Search results for "distress"
showing 10 items of 555 documents
Initiation of high-frequency oscillatory ventilation and its effects upon cerebral circulation in pigs: an experimental study
2006
BACKGROUND: Current practice at high-frequency oscillatory ventilation (HFOV) initiation is a stepwise increase of the constant applied airway pressure to achieve lung recruitment. We hypothesized that HFOV would lead to more adverse cerebral haemodynamics than does pressure controlled ventilation (PCV) in the presence of experimental intracranial hypertension (IH) and acute lung injury (ALI) in pigs with similar mean airway pressure settings. METHODS: In 12 anesthetized pigs (24-27 kg) with IH and ALI, mean airway pressure (P(mean)) was increased (to 20, 25, 30 cm H(2)O every 30 min), either with HFOV or with PCV. The order of the two ventilatory modes (cross-over) was randomized. Mean art…
Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies …
2023
Background: There is insufficient evidence to guide ventilatory targets in acute brain injury (ABI). Recent studies have shown associations between mechanical power (MP) and mortality in critical care populations. We aimed to describe MP in ventilated patients with ABI, and evaluate associations between MP and clinical outcomes. Methods: In this preplanned, secondary analysis of a prospective, multi-center, observational cohort study (ENIO, NCT03400904), we included adult patients with ABI (Glasgow Coma Scale ≤ 12 before intubation) who required mechanical ventilation (MV) ≥ 24 h. Using multivariable log binomial regressions, we separately assessed associations between MP on hospital day (H…
Polyvictimization and Cybervictimization Among College Students From France: The Mediation Role of Psychological Distress and Resilience
2019
Few studies have explored potential associations between polyvictimization and cybervictimization and even fewer have involved in college-age sample. As it has been shown in the literature, polyvictimization is associated with higher psychological distress and lower resilience. This study is aimed to model the association between polyvictimization and cybervictimization by testing the mediating role of psychological distress and resilience. The sample included 4,626 undergraduates from France. Participants completed questionnaires assessing cybervictimization, polyvictimization (emotional abuse from parents, exposure to interparental violence, parental neglect, unwanted sexual touching, an…
Los efectos a largo plazo de las competencias emocionales y la autoestima sobre los síntomas internalizantes de los adolescentes
2021
Internalizing symptoms such as depressive mood, somatic complaints and anxiety among adolescents are a major and global concern for parents, educators and professionals. Empirical research suggests that high level of self-esteem during adolescents is associated with psychological adjustment and emotional well-being. This study examines self-esteem as a potential mediator in the interplay between emotional competencies and internalizing symptoms during adolescence. Self-report data from 855 Spanish adolescents (Mage = 13.6, SD = 1.09, 52% girls) were collected in two waves, using a longitudinal design. The mediation model was estimated using structural equation modelling (SEM). Results show …
Relationship Between Mental Health and the Education Level in Elderly People: Mediation of Leisure Attitude.
2020
Purpose The present study intends to explore the influence of education on the mental health of retired people and the mediating role of a leisure attitude in this relationship. Design/methodology The sample was simple random, and a confidentiality agreement was established. The sample was composed of 403 Portuguese participants (37.2% male; 62.8% female). The participants completed the MHI and the LAS. Findings The hypothesized mediation model showed that a leisure attitude mediated the association between education and well-being. In addition, higher levels of distress were found in participants with higher levels of education. Scientific contribution Our results suggest that old-aged peo…
Evaluation of main functional dyspepsia symptoms after probiotic administration in patients receiving conventional pharmacological therapies
2021
Objective Postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) are the two main forms of functional dyspepsia (FD). Probiotics are a promising therapy for FD, but current data remains heterogeneous. This work aims to evaluate a probiotic combination of Lacticaseibacillus rhamnosus LR04 (DSM 16605), Lactiplantibacillus pentosus LPS01 (DSM 21980), Lactiplantibacillus plantarum LP01 (LMG P-21021), and Lactobacillus delbrueckii subsp. delbruekii LDD01 (DMS 22106), alone or together with other pharmacological therapies, for clinical improvement of symptoms associated with FD. Methods Patients with FD were enrolled and divided into two groups: PDS and EPS. Probiotic alone or co…
Specific Features of the Coagulopathy Signature in Severe COVID-19 Pneumonia
2021
Rationale: COVID-19 displays distinct characteristics that suggest a unique pathogenesis. The objective of this study was to compare biomarkers of coagulopathy and outcomes in COVID-19 and non-COVID-19 patients with severe pneumonia.Methods: Thirty-six non-COVID-19 and 27 COVID-19 non-immunocompromised patients with severe pneumonia were prospectively enrolled, most requiring intensive care. Clinical and biological characteristics (including plasma biomarkers of coagulopathy) were compared.Results: At similar baseline severity, COVID-19 patients required mechanical ventilation (MV) for significantly longer than non-COVID-19 patients (p = 0.0049) and more frequently developed venous thrombot…
Scrub typhus, acute respiratory distress, and hemophagocytic lymphohistiocytosis
2013
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Measles and Secondary Hemophagocytic Lymphohistiocytosis
2012
To the Editor: We found interesting the article by Lupo et al. about a case of fatal measles in an immunocompetent 29-year-old woman (Fatal measles without rash in immunocompetent adult, France; http://dx.doi.org/10.3201/eid1803.111300). Perhaps, however, the possible diagnosis of secondary hemophagocytic lymphohistiocytosis (HLH) should also have been considered in that setting. HLH is a potentially fatal hyperinflammatory syndrome characterized by histiocyte proliferation and hemophagocytosis. HLH may be inherited (i.e., primary, familial, generally occurring in infants) or may occur at any age secondary to infection, malignancy, or rheumatologic disease. Secondary HLH is determined accor…
More than Pneumonia: Distinctive Features of SARS-Cov-2 Infection. From Autopsy Findings to Clinical Implications: A Systematic Review
2020
Despite safety recommendations for the management of corpses with COVID-19 infection and the high number of deaths worldwide, the post-mortem investigation rate is extremely low as well as the scientific contributions describing the pathological features. The first results of post-mortem investigations provided interesting findings and contributed to promoting unexplored therapeutic approaches and new frontiers of research. A systematic review is provided with the aim of summarizing all autopsy studies up to February 2020 in which a complete post-mortem investigation in patients with COVID-19 disease was performed, focusing on histopathological features. We included case reports, case serie…