinical medicineeläkkeelle siirtymineneläkeikämiehetLIFE-STYLEGeriatrics and Gerontologyhuman activitiesPhysical functioningikääntyneetType of pensionMIDLIFE
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The physical activity patterns of adolescents with intellectual disabilities: A descriptive study

2014

Abstract Background Emerging data suggest that adolescents with intellectual disabilities (IDs) have lower physical activity (PA) levels and have a higher incidence of obesity than their peers without IDs. Objective To examine daily PA patterns (weekdays vs. weekend days) of adolescents with IDs among boys and girls. The contributions of PA at school, including school recesses and physical education time, and PA outside of school were also analyzed. Methods Participants included forty-nine adolescents with mild to moderate IDs (mean 15.3 years) from the Valencia region (Spain). Adolescents wore a pedometer for seven consecutive days to measure PA objectively and filled in a daily activity l…

Malemedicine.medical_specialtyAdolescentHealth BehavioreducationOverweightSpecial educationBody Mass Index03 medical and health sciences0302 clinical medicineIntellectual DisabilityIntellectual disabilitymedicineHumansDisabled PersonsObesity030212 general & internal medicineExerciseSchoolsIncidence (epidemiology)Public Health Environmental and Occupational HealthActigraphy030229 sport sciencesGeneral Medicinemedicine.diseaseActigraphyObesitySpainPedometerPhysical therapyFemalemedicine.symptomPsychologyBody mass indexDemographyDisability and Health Journal
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