Search results for "dissemination"

showing 10 items of 106 documents

Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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Distributed Resource Allocation in Underlay Multicast D2D Communications

2021

Multicast device-to-device communications operating underlay with cellular networks is a spectral efficient technique for disseminating data to nearby receivers. However, due to the critical challenge of having an intelligent interference coordination between multicast groups along with the cellular network, it is necessary to judiciously perform resource allocation for the combined network. In this work, we present a framework for a joint channel and power allocation strategy to maximize the sum rate of the combined network while guaranteeing minimum rate to individual groups and cellular users. The objective function is augmented by an austerity function that penalizes excessive assignmen…

Mathematical optimizationMulticastChannel allocation schemesComputer science020206 networking & telecommunications020302 automobile design & engineeringThroughput02 engineering and technology0203 mechanical engineeringDistributed algorithm0202 electrical engineering electronic engineering information engineeringCellular networkResource allocationElectrical and Electronic EngineeringUnderlayDisseminationCommunication channelIEEE Transactions on Communications
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Reliable Multicast D2D Communication Over Multiple Channels in Underlay Cellular Networks

2020

Multicast device-to-device (D2D) communications operating underlay with cellular networks is a spectral efficient technique for disseminating data to the nearby receivers. However, due to critical challenges such as, mitigating mutual interference and unavailability of perfect channel state information (CSI), the resource allocation to multicast groups needs significant attention. In this work, we present a framework for joint channel assignment and power allocation strategy to maximize the sum rate of the combined network. The proposed framework allows access of multiple channels to the multicast groups, thus improving the achievable rate of the individual groups. Furthermore, fairness in …

Mathematical optimizationMulticastComputer scienceChannel state informationReliable multicastCellular networkResource allocationThroughputUnderlayDisseminationComputer Science::Information TheoryCommunication channel2020 IEEE 31st Annual International Symposium on Personal, Indoor and Mobile Radio Communications
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Sengenyadance of theDigocommunity: Documentation of social context, music transcriptions and acoustic measurements of selected instruments

2015

ABSTRACTThis paper documents social and cultural aspects of Sengenya music which is practiced by Digo community (from the coast region in Kenya). Specifically the paper addresses (a) Background and Regional (Country) Context, (b) Social Context and Description of Sengenya Music, (c) Melodic transcriptions of Chivoti melodies, rhythmic transcriptions of the Six Drum Rhythms, and (d) Acoustic Measurement of selected chivoti Instruments and pitch registers of the drums used to accompany the dance. While there has been some documentation (Zake 1986, Darkwa 1991, Nyakiti 2007) of general social /cultural aspects of the Digo people (including other Coastal communities), scanty information exists …

MelodyKenyaHistoryDanceanalysisInformation DisseminationContext (language use)music transcriptioncultural dancecomputer.software_genredocumentation050105 experimental psychology060404 musicDigo communityDocumentationTranscription (linguistics)0501 psychology and cognitive sciencesMultimedia05 social sciencesSocial environment06 humanities and the artsLinguisticsta6131acoustic measurementscomputer0604 artsMusicMuziki
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The role of public biological resource centers in providing a basic infrastructure for microbial research

2009

Public collections of microorganisms have been established since the late 19th century, and currently 573 service collections are registered at the World Data Center for Microorganisms (www.wdcm.org). All together, they hold more than 1.5 million microorganisms. By implementing guidelines compiled by the Organisation for Economic Co-operation and Development (OECD), many public service collections evolve into professional ex situ repositories of biodiversity and distribution nodes for known, validated and precisely identified microbial resources and associated information to legitimate end-users. These Biological Resource Centers (BRCs) may be the preferred mechanism for the appropriate exp…

Microbiological TechniquesQuality ControlConvention on Biological DiversityBiomedical ResearchResource (biology)Information Disseminationbusiness.industrymedia_common.quotation_subjectEnvironmental resource managementInteroperabilityInformation DisseminationInternational AgenciesBiodiversityGeneral MedicineBiologyMicrobiologyTransparency (behavior)Technology TransferService (economics)Public servicebusinessCommonsMolecular BiologyBiological Specimen Banksmedia_commonResearch in Microbiology
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On Constructing Persistent Identifiers with Persistent Resolution Targets

2016

Persistent Identifiers (PID) are the foundation referencing digital assets in scientific publications, books, and digital repositories. In its realization, PIDs contain metadata and resolving targets in form of URLs that point to data sets located on the network. In contrast to PIDs, the target URLs are typically changing over time; thus, PIDs need continuous maintenance -- an effort that is increasing tremendously with the advancement of e-Science and the advent of the Internet-of-Things (IoT). Nowadays, billions of sensors and data sets are subject of PID assignment. This paper presents a new approach of embedding location independent targets into PIDs that allows the creation of maintena…

Networking and Internet Architecture (cs.NI)FOS: Computer and information scienceslcsh:T58.5-58.64lcsh:Information technologyComputer sciencebusiness.industryOverlay network020206 networking & telecommunications02 engineering and technologycomputer.file_formatMaintenance engineeringlcsh:QA75.5-76.95IdentifierMetadataComputer Science - Networking and Internet ArchitectureData accessEncoding (memory)0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processinglcsh:Electronic computers. Computer sciencebusinessDisseminationBitTorrentcomputerComputer network
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Effectiveness of Safety Warnings in Atypical Antipsychotic Drugs

2009

Studies conducted to obtain drug authorization are often of short duration and based on small sample sizes in selected populations. Policies on drug safety rely on the validity of the methods used to achieve rapid and effective communication of new information. No formal evaluation has ever been made of the Spanish communications system, although indirect data have raised questions about its effectiveness.To evaluate the impact of two safety warnings issued by the Spanish Drug Agency, and of a later prior authorization requirement involving the use of atypical antipsychotic drugs in the elderly.The study was based on a time-series analysis constructed with data corresponding to monthly invo…

Olanzapinemedicine.medical_specialtymedicine.drug_classAtypical antipsychoticToxicologyCommunications systemInterrupted Time Series AnalysisBenzodiazepinesmedicineHumansPharmacology (medical)ZiprasidoneAmisulpridePractice Patterns Physicians'Medical prescriptionPsychiatryAgedPharmacologyRisperidoneDose-Response Relationship DrugInformation Disseminationbusiness.industryRisperidonemedicine.diseaseOlanzapineSpainDrug and Narcotic ControlDementiaMedical emergencybusinessAntipsychotic Agentsmedicine.drugDrug Safety
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Tweet this: how advocacy for breast and prostate cancers stacks up on social media.

2017

OncologyMalemedicine.medical_specialty020205 medical informaticsDatabases FactualUrologyMEDLINEBreast Neoplasms02 engineering and technology03 medical and health sciences0302 clinical medicineProstateInternal medicine0202 electrical engineering electronic engineering information engineeringmedicineHumansSocial media030212 general & internal medicineRetrospective Studiesbusiness.industryInformation DisseminationIncidence (epidemiology)IncidenceProstatic NeoplasmsRetrospective cohort studyUnited Kingdommedicine.anatomical_structureFamily medicineFemalebusinessSocial MediaBJU international
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High Lymph Vessel Density and Expression of Lymphatic Growth Factors in Peritoneal Endometriosis

2012

To investigate the occurrence of lymph vessels and lymphangiogenic growth factors in peritoneal lesions, we performed immunohistochemical staining of peritoneal lesions of 37 patients with antibodies against podoplanin (D2-40), lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1), prospero homeobox protein 1 (Prox-1), vascular epithelial growth factor (VEGF)-C/VEGF-D. Overall, 10 lesions were double stained against D2-40 and von Willebrand factor. The lymph vessel density in peritoneal lesion was significantly higher in comparison with healthy peritoneum. All lymph vessel makers could be detected, whereby the lymph vessel density of LYVE-1- and Prox-1-positive lymph vessels was signi…

Pathologychronic inflammatory proceMacrophageVascular Endothelial Growth Factor CVascular Endothelial Growth Factor DVesicular Transport ProteinsFluorescent Antibody TechniquePeritoneal DiseasesAntibodies Monoclonal Murine-Derivedlymphatic disseminationIntercellular Signaling Peptides and ProteinEndometriosiEndothelial CellObstetrics and GynecologyHomeodomain ProteinMiddle AgedImmunohistochemistryLymphangiogenesisLymphatic systemmedicine.anatomical_structureVascular endothelial growth factor CIntercellular Signaling Peptides and ProteinsFemaleLymphEndothelium LymphaticHumanAdultmedicine.medical_specialtyEndometriosisendometriosis; lymphatic dissemination; chronic inflammatory processlymphangiogenesiperitoneal endometriosiLymphatic VesselVesicular Transport ProteinPeritoneummedicineLymphatic vesselLymph node stromal cellHumansLymph sacsLymphatic VesselsHomeodomain ProteinsTumor Suppressor Proteinbusiness.industryMacrophagesTumor Suppressor ProteinsEndothelial CellsBiomarkerchronic inflammatory processPeritoneal DiseasebusinessBiomarkersReproductive Sciences
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PRINTO/PRES international website for families of children with rheumatic diseases: www.pediatric-rheumatology.printo.it

2005

To prepare a website for families and health professionals containing up to date information about paediatric rheumatic diseases (PRD).Firstly, paediatric rheumatology centres and family self help associations were surveyed to characterise current clinical practice of physicians providing care for children with PRD, research activities, and training facilities of each centre. Secondly, international consensus was reached on the content of the website. Finally, the website was developed and the texts translated.The web page contains three main sections: (a) description for families of the characteristics of 15 PRD; (b) list of paediatric rheumatology centres; (c) contact information for fami…

Pediatricsmedicine.medical_specialtyInternational CooperationImmunologyInformation DisseminationAlternative medicinePediatricsGeneral Biochemistry Genetics and Molecular BiologySelf-helpPatient Education as TopicRheumatologyRheumatic DiseasesmedicineImmunology and AllergyHumansPediatric rheumatologyChildInternetbusiness.industryInformation DisseminationClinical trialClinical PracticeFamily medicineOccasional PieceEducation Medical ContinuingbusinessPaediatric rheumatologyPatient education
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