Search results for "domes"
showing 10 items of 812 documents
Novel subpopulations in date palm (Phoenix dactylifera) identified by population-wide organellar genome sequencing
2019
Background The date palm is one of the oldest cultivated fruit trees. The tree can withstand high temperatures and low water and the fruit can be stored dry offering nutrition across the year. The first region of cultivation is believed to be near modern day Iraq, however, where and if the date palm was domesticated is still a topic of debate. Recent studies of chloroplast and genomic DNA revealed two major subpopulations of cultivars centered in both the Eastern range of date palm cultivation including Arabian Peninsula, Iraq and parts of South Asia, and the Western range, including North Africa. Results To better understand the origins of date palm cultivation we sequenced and analyzed ov…
AS4 message exchange protocol consolidation through the European CEF eDelivery infrastructure
2020
Since 2014, the European Union has supported the creation of cross-border communication networks based on an AS4 eDelivery solution through the Connecting Europe Facility. This article describes the current status of the uptake of the AS4 message exchange protocol in accordance with both the European infrastructure CEF eDelivery and the European regulation n°910/2014 on electronic identification and trust services for electronic transactions in the internal market. The main objective is to present an analysis of the achieved results from the implementation of the AS4 solution in several European projects carried out during the last 12 years to verify the impact of these projects around Euro…
Energy and economic analysis of air-to-air heat pumps as an alternative to domestic gas boiler heating systems in the South of Italy
2019
Abstract According to the electricity tariff recently issued by the Italian government for the domestic heating systems fed with heat pumps (HP), an energy and economic analysis was carried out with the aim of investigating the effectiveness of the air-to-air heat pump systems (HPS) as an alternative to the traditional heating using domestic gas boilers systems (GBS). For the purpose of this study, the apartments of three residential buildings were examined. The hourly heating loads were calculated with the ASHRAE radiant time series and the coefficient of performance (COP) of the HPs was evaluated for each operating condition. The costs for the heating system installation and electricity a…
Solar and Heat Pump Systems for Domestic Hot Water Production on a Small Island: The Case Study of Lampedusa
2020
The achievement of United Nations Sustainable Development Goals, related to energy and resource use, is a critical issue for small and insulated communities. In many minor islands, solar energy is not correctly exploited, and electrical heaters are connected to weak grids with very a high share of generation by fossil fuels. As a consequence, there is the necessity to assess the potential and the suitability of diffusion of alternative systems to avoid dependency on the electrical grid and reduce carbon emissions. This paper aims to evaluate the technical and economic performances of some alternative systems exploiting renewable energy for domestic hot water production. Four different syste…
Transteoretical Approaches on Domestic Violence
2019
Abstract Domestic violence is a widespread public health problem. Domestic violence does not just manifest itself physically, it can take different forms, from verbal aggression to insults of psychological, emotional, sexual, material deprivation or simply negligence. All these affect the victim in many ways. Thus, the professionals in medical, legal sciences, but also the state authorities with responsibilities in social protection and assistance must know the phenomenon very well and find the best ways to fight it. No institution will be able to achieve this objective by working individually, but only an efficient cooperation of all these factors can contribute to limiting the negative ef…
Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent
2019
Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in mode…
Refining the genetic structure and relationships of European cattle breeds through meta-analysis of worldwide genomic SNP data, focusing on Italian c…
2020
AbstractThe availability of genotyping assays has allowed the detailed evaluation of cattle genetic diversity worldwide. However, these comprehensive studies did not include some local European populations, including autochthonous Italian cattle. In this study, we assembled a large-scale, genome-wide dataset of single nucleotide polymorphisms scored in 3,283 individuals from 205 cattle populations worldwide to assess genome-wide autozygosity and understand better the genetic relationships among these populations. We prioritized European cattle, with a special focus on Italian breeds. Moderate differences in estimates of molecular inbreeding calculated from runs of homozygosity (FROH) were o…
Genome-wide association study reveals the locus responsible for microtia in Valle del Belice sheep breed.
2018
Microtia is a congenital deformity of the outer ear with phenotypes varying from a small auricle to total absence (anotia). The genetic basis is still poorly understood, and very few studies have been performed in sheep. Valle del Belice sheep is a breed showing microtia. The aim of this study was to identify the potential genomic regions involved in microtia in sheep. A total of 40 individuals, 20 with microtia and 20 normal, were genotyped with the Illumina OvineSNP50 BeadChip. The comparison among the results from a genome-wide association study, Fisher's exact test and FST analysis revealed a single strong association signal: rs419889303 on chromosome 1, located within intron 3 of the C…
Genome-wide association studies for milk production traits in Valle del Belice sheep using repeated measures
2019
Genome-wide association studies (GWASes) have become a powerful tool for identifying genomic regions associated with important traits in livestock. Milk production traits in dairy sheep are measured at different time points during their life span. Using phenotypic data generated from longitudinal traits could improve the power of association studies but until now have received less attention in GWASes as a methodology and has not been implemented. The aim of this study was to carry out a GWAS for milk production traits in Valle del Belice sheep using repeated measures. After quality control, 469 ewes and 37 228 SNPs were retained for the analysis, and phenotypic data included 5586 test-day …
The more the merrier? Scoring, statistics and animal welfare in experimental autoimmune encephalomyelitis.
2016
Experimental autoimmune encephalomyelitis (EAE) is a frequently used animal model for the investigation of autoimmune processes in the central nervous system. As such, EAE is useful for modelling certain aspects of multiple sclerosis, a human autoimmune disease that leads to demyelination and axonal destruction. It is an important tool for investigating pathobiology, identifying drug targets and testing drug candidates. Even though EAE is routinely used in many laboratories and is often part of the routine assessment of knockouts and transgenes, scoring of the disease course has not become standardized in the community, with at least 83 published scoring variants. Varying scales with diffe…