Search results for "dma"
showing 10 items of 315 documents
Visuospatial processing in schizophrenia: Does it share common mechanisms with pseudoneglect?
2011
International audience; ''Schizophrenia patients demonstrate behavioural and cerebral lateralised anomalies, prompting some authors to suggest they exhibit a mild form of right unilateral neglect. To better describe and understand lateralised visuospatial anomalies in schizophrenia, three experiments were run using tasks often utilised to study visuospatial processing in healthy individuals and in neglect patients: the Behavioural Inattention Test (BIT), the manual line bisection task with and without a local cueing paradigm, the landmark task (or line bisection judgement), and the number bisection task. Although the schizophrenia patients did not exhibit the full-blown neglect syndrome, th…
Evidence for cortical visual substitution of chronic bilateral vestibular failure (an fMRI study).
2007
Bilateral vestibular failure (BVF) is a rare disorder of the labyrinth or the eighth cranial nerve which has various aetiologies. BVF patients suffer from unsteadiness of gait combined with blurred vision due to oscillopsia. Functional MRI (fMRI) in healthy subjects has shown that stimulation of the visual system induces an activation of the visual cortex and ocular motor areas bilaterally as well as simultaneous deactivations of multisensory vestibular cortex areas. Our question was whether the chronic absence of bilateral vestibular input (BVF) causes a plastic cortical reorganization of the above-described visual-vestibular interaction. We used fMRI to measure the differential effects of…
A fatal paramethoxymethamphetamine intoxication.
2003
During the last years in Germany a marked increase in the use of amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) has been observed. The use of these recreational drugs is especially common among young people participating in rave parties. Occasionally ring-methoxylated phenethylamine derivatives like paramethoxymethamphetamine (PMMA) or paramethoxyamphetamine (PMA) are found in street drugs offered as ecstasy. These compounds exhibit a higher toxicity than the methylenedioxyamphetamine derivatives. We report on the death of a 22-year-old man after the ingestion of ecstasy pills containing PMMA and PMA. The PMMA concentration in femoral blood was 0.85 mg/l. Besides PMA…
Comparison of cyclodeviation and duction measurement in Graves' orbitopathy patients using different devices
2011
To compare measurement outcomes of different devices measuring cyclodeviation and ductions in Graves' orbitopathy (GO) patients. Cyclodeviation in GO patients was measured using the Harms tangent screen (HTS), the cycloforometer of Franceschetti, and the synoptometer. Ductions were measured using the modified perimeter, the Goldmann perimeter and the Maddox tangent scale (MTS). In 13 patients, cyclodeviation in primary position, up-, and downgaze was measured with the above-mentioned devices. The mean differences ranged from 0.3º to 3.1º and were smallest between the HTS and the cycloforometer (89% of all measurements within 2º difference). Measurement of abduction, adduction, elevation, an…
Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference.
2009
The present study employs a conditioned place preference procedure (CPP) to examine the effects of exposure to the cannabinoid agonist WIN 55212-2 (WIN) (0.1 and 0.5mg/kg) during adolescence on the reinforcing properties of +/-3,4-methylenedioxymetamphetamine hydrochloride (MDMA) (1.25 and 2.5mg/kg) in mice. On postnatal day (PD) 27, animals received a daily injection of the assigned treatment on 5 consecutive days, and three days later the place conditioning procedure was initiated (PD 35). The results suggest that pre-exposure to cannabinoids strengthens the properties of MDMA and favors reinstatement of the craving for the drug, which endorses the gateway hypothesis.
Kundmannia sicula (L.) DC: a rich source of germacrene D
2017
AbstractObjective: Kundmannia sicula is an herbaceous plant belonging to the family Apiaceae and is distributed in the Mediterranean coastal areas where it occurs in arid places. In this work, we have analysed the essential oil distilled from the aerial parts of K. sicula from Sicily (Italy) and its biological activity. Methods: GC-MS was used to analyze the chemical composition, whereas its antioxidant capacity and cytotoxicity on three human tumour cells (A375, MDA MB-231 and HCT 116) were evaluated by DPPH, ABTS, FRAP and MTT methods, respectively. Result: The essential oil resulted very rich of the sesquiterpene hydrocarbon germacrene D (81.2%). Moreover, the K. sicula oil displayed rel…
A comparison of the Canon TX-20P™ non-contact tonometer and pachymeter in healthy eyes
2012
Background: The aim of this study was to compare the intraocular pressure (IOP) and the central corneal thickness (CCT) measurements obtained with the Canon TX-20P™ with IOP measured with Goldmann applanation tonometer (GAT) and the CCT measured with ultrasound (US) pachymetry in healthy eyes. Methods: Thirty one healthy voluntary subjects participated in the study, age ranging from 16 to 81 years (mean age 50.9 years). In total 58 eyes were selected for analysis. All measurements were performed by the same examiner. The measurements were taken in the same order in all subjects: Canon IOP and CCT, Goldmann IOP and US CCT. Results: A strong correlation was found between IOP for both CCT comp…
Halloysite nanotubes filled with MgO for paper reinforcement and deacidification
2021
Abstract A novel material for the deacidification and protection of paper has been designed by using MgO filled halloysite nanotubes (Hal). The ability of MgO loaded nanotubes to control the acidic conditions was evaluated by pH measurements in aqueous solvent. Afterwards, paper was impregnated into hydroxypropyl cellulose dispersions containing the consolidating material. A simulation of strong acidic conditions allowed us to evaluate the deacidification effect of the composite material on the samples. In particular, the paper reaches a pH of 7.7 after 1 h exposition to HNO3 vapours when MgO-Hal nanoparticles are added to the impregnation mixture at a concentration of 10 wt% and it remains…
A Neural Solution for a Mobile Robot Navigation into Unknown Indoor Environments Using Visual Landmarks
1998
In this paper we present a neural solution for a mobile robot navigation into unknown indoor environments by using landmarks. Robot navigation task is implemented by two groups of processes based on MLP neural networks classifiers: a Low Level Vision System performs obstacle avoidance and corridor following, while an High Level Vision System extracts landmarks contents and performs goal directed navigation. A path-planner manages the two navigation systems and interacts with the robot hardware. The proposed solution is very strong and flexible and can be used to drive a mobile robot in real indoor environments. In the paper experimental results are also reported.
Insight into the noble crayfish morphological diversity: a geometric morphometric approach.
2022
The noble crayfish (Astacus astacus), a keystone species of high ecological, economic, and cultural importance in Europe, is threatened due to a long-term population decline caused by anthropogenic pressure on its habitats, the presence of non-indigenous invasive crayfish species and climate change. Since the effective protection of the remaining populations requires conservation measures based on the comprehensive knowledge of the species, including good understanding of its genetic and morphological variability, our aim was to study morphological features of the noble crayfish in Croatia using geometric morphometrics for the first time. We applied two-dimensional geometric morphometrics t…