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showing 10 items of 8430 documents

The Randomized Shortened Dental Arch Study

2012

The scientific evidence concerning prosthodontic care for the shortened dental arch (SDA) is sparse. This randomized multicenter study aimed to compare two common treatment options: removable partial dental prostheses (RPDPs) for molar replacement vs. no replacement (SDA). One of the hypotheses was that the follow-up treatment differs between patients with RPDPs and patients with SDAs during the 5-year follow-up period. Two hundred and fifteen patients with complete molar loss in one jaw were included in the study. Molars were either replaced by RPDPs or not replaced according to the SDA concept. A mean number of 4.2 (RPDP) and 2.8 (SDA) treatments for biological or technical reasons occur…

AdultChange over timeMolarmedicine.medical_treatmentDentistryDental Abutmentslaw.inventionTooth LossDental ArchRandomized controlled triallawmedicineDenture Precision AttachmentHumansBicuspidProspective StudiesDenture DesignGeneral DentistryObservation timebusiness.industryJaw Edentulous PartiallyTreatment optionsDenture RetentionMolarDental archTreatment Outcomemedicine.anatomical_structureMulticenter studyDenture Partial RemovableProsthodonticsbusinessFollow-Up StudiesJournal of Dental Research
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15(S)-HETE modulates LTB(4) production and neutrophil chemotaxis in chronic bronchitis.

2000

We evaluated the levels of 15(S)-hydroxyeicosatetraenoic acid [15(S)-HETE] and the expression of 15-lipoxygenase (15-LO) mRNA in induced sputum obtained from 10 control and 15 chronic bronchitis subjects. 15(S)-HETE was evaluated by reverse phase high-performance liquid chromatography separation followed by specific RIA. 15-LO mRNA expression was determined by primed in situ labeling. The levels of both soluble and cell-associated 15(S)-HETE resulted significantly higher in chronic bronchitis than in control subjects. The percentage of cells expressing 15-LO mRNA was significantly higher in chronic bronchitis than in control subjects ( P < 0.01). Double staining for specific cell type ma…

AdultChronic bronchitisPhysiologyLeukotriene B4Cell SurvivalNeutrophilsNeutrophileCell CountLeukotriene B4chemistry.chemical_compoundHydroxyeicosatetraenoic AcidsMedicineArachidonate 15-LipoxygenaseHumansLung Diseases ObstructiveRNA MessengerBronchitisCells CulturedIn Situ HybridizationAgedbiologyIonophoresbusiness.industryMacrophagesSputumChemotaxisCell BiologyMiddle Agedmedicine.diseaseImmunohistochemistryChemotaxis Leukocytemedicine.anatomical_structureEicosanoidchemistryArachidonate 5-lipoxygenaseImmunologyChronic Diseasebiology.proteinBronchitisLeukotriene AntagonistsbusinessRespiratory tractAmerican journal of physiology. Cell physiology
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A new 3D method for measuring cranio-facial relationships with cone beam computed tomography (CBCT)

2013

Objectives: CBCT systems, with their high precision 3D reconstructions, 1:1 images and accuracy in locating cephalometric landmarks, allows us to evaluate measurements from craniofacial structures, so enabling us to replace the anthropometric methods or bidimensional methods used until now. The aims are to analyse cranio-facial relationships in a sample of patients who had previously undergone a CBCT and create a new 3D cephalometric method for assessing and measuring patients. Study Design: 90 patients who had a CBCT (i-Cat®) as a diagnostic register were selected. 12 cephalometric landmarks on the three spatial planes (X,Y,Z) were defined and 21 linear measurements were established. Using…

AdultCone beam computed tomographyAdolescentCephalometryBase (geometry)DentistryFacial BonesYoung AdultImaging Three-DimensionalBiomaterials and Bioengineering in DentistrymedicineHumansCraniofacialChildGeneral DentistryOrthodonticsbusiness.industrySkullMandibleCraniometryCone-Beam Computed TomographyMiddle AgedSkullmedicine.anatomical_structureOtorhinolaryngologySurgeryResearch-ArticlebusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Combination treatment with nefazodone and cognitive-behavioral therapy for relapse prevention in alcohol-dependent men: a randomized controlled study.

2004

Background This study evaluated the serotonergic antidepressant nefazodone versus placebo and specific cognitive-behavioral therapy (CBT) versus nondirective group counseling (GC) for relapse prevention in alcohol dependence in a large prospective, randomized, and placebo-controlled double-blind study at 3 German university centers. Method 242 male patients fulfilling at least 5 criteria for alcohol dependence according to DSM-IV and ICD-10 were eligible, after detoxification, for one of the following treatment combinations: nefazodone + CBT, nefazodone + GC, placebo + CBT, and placebo + GC. Either nefazodone or placebo was administered throughout the evaluation period of 15 months. Either …

AdultCounselingMalemedicine.medical_specialtymedicine.medical_treatmentRelapse preventionPlaceboPiperazineslaw.inventionGroup psychotherapyPlacebosRandomized controlled triallawInternal medicinemedicineSecondary PreventionHumansDiagnosis Computer-AssistedPsychiatryPsychiatric Status Rating ScalesCognitive Behavioral TherapyAlcohol dependenceTriazolesCombined Modality TherapyClinical trialCognitive behavioral therapyPsychiatry and Mental healthAlcoholismTreatment OutcomePsychologyNefazodonemedicine.drugThe Journal of clinical psychiatry
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Determination of periodontopathogens in patients with cri du chat syndrome

2013

Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level…

AdultCri-du-Chat SyndromeMaleendocrine systemmedicine.medical_specialtyCri du Chat syndromeAdolescentGingival and periodontal pocketCri du Chat SyndromeBleeding on probingSpecial care dentristyDentistryOdontologíaMicrobiologyYoung AdultInternal medicinemedicineHumansPeriodontal PocketPeriodontal healthTannerella forsythiaChildGeneral DentistryPeriodontitisBacteriabiologybusiness.industryPrevotella intermediaAggregatibacter actinomycetemcomitansTreponema denticola:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in Dentistrybiology.organism_classificationmedicine.diseaseCiencias de la saludstomatognathic diseasesOtorhinolaryngologyChild PreschoolUNESCO::CIENCIAS MÉDICASResearch-ArticleFemaleSurgerymedicine.symptombusinessMedicina Oral Patología Oral y Cirugia Bucal
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IQ differences between patients with first episode psychosis in London and Palermo reflect differences in patterns of cannabis use.

2019

Aims: Cognitive impairment is a possible indicator of neurodevelopmental impairment, but not all psychotic patients are cognitively compromised. It has been suggested that heavy cannabis use may precipitate psychosis in those who show no such compromise. This study compares two samples of patients with first-episode psychosis and their respective non-psychotic controls, in London (UK) and Palermo (Italy), and examines whether different patterns of cannabis use are reflected in differences in IQ. Methods: The two studies used the same inclusion/exclusion criteria and instruments. The sample comprised 249 subjects from London (106 patients and 143 controls) and 247 subjects from Palermo (120 …

AdultCross-Cultural ComparisonMalePsychosismedicine.medical_specialtyAdolescentIntelligenceNeurodevelopmentYoung Adult03 medical and health sciences0302 clinical medicineCognitionFirst episode psychosisLondonmedicineSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.HumansCognitive DysfunctionIn patientCannabiPsychiatryCognitive impairmentSettore MED/25 - PsichiatriaBiological PsychiatryMulticentric studybiologybusiness.industryConfoundingCognitionCannabis usemedicine.diseasebiology.organism_classification030227 psychiatryPsychiatry and Mental healthItalyPsychotic DisordersRisk factorsCase-Control StudiesFemaleMarijuana UseCannabisbusiness030217 neurology & neurosurgery
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Bacteria associated with periodontal disease are also increased in health.

2020

Background The objective of this cross-sectional clinical study was to analyze the differences in the microbiome in gingival sulci of adult patients in the presence or absence of chronic periodontitis. Material and Methods Patients with or without periodontal disease were included in this cross-sectional study. Subgingival biofilm samples were collected and analyzed by 16S massive pyrosequencing. Functional analyses were also performed. Results A total of 15 phyla, 154 genera and 351 species were detected globally. Differences between disease and non-disease samples were observed in all taxonomical levels which suggest functional profile changes in the community. It was found that the main …

AdultCross-sectional studyGingivaPhysiologyDiseaseTranscriptome03 medical and health sciences0302 clinical medicinemedicineHumansPeriodontologyMicrobiomeGeneral DentistrybiologyBacteriaResearchMicrobiotaBiofilm030206 dentistrymedicine.diseasebiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]Chronic periodontitisCross-Sectional StudiesOtorhinolaryngologyBiofilmsUNESCO::CIENCIAS MÉDICASChronic PeriodontitisPyrosequencingSurgeryBacteria
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Extraction of Impacted Maxillary Canines With Simultaneous Implant Placement

2005

When impacted maxillary canines are not amenable to orthodontic traction or reimplantation, extraction is the only option available, followed by implant placement. If apical and ridge crest bone remains after the extraction of the maxillary canines, an immediate implant can be placed. The implant is anchored bicortically with good primary fixation. This article presents a new surgical technique that allows an immediate implant placement after the extraction of the maxillary canines. The full circumference of the implant is left without bone coverage, except for the apical and coronal area. The implant screw threads and the bone defect are covered with the bone shavings collected by the filt…

AdultCuspidMaxillary sinusmedicine.medical_treatmentDentistryDental AbutmentsTransplantation AutologousSurgical FlapsDental AbutmentsMaxillaHumansMedicineTooth SocketOstectomyDental implantDental ImplantsOrthodonticsBone TransplantationCrownsImpactionbusiness.industryDental Implantation EndosseousDental prosthesisTooth ImpactedTransplantationmedicine.anatomical_structureOtorhinolaryngologyTooth ExtractionFemaleSurgeryDental Prosthesis Implant-SupportedImplantOral SurgerybusinessFollow-Up StudiesJournal of Oral and Maxillofacial Surgery
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Clinical and Microbiologic Effects of Subgingival Controlled-Release Delivery of Chlorhexidine Chip in the Treatment of Periodontitis: A Multicenter …

2008

Background: The main therapeutic approach for periodontal diseases is mechanical treatment of root surfaces via scaling and root planing (SRP). Multicenter clinical trials have demonstrated that the adjunctive use of a chlorhexidine (CHX) chip is effective in improving clinical results compared to SRP alone. However, some recent studies failed to confirm these clinical results, and conflicting results were reported regarding the effects of the CHX chip on subgingival microflora. The aim of this study was to provide further data on the clinical and microbiologic effects of CHX chips when used as an adjunct to SRP. Methods: A total of 116 systemically healthy individuals with moderate to adva…

AdultDNA BacterialMalemedicine.drug_classBleeding on probingColony Count MicrobialDental PlaqueDentistryStatistics Nonparametriclaw.inventionBacteria AnaerobicScaling and root planingAntisepticRandomized controlled triallawChlorhexidine/therapeutic use controlled clinical trial drug delivery system periodontitis/therapymedicineHumansSingle-Blind MethodperiodontitisAgedPeriodontitischlorexidine; periodontitis; periodontitis/therapy; controlled clinical trial; drug delivery systems; chlorhexidine/therapeutic usebusiness.industryChlorhexidineChlorhexidinePeriodontologyMiddle Agedmedicine.diseaseClinical trialDelayed-Action PreparationsMultivariate AnalysisAnti-Infective Agents LocalDental ScalingPeriodonticsFemalePeriodontal Indexmedicine.symptombusinessmedicine.drugJournal of Periodontology
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Bone-to-implant contact of orthodontic implants in humans--a histomorphometric investigation

2008

The purpose of the present study was to evaluate the percentage of direct bone-to-implant contact (BIC) of orthodontic anchorage implants (Orthosystem) after active orthodontic treatment. Twenty orthodontic implants (diameter, 3.3 mm; length, 4 or 6 mm) were inserted for orthodontic anchorage in different anatomical regions of 18 adult patients (nine males, nine females) aged 18-63 years. Fifteen implants (one per patient) were placed in the mid-palatal area, one implant (one patient) in the retromolar area of the mandible, one in the retromolar area and the mid-palatal area (one patient), and two (bilaterally, one patient) in the zygomatic area. The duration of the unloaded healing period …

AdultDental Stress AnalysisMalePalate HardAdolescentDentistryOrthodonticsOrthodontics CorrectiveOsseointegrationYoung AdultOsseointegrationOrthodontic Anchorage ProceduresmedicineHumansDevice RemovalDental ImplantsOrthodonticsWound HealingAdult patientsbusiness.industryDental Implantation EndosseousMandibleMiddle Agedmedicine.diseaseOrthodontic Anchorage ProceduresBone to implant contactRetromolar areaFemaleImplantMalocclusionbusinessMalocclusionThe European Journal of Orthodontics
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