Search results for "displacements"

showing 5 items of 15 documents

Neutron Scattering Reveals Enhanced Protein Dynamics in Concanavalin A Amyloid Fibrils

2012

Protein aggregation is one of the most challenging topics in life sciences, and it is implicated in several human pathologies. The nature and the role of toxic species is highly debated, with amyloid fibrils being among the most relevant species for their peculiar structural and functional properties. Protein dynamics and in particular the ability to fluctuate through a large number of conformational substates are closely related to protein function. This Letter focuses on amyloid fibril dynamics, and, to our knowledge, it is the first neutron scattering study on a protein (Concanavalin A) isolated in its fibril state. Our results reveal enhanced atomic fluctuations in amyloid fibrils and i…

Protein functionbiologyChemistryProtein dynamicsmean square displacementsA proteinatomic fluctuationsmacromolecular substancesProtein aggregationNeutron scatteringFibrilAmyloid fibrilatomic fluctuationprotein aggregationCrystallographyConcanavalin ABiophysicsbiology.proteinGeneral Materials SciencePhysical and Theoretical Chemistry
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Toward a Comprehensive Dam Monitoring: On-Site and Remote-Retrieved Forcing Factors and Resulting Displacements (GNSS and PS–InSAR)

2021

Many factors can influence the displacements of a dam, including water level variability and environmental temperatures, in addition to the dam composition. In this work, optical-based classification, thermal diachronic analysis, and a quasi-PS (Persistent Scatter) Interferometric SAR technique have been applied to determine both forcing factors and resulting displacements of the crest of the Castello dam (South Italy) over a one-year time period. The dataset includes Sentinel-1A images acquired in Interferometric Wide swath mode using the Terrain Observation with Progressive Scans SAR (TOPSAR); Landsat 8 Thermal Infrared Sensor (TIRS) thermal images, and Global Navigation Satellite System …

010504 meteorology & atmospheric sciencesLandsat TIRSScience0211 other engineering and technologiesTerrainSatellite system02 engineering and technologyForcing (mathematics)01 natural sciencesPS–InSARInterferometric synthetic aperture radarDam displacements Full graph GNSS Landsat TIRS PS–InSAR Sentinel-1A TOPSARSentinel-1A TOPSAR021101 geological & geomatics engineering0105 earth and related environmental sciencesRemote sensingdam displacementsGNSSQfull graphdam displacements; GNSS; Sentinel-1A TOPSAR; Landsat TIRS; PS–InSAR; full graphWater levelInterferometryGNSS applicationsGeneral Earth and Planetary SciencesSatelliteGeologySettore ICAR/06 - Topografia E CartografiaRemote Sensing
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Molecular origin and hydration dependence of protein anharmonicity: an elastic neutron scattering study.

2010

Two main onsets of anharmonicity are present in protein dynamics. Neutron scattering on protein hydrated powders revealed a first onset at about 150 K and a second one at about 230 K (the so called dynamical transition). In order to assess the molecular origin of protein anharmonicity, we study different homomeric polypeptides by incoherent elastic neutron scattering, thus disentangling the contribution of different molecular groups in proteins. We show that methyl group rotations are the main contributors to the low temperature onset. Concerning the dynamical transition, we show that it also occurs in absence of side chains; however, the presence and mobility of side chains substantially i…

Elastic scatteringQuantitative Biology::BiomoleculespolypeptideTransition temperatureProtein dynamicsAnharmonicitymean square displacementsTemperatureGeneral Physics and AstronomyProteinsWaterNeutron scatteringElasticitychemistry.chemical_compoundCrystallographyNeutron DiffractionAmplitudechemistryChemical physicsprotein dynamicSide chainPhysics::Chemical PhysicsPhysical and Theoretical ChemistryPeptidesMethyl groupPhysical chemistry chemical physics : PCCP
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Dynamical properties of myoglobin in an ultraviscous water-glycerol solvent investigated with elastic neutron scattering and FTIR spectroscopy

2018

Abstract Proteins have distinctive dynamical properties, characterized by the fluctuations of protein molecules among the different minima of their energy landscape. These fluctuations, progressively activated for temperature values larger than ~180 K, lead to a steep increase in the temperature dependence of all measurable dynamical properties. This phenomenon is known as Protein Dynamical Transition and, in spite of the intense studies due to its importance in protein function and to the relation with the fascinating fundamental thermodynamics of complex systems, many aspects of it are not yet clearly understood. Among these, the relationship with the properties of the external solvent an…

Materials Chemistry2506 Metals and AlloysMaterials scienceAtomic and Molecular Physics and OpticHydrogenchemistry.chemical_element02 engineering and technologyNeutron scatteringCondensed Matter PhysicNeutron scattering010402 general chemistry01 natural sciencesQuantitative Biology::Subcellular Processeschemistry.chemical_compoundAmide bands; Fourier transform infrared spectroscopy; Mean square displacements; Neutron scattering; Protein dynamical transition; Electronic Optical and Magnetic Materials; Atomic and Molecular Physics and Optics; Condensed Matter Physics; Spectroscopy; Physical and Theoretical Chemistry; Materials Chemistry2506 Metals and AlloysMaterials ChemistrySide chainMoleculeAmide bandFourier transform infrared spectroscopyPhysical and Theoretical ChemistrySpectroscopySpectroscopyMean square displacementQuantitative Biology::BiomoleculesAmide bandsElectronic Optical and Magnetic MaterialProtein dynamical transitionEnergy landscapeFourier transform infrared spectroscopy021001 nanoscience & nanotechnologyCondensed Matter PhysicsMean Square DisplacementsAtomic and Molecular Physics and OpticsSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)0104 chemical sciencesElectronic Optical and Magnetic MaterialsMyoglobinchemistryFTIRChemical physics0210 nano-technology
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Reservoir monitoring using satellite SAR and GNSS: a case study in southern Italy

2018

Recently, it has been demonstrated that it is possible to relate water levels of a reservoir with its dam displacements. Water levels were determined via remote sensing, while dam displacements were measured via Global Navigation Satellite System (GNSS). Results have shown that displacements and water levels are correlated.Water levels at the Magazzolo reservoir in southern Italy were firstly retrieved using two remote sensing approaches: by visual matching between the reservoir shoreline and contour lines, and by evaluating the surface extent via unsupervised classification to estimate the water levels with an area/depth relation. Dam displacements were measured using GPS receivers on the …

Reservoir monitoringGNSS applicationsSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaEnvironmental scienceSatellitedam displacements GNSS Interferometry remote sensing SAR water levelSettore ICAR/06 - Topografia E CartografiaRemote sensing
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