Search results for "domain"
showing 10 items of 2485 documents
Nonlocalization Properties of Time Operators Transformations
2014
It is presented a general approach to the problem of extension of time operators and the associated Lambda transformations on singular measures. It is also shown that Lambda transformations defined on function spaces having the Urysohn property are non localized. Particular attention has been devoted to time and Lambda operators associated with the Walsh-Paley system and to a characterization of their domain and non locality.
Motivic Pattern Extraction in Symbolic Domain
2008
This chapter offers an overview of computational research in motivic pattern extraction. The central questions underlying the topic, concerning the formalization of the motivic structures, the matching strategies and the filtering of the results, have been addressed in various ways. A detailed analysis of these problems leads to the proposal of a new methodology, which will be developed throughout the study. One main conclusion of this review is that the problems cannot be tackled using purely mathematic or geometric heuristics or classical engineering tools, but require also a detailed understanding of the multiple constraints derived by the underlying cognitive context.
A marching-on in time meshless kernel based solver for full-wave electromagnetic simulation
2012
A meshless particle method based on an unconditionally stable time domain numerical scheme, oriented to electromagnetic transient simulations, is presented. The proposed scheme improves the smoothed particle electromagnetics method, already developed by the authors. The time stepping is approached by using the alternating directions implicit finite difference scheme, in a leapfrog way. The proposed formulation is used in order to efficiently overcome the stability relation constraint of explicit schemes. In fact, due to this constraint, large time steps cannot be used with small space steps and vice-versa. The same stability relation holds when the meshless formulation is applied together w…
Irreversible Inhibition of Epidermal Growth Factor Receptor Activity by 3-Aminopropanamides
2012
Irreversible epidermal growth factor receptor (EGFR) inhibitors contain a reactive warhead which covalently interacts with a conserved cysteine residue in the kinase domain. The acrylamide fragment, a commonly employed warhead, effectively alkylates Cys797 of EGFR, but its reactivity can cause rapid metabolic deactivation or nonspecific reactions with off-targets. We describe here a new series of irreversible inhibitors containing a 3-aminopropanamide linked in position 6 to 4-anilinoquinazoline or 4-anilinoquinoline-3- carbonitrile driving portions. Some of these compounds proved to be as efficient as their acrylamide analogues in inhibiting EGFR-TK (TK = tyrosine kinase) autophosphorylati…
Dissection of the relative contribution of the Schizosaccharomyces pombe Ctr4 and Ctr5 proteins to the copper transport and cell surface delivery fun…
2011
The Ctr1 family of proteins mediates high-affinity copper (Cu) acquisition in eukaryotic organisms. In the fission yeastSchizosaccharomyces pombe, Cu uptake is carried out by a heteromeric complex formed by the Ctr4 and Ctr5 proteins. Unlike human andSaccharomyces cerevisiaeCtr1 proteins, Ctr4 and Ctr5 are unable to function independently in Cu acquisition. Instead, both proteins physically interact with each other to form a Ctr4–Ctr5 heteromeric complex, and are interdependent for secretion to the plasma membrane and Cu transport activity. In this study, we usedS. cerevisiaemutants that are defective in high-affinity Cu uptake to dissect the relative contribution of Ctr4 and Ctr5 to the Cu…
Identification of a specific type of PD from acoustic emission frequency spectra
2001
The paper presents an attempt to apply spectral analysis tools in processing acoustic emission (AE) pulses generated by partial discharge (FD). The experimental part of the paper describes spark gaps generating four types of PD and specifies parameters of measured acoustic signals and recalls the system used for measurement and analysis of the frequency spectra. Also, a spectral analysis procedure is presented, and frequency-domain descriptors characterizing AE pulses are defined. The results of the analysis are given both as time plots and amplitude and energy density spectra, related to values of the associated descriptors. The spectral analysis results cover AE pulses generated in system…
Comparative analysis of acoustic emission signals generated by electrical discharges measured by the hydrophone and the wideband contact transducer
2005
The paper presents a comparative analysis of the acoustic emission (AE) pulses and signals generated by PDs. For this purpose the measurements of the acoustic emission signals generated by PDs were taken in the multipoint-plane system using a hydrophone placed directly in the area of discharge generation, and the AE pulses using a piezoelectric contact transducer which was on a side wall of a power transformer tub. Next, time runs and amplitude density spectra were drawn. Also the descriptors describing signals in the frequency domain were determined and the time-frequency analysis was carried out, which determined spectrograms for the energy density spectrum.
Investigating the level of significance of the coherence function in cardiovascular variability analysis
2002
Although the presence of significant coupling between cardiovascular variability series is usually verified according to the threshold value of 0.5 in the coherence function (CF), spectral estimator parameters should also be considered. In this study, the surrogate data technique was introduced to define the level of significance of the CF. The proposed method determined a frequency-dependent threshold over which the hypothesis of zero coherence was rejected. The weighted covariance method and the autoregressive method were used to estimate the CF on simulated series with different degrees of linear coupling and on real cardiovascular data. The threshold was dependent on the type and parame…
The Navier–Stokes equations in exterior Lipschitz domains: L -theory
2020
Abstract We show that the Stokes operator defined on L σ p ( Ω ) for an exterior Lipschitz domain Ω ⊂ R n ( n ≥ 3 ) admits maximal regularity provided that p satisfies | 1 / p − 1 / 2 | 1 / ( 2 n ) + e for some e > 0 . In particular, we prove that the negative of the Stokes operator generates a bounded analytic semigroup on L σ p ( Ω ) for such p. In addition, L p - L q -mapping properties of the Stokes semigroup and its gradient with optimal decay estimates are obtained. This enables us to prove the existence of mild solutions to the Navier–Stokes equations in the critical space L ∞ ( 0 , T ; L σ 3 ( Ω ) ) (locally in time and globally in time for small initial data).
A circular mesh scheme for the non-orthogonal finite difference time domain method
2002
Beam forming networks (BFN) are an important component of a complex satellite antenna system because they are used to provide accurate amplitude and phase excitation to the elements of the feed network. The need for handling high power and the need for a high degree of integrability, often leads one to choose square coaxial metal lines for constructing BFNs. BFNs usually require variable power dividers such as the rat-race (or ring) couplers with constant or variable divider ratios in order to deliver a prescribed amount of power to a certain element of an antenna array to steer the beam in a desired direction. However, modeling of such circular structures in square coaxial form is not an e…