Search results for "diverse"

showing 10 items of 39 documents

Some European green roof norms and guidelines through the lens of biodiversity : do ecoregions and plant traits also matter?

2018

Abstract Green infrastructure and in particular green roofs are crucial to meet the challenge of sustainable urbanisation fostered by the current European Research and Innovation agenda. Several documents were issued in the last decades in Europe for regulating the design, construction and up-keep of roof greening. In particular, the actual German guidelines have been widely adopted as a reference basis for green roof design and regulation worldwide, because of its exhaustiveness and proven building- and landscaping tradition. With the aim to assess the effectiveness of green roof guidelines and norms in supporting plant and soil biodiversity in different ecoregions, and particularly of the…

Environmental Engineering010504 meteorology & atmospheric sciencesSoil biodiversitySettore AGR/13 - Chimica AgrariaGreen roofBiodiversity010501 environmental sciencesManagement Monitoring Policy and Law01 natural sciencesGermanEcoregion577: Ökologie0105 earth and related environmental sciencesNature and Landscape ConservationSettore ICAR/15 - Architettura Del PaesaggioBiodiverse green roofs Ecological design Biogeographic regions Nature-based solutions Policiesbusiness.industryEnvironmental resource managementlanguage.human_languageGeographySettore BIO/03 - Botanica Ambientale E ApplicatalanguageLandscapingNorm (social)Green infrastructurebusiness
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Hepatitis B virus maturation is sensitive to functional inhibition of ESCRT-III, Vps4, and gamma 2-adaptin.

2007

ABSTRACT Hepatitis B virus (HBV) is an enveloped DNA virus that presumably buds at intracellular membranes of infected cells. HBV budding involves two endocytic host proteins, the ubiquitin-interacting adaptor γ2-adaptin and the Nedd4 ubiquitin ligase. Here, we demonstrate that HBV release also requires the cellular machinery that generates internal vesicles of multivesicular bodies (MVBs). In order to perturb the MVB machinery in HBV-replicating liver cells, we used ectopic expression of dominant-negative mutants of different MVB components, like the ESCRT-III complex-forming CHMP proteins and the Vps4 ATPases. Upon coexpression of mutated CHMP3, CHMP4B, or CHMP4C forms, as well as of ATPa…

Hepatitis B virusVacuolar Proton-Translocating ATPasesEndosomeImmunologyEndocytic cycleVesicular Transport Proteinsmacromolecular substancesEndosomesmedicine.disease_causeMicrobiologyESCRTVirusCell LineViral ProteinsVirologymedicineHumansAdaptor Protein Complex gamma SubunitsHepatitis B virusAdenosine TriphosphatasesMicroscopy ConfocalbiologyEndosomal Sorting Complexes Required for TransportVirus AssemblyDNA virusMolecular biologyUbiquitin ligaseCell biologyGenome Replication and Regulation of Viral Gene ExpressionMicroscopy FluorescenceInsect Sciencebiology.proteinHepatocytesATPases Associated with Diverse Cellular ActivitiesEctopic expressionJournal of virology
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Principe de précaution et assistance médicale à la procréation : l'ICSI

2004

International audience

LimiteProcréation médicalement assistée[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/LawProtection maternelle et infantileSANTE PUBLIQUEComputingMilieux_MISCELLANEOUSTechniques diverses
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FinnTwin12 Cohort: An Updated Review

2019

AbstractThis review offers an update on research conducted with FinnTwin12 (FT12), the youngest of the three Finnish Twin Cohorts. FT12 was designed as a two-stage study. In the first stage, we conducted multiwave questionnaire research enrolling all eligible twins born in Finland during 1983–1987 along with their biological parents. In stage 2, we intensively studied a subset of these twins with in-school assessments at age 12 and semistructured poly-diagnostic interviews at age 14. At baseline, parents of intensively studied twins were administered the adult version of the interview. Laboratory studies with repeat interviews, neuropsychological tests, and collection of DNA were made of in…

MaleGerontologyTwinsphysical activity030508 substance abuseruokavaliotLongitudinal twin-family studydiverse phenotypes0302 clinical medicinemielenterveysEarly adulthoodgeneticsChildkohorttitutkimusFinlandGenetics (clinical)alcoholNeuropsychologyObstetrics and GynecologytwinsmetabolomicsepigenetiikkaCohorttwo-stage designFemalealkoholinkäyttö0305 other medical sciencePsychologyfyysinen aktiivisuusmental healthAdultAdolescentSubstance-Related Disorderslongitudinal twin-family studyPhysical activitypitkittäistutkimusArticlesmoking03 medical and health sciencestupakointiHumanskaksostutkimusperinnöllisyystiedeepigeneticsMental healthPediatrics Perinatology and Child HealthfenotyyppiGene-Environment InteractionSubstance usedietterveysriskit030217 neurology & neurosurgeryFollow-Up StudiesTwin Research and Human Genetics
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Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain

2009

Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…

Malemedicine.medical_specialtyTime FactorsCentral nervous systemHippocampusCell CountSettore BIO/11 - Biologia MolecolareBiologySettore BIO/09 - Fisiologiachemistry.chemical_compoundSeizuresInternal medicineSettore BIO/10 - BiochimicaCaSRmedicineAnimalsRNA MessengerRats WistarIbotenic AcidMolecular BiologyIn Situ HybridizationNeuronsKainic AcidGeneral NeuroscienceDentate gyrusBrainColocalizationImmunohistochemistryRatsOligodendrogliamedicine.anatomical_structureEndocrinologynervous systemchemistryBrain InjuriesNeurogliaNeurology (clinical)Pyramidal cellCaSR; BrainCalcium sensing receptor (CaSR) isolated for the first time from bovine and human parathyroid is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expression in neurons and oligodendrocytes whereas it was not found expressed both in the microglia and in astrocytes. One week after kainate-induced seizure CaSR was found in the injured CA3 region of the hippocampus and very interestingly it was found up-regulated in the neurons of CA1-CA2 and dentate gyrus. Similarly 1 week following ibotenic acid injection in the hippocampus CaSR mRNA expression was increased in oligodendrocytes both in the lesioned area and in the contralateral CA1-CA3 pyramidal cell layers and dentate gyrus. One week after needle-induced mechanical lesion an increase of labeled cells expressing CaSR mRNA was observed along the needle track. In conclusion the present results contribute to extend available data on cell type-expressing CaSR in normal and injured brain and could spur to understand the role of CaSR in repairing processes of brain injury.Receptors Calcium-SensingIbotenic acidDevelopmental BiologyAstrocyte
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Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.

2019

Abstract Background Our aim was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies and physical health outcomes associated with human immunodeficiency virus (HIV) but not acquired immunodeficiency syndrome. Methods We performed an umbrella review of observational studies. Evidence was graded as convincing, highly suggestive, suggestive, weak, or nonsignificant. Results From 3413 studies returned, 20 were included, covering 55 health outcomes. Median number of participants was 18 743 (range 403–225 000 000). Overall, 45 (81.8%) of the 55 unique outcomes reported nominally significant summary results (P < .05). O…

Microbiology (medical)medicine.medical_specialtyPopulationcomorbidHIV InfectionsDisease03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineAcquired immunodeficiency syndrome (AIDS)Meta-Analysis as TopicPre-EclampsiaPregnancyInternal medicineMedicineHumanshealth outcomes030212 general & internal medicineeducationArticles and CommentariesCOPDeducation.field_of_studyhuman immunodeficiency virusumbrella reviewbusiness.industryhuman immunodeficiency viruPublic healthIncidence (epidemiology)IncidenceAn Umbrella Review of Meta-analyses of Observational Studies.- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 [Grabovac I. Veronese N. Stefanac S. Haider S. Jackson S. Koyanagi A. Meilinger M. Stubbs B. Firth J. Soysal P. et al. -Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes]HIVmedicine.diseaseComorbidityObservational Studies as TopicInfectious DiseasesCross-Sectional StudiesAcademicSubjects/MED00290health outcomeFemalebusiness030217 neurology & neurosurgeryCohort studySystematic Reviews as TopicClinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Uguaglianza e diritto penale

2009

RICOSTRUZIONE DELLE DIVERSE PROSPETTIVE DEL PRINCIPIO DI UGUAGLIANZA DEL DIRITTO PENALE
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Le caratteristiche termofisiche del patrimonio edilizio della città di Palermo

2008

Un ambiente confinato è un rapporto continuo con il contesto bioclimatico esterno attraverso l'involucro edilizio, che notoriamente svolge una funzione di protezione e di filtro rispetto agli input esterni. Una corretta ottimizzazione della interfaccia edificio clima è legata, fra gli altri fattori, anche alla selezione di materiali le cui carayyeristiche termofisiche siano tali da agevolare il conseguimento della suddetta ottimizzazione. In particolare, la conoscenza del tempo di ritardo fra l'onda termica incidente e quella emergente all'interno dello spazio confinato, associata alla stima del fattore di attenuazione del flusso di calore, è presupposto di base per una corretta progettazio…

Settore ING-IND/11 - Fisica Tecnica Ambientalecaratteristiche termofisiche di componenti edilizi fabbisogni energetichi per diverse tipologie di edificio
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Radošās darbības veicināšanas iespējas 4 - 5 gadīgiem bērniem dizaina un tehnoloģiju nodarbībās

2021

Bakalaura darba temats: „Radošās darbības veicināšanas iespējas 4 - 5 gadīgiem bērniem dizaina un tehnoloģiju nodarbībās”. Bakalaura darba autore: Kristīne Reine Darba zinātniskā vadītāja: Dr. paed. Māra Urdziņa- Deruma Pētījuma mērķis: Pētīt 4 - 5 gadu vecu bērnu radošās darbības veicināšanas iespējas dizaina un tehnoloģiju rotaļnodarbībās. Pētījuma jautājums: Ar kādiem materiāliem un metodiskajiem paņēmieniem tiek veicināta radošā darbība dizaina un tehnoloģiju rotaļnodarbībās 4 - 5 gadīgiem bērniem. Pētījuma uzdevumi: 1.Analizēt literatūru par radošo darbību, tās veicināšanas iespējām. 2.Izzināt un analizēt 4 - 5 gadu vecu bērnu attīstības likumsakarības pētāmās problēmas aspektā. 3.Izzi…

Skolas pedagoģijadiverse materialsmethodological techniquespreschoolcreative activity
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Economic moralities in self-organised alternative economies : the Finnish cases of ridesharing and timebanking

2020

PurposeThis paper explores economic moralities in self-organised alternative economies and argues that the diverse economies approach is particularly useful in elaborating the self-understandings of such economic communities. The analysis focuses on two types of alternative economies in Finland: ridesharing and timebanking.Design/methodology/approachThrough qualitative data, the paper looks into moments of negotiation where economic moralities of self-organised alternative economies are explicitly debated. The main research data consists of social media conversations, supplemented by a member survey for the participants of the studied timebank. The data are analysed through theory-guided qu…

Sociology and Political Scienceaikapankitmedia_common.quotation_subject0211 other engineering and technologies0507 social and economic geographyQualitative propertyContext (language use)02 engineering and technologyridesharingMutually exclusive eventsalternative economiesvaihdantatalousEconomicsSocial mediaFinlandResearch datamedia_commondiverse economiestimebanks05 social sciences021107 urban & regional planningjakamistalousNegotiationEconomymoraaliyhteiskäyttöNormativetaloussosiologia050703 geographyGeneral Economics Econometrics and Financeeconomic moralitiesQualitative research
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