Search results for "don"

showing 10 items of 8430 documents

The assesment of relationship between the angulation of impacted mandibular third molar teeth and the thickness of lingual bone: A prospective clinic…

2018

Background Our purpose was to investigate the relationship between the angulation of mandibular third molars and the thickness of the lingual bone, which can affect the risk of lingual nerve damage during lower third molars surgical extraction. Material and Methods This study consisted of 104 patients (42 males and 62 females), aged between 18-42 years (24.67 ± 6.11 years). Cone Beam Computed Tomography (CBCT) images were taken for preoperative assessment. The teeth were divided into four groups according to their positions: mesioangular, distoangular, vertical and horizontal. Lingual bone thickness around impacted teeth were measured at three points: cementoenamel junction (CEJ) of the man…

AdultMale0301 basic medicineMolarCone beam computed tomographyAdolescentMandibleMandibular second molarMandibular third molarLingual Nerve InjuriesYoung Adult03 medical and health sciences0302 clinical medicinestomatognathic systemHumansMedicineProspective StudiesIntraoperative ComplicationsGeneral DentistryLingual nerveOrthodonticsbusiness.industryImpacted toothResearchHyoid BoneTooth ImpactedMandible030206 dentistry:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesCementoenamel junctionOtorhinolaryngologyTooth ExtractionUNESCO::CIENCIAS MÉDICASFemaleMolar ThirdSurgery030101 anatomy & morphologyOral SurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Association of CYP2R1 rs10766197 with MS risk and disease progression

2017

Background MS is a neurodegenerative autoimmune disease resulting from a complex interaction of genetic and environmental factors. Among these, vitamin D and genetic variants associated with vitamin D-metabolism gain great attention. The aim of our study was to assess five SNPs in NADSYN1 and CYP2R1 genes in relation to serum 25-OH-vitamin D3 levels in MS patients and controls. Methods 25-OH-vitamin D3 levels and genotyping of CYP2R1- and NADSYN1-SNPs were investigated both in MS patients and in healthy controls. Results The analysis revealed lower 25-OH-vitamin D3 concentrations in MS patients than in controls and an association of rs10766197 CYP2R1 SNP with MS risk. After stratifying MS p…

AdultMale0301 basic medicineOncologymedicine.medical_specialtyPathologyMultiple SclerosisGenotypeSingle-nucleotide polymorphismPolymorphism Single NucleotideSeverity of Illness IndexpolymorphismDisability Evaluation03 medical and health sciencesCellular and Molecular NeuroscienceSex Factors0302 clinical medicineInternal medicinegendermedicineVitamin D and neurologyHumansSNPGenetic Predisposition to DiseaseNADSYN1AlleleCytochrome P450 Family 2GenotypingRetrospective Studiesbusiness.industryMultiple sclerosisCase-control studyvitamin dMiddle Agedmedicine.diseaseMinor allele frequency030104 developmental biologyCase-Control Studiesmultiple sclerosiDisease ProgressionCYP2R1Cholestanetriol 26-MonooxygenaseFemaleCarbon-Nitrogen Ligases with Glutamine as Amide-N-Donorgeneticbusiness030217 neurology & neurosurgeryJournal of Neuroscience Research
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Erratum to: Donor age and long-term culture do not negatively influence the stem potential of limbal fibroblast-like stem cells

2016

In regenerative medicine the maintenance of stem cell properties is of crucial importance. Ageing is considered a cause of reduced stemness capability. The limbus is a stem niche of easy access and harbors two stem cell populations: epithelial stem cells and fibroblast-like stem cells. Our aim was to investigate whether donor age and/or long-term culture have any influence on stem cell marker expression and the profiles in the fibroblast-like stem cell population.Fibroblast-like stem cells were isolated and digested from 25 limbus samples of normal human corneo-scleral rings and long-term cultures were obtained. SSEA4 expression and sphere-forming capability were evaluated; cytofluorimetric…

AdultMale0301 basic medicineStage-Specific Embryonic AntigensPrimary Cell CultureGene ExpressionMedicine (miscellaneous)Limbus CorneaeBiologyBiochemistry Genetics and Molecular Biology (miscellaneous)Donor age03 medical and health sciencesCell MovementSpheroids CellularmedicineATP Binding Cassette Transporter Subfamily G Member 2HumansFibroblastAgedCell ProliferationStem CellsAge FactorsEpithelium CornealCell DifferentiationEpithelial CellsHLA-DR AntigensNanog Homeobox ProteinCell BiologyFibroblastsMiddle AgedMolecular medicinehumanitiesNeoplasm ProteinsCell biology030104 developmental biologymedicine.anatomical_structureLeukocyte Common AntigensMolecular MedicineFemaleErratumStem cellOctamer Transcription Factor-3BiomarkersStem Cell Research & Therapy
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Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors

2016

Increasing evidence indicates that chronic stress, such as social isolation, plays an important role in the development of a variety of psychiatric and somatic disorders. Meanwhile, chronic stress imposed by prolonged isolation and confinement in the spacecraft is also one of the major concerns for the health of future interplanetary space travelers. Preclinical studies suggest that the peripheral endocannabinoid (eCB) system is involved in the regulation of the stress response and eCB signaling is implicated in the pathogenesis of stress-related diseases. However, there are only few human studies addressing this topic, of which most focusing on patients who have already developed a certain…

AdultMale0301 basic medicinemedicine.medical_specialty2-ArachidonoylglycerolArachidonic AcidsGlyceridesPathogenesis03 medical and health scienceschemistry.chemical_compoundCatecholamines0302 clinical medicineTandem Mass SpectrometrymedicineHumansChronic stressSocial isolationPsychiatryChromatography High Pressure LiquidBiological PsychiatryPsychiatric Status Rating ScalesPharmacologyStressorBrainElectroencephalographyAnandamideEndocannabinoid systemHealthy Volunteers030104 developmental biologychemistryLinear ModelsCatecholamineFemalemedicine.symptomPsychologyNeuroscienceStress Psychological030217 neurology & neurosurgeryEndocannabinoidsmedicine.drugProgress in Neuro-Psychopharmacology and Biological Psychiatry
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Aluminum Chloride versus Electrocauterization in Periapical Surgery: A Randomized Controlled Trial

2019

The aim of this study was to evaluate the efficacy of 2 hemostatic agents in periapical surgery and its relationship with patient- and tooth-dependent variables.A prospective study was designed with 2 randomized parallel groups established according to the hemostatic agent used: aluminum chloride or electrocauterization. The surgeon and 2 independent blinded observers examined the initial and final bleeding and recorded it as 0 (no hemorrhage control), 1 (slight but apparent intermittent bleeding), or 2 (complete hemorrhage control). The following patient- and tooth-dependent variables were collected: sex, age, smoking habit, plaque index, and position.Sixty patients with a periapical lesio…

AdultMale0301 basic medicinemedicine.medical_specialtyPlaque indexHemostaticsEndodonticslaw.invention03 medical and health sciencesSex Factors0302 clinical medicineRandomized controlled triallawFemale patientElectrocoagulationmedicineAluminum ChlorideHumansProspective StudiesProspective cohort studyGeneral Dentistrybusiness.industryPeriapical Diseases030206 dentistryMiddle AgedHemostasis SurgicalSurgeryTreatment Outcome030104 developmental biologyMale patientHemorrhage controlFemaleElectrocauterizationbusinessPeriapical surgeryJournal of Endodontics
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Is telephone follow-up really effective in early diagnosis of inflammatory complications after tooth extraction?

2018

Background To establish whether telephone follow-up is really able to intercept post-extraction complications and to evaluate the degree of patient satisfaction with this kind of post-surgical monitoring. Material and Methods Six hundred and thirty-eight patients were enrolled and randomly assigned to a test or control group. Test group patients were monitored by telephone follow-up 24 and 72 hours after surgery to investigate the presence of local symptoms that are frequently associated with surgical wound infection and inflammation. Both test and control group patients were examined 7 days at suture removal. Patients with systemic diseases, those in which intra-operative accidents occurre…

AdultMale0301 basic medicinemedicine.medical_specialtycomplicationsoral surgery; complications; telephone follow-upDehiscencelaw.inventionSettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE03 medical and health sciencesPostoperative ComplicationsPatient satisfactionRandomized controlled trialSuture (anatomy)lawtelephone follow-upHumansSurgical Wound Infectionfollow upMedicineAntibiotic prophylaxisGeneral DentistryInflammationbusiness.industryResearchSurgical wound:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseTelephoneSurgeryEarly DiagnosisOtorhinolaryngologyPatient SatisfactionTooth ExtractionUNESCO::CIENCIAS MÉDICASFemaleSurgery030101 anatomy & morphologyOsteitisbusinessComplicationFollow-Up Studiesoral surgeryMedicina Oral Patología Oral y Cirugia Bucal
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Assessment of tensile mechanical properties of the Achilles tendon in adult patients with haemophilic arthropathy.

2019

AdultMale030204 cardiovascular system & hematologyAchilles TendonBiomechanical Phenomena03 medical and health sciences0302 clinical medicineTensile StrengthHemarthrosisUltimate tensile strengthHumansMedicineGenetics (clinical)OrthodonticsHaemophilic arthropathyReproducibilityAchilles tendonAdult patientsbusiness.industryHematologyGeneral MedicineBiomechanical Phenomenamedicine.anatomical_structureFemalebusiness030215 immunologyHaemophilia
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Assessing Planning Ability Across the Adult Life Span in a Large Population-Representative Sample: Reliability Estimates and Normative Data for the T…

2019

AbstractObjectives:The Tower of London (TOL) test has probably become the most often used task to assess planning ability in clinical and experimental settings. Since its implementation, efforts were made to provide a task version with adequate psychometric properties, but extensive normative data are not publicly available until now. The computerized TOL-Freiburg Version (TOL-F) was developed based on theory-grounded task analyses, and its psychometric adequacy has been repeatedly demonstrated in several studies but often with small and selective samples.Method:In the present study, we now report reliability estimates and normative data for the TOL-F stratified for age, sex, and education …

AdultMale050103 clinical psychologyHuman DevelopmentApplied psychologyNormative dataLarge populationTower of LondonSample (statistics)Neuropsychological TestsGutenberg Health Study (GHS)Task (project management)Cohort StudiesExecutive Function03 medical and health sciences0302 clinical medicineReference ValuesGermanyHumans0501 psychology and cognitive sciencesReliability (statistics)AgedAged 80 and overRegular Researchorganic chemicalsGeneral Neuroscience05 social sciencesReproducibility of ResultsMiddle AgedReliabilityTest (assessment)PlanningPsychiatry and Mental healthClinical PsychologyAdult lifeTOL-FbacteriaNormativeFemaleNeurology (clinical)PsychologyTower030217 neurology & neurosurgeryJournal of the International Neuropsychological Society
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The Importance of Considering Alexithymia during Initial Stages of Intimate Partner Violence Interventions to Design Adjuvant Treatments

2019

Empirical evidence supports that individuals with alexithymia might be prone to certain types of violence, such as intimate partner violence against women (IPVAW). Moreover, considering that alexithymia is directly involved in behavior regulation, problems due to identifying and regulating emotional states might be postulated as responsible, at least in part, for the success of psychotherapeutic treatments designed for decreasing the future risk of reoffending. Therefore, we assessed whether alexithymia was a good predictor of the discontinuation of treatment (dropout) and the risk of recidivism during the initial stages of intervention in a sample of men convicted of IPVAW perpetration (n …

AdultMale050103 clinical psychologydrug misuseHealth Toxicology and MutagenesisEmotionsPsychological interventionPoison controlIntimate Partner Violencelcsh:MedicineImpulsivitydropoutArticle03 medical and health sciences0302 clinical medicineAlexithymiaInjury preventionmedicineHumans0501 psychology and cognitive sciencesAffective Symptomsintimate partner violence against womenRecidivism05 social scienceslcsh:RPublic Health Environmental and Occupational HealthreoffendingHuman factors and ergonomicsMiddle AgedDones maltractadesmedicine.diseaseSocioeconomic FactorsDomestic violencemedicine.symptomDroguesalexithymiaPsychology030217 neurology & neurosurgeryClinical psychologyInternational Journal of Environmental Research and Public Health
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Cephalometric measurements from 3D reconstructed images compared with conventional 2D images

2011

Abstract Objective: To assess whether the values of different measurements taken on three-dimensional (3D) reconstructions from cone-beam computed tomography (CBCT) are comparable with those taken on two-dimensional (2D) images from conventional lateral cephalometric radiographs (LCRs) and to examine if there are differences between the different types of CBCT software when taking those measurements. Material and Methods: Eight patients were selected who had both an LRC and a CBCT. The 3D reconstructions of each patient in the CBCT were evaluated using two different software packages, NemoCeph 3D and InVivo5. An observer took 10 angular and 3 linear measurements on each of the three types o…

AdultMale2d imagesAdolescentCephalometryRadiographyDentistryOrthodonticsComputed tomographyImage processingMandibleYoung AdultImaging Three-DimensionalImage Processing Computer-AssistedMaxillamedicineHumansNasal BoneSella TurcicaChildMathematicsObserver VariationOrthodonticsmedicine.diagnostic_testPalatebusiness.industryIntraobserver reliabilityReproducibility of ResultsOriginal ArticlesCone-Beam Computed TomographyIncisorFaceMandibular planeFemalebusinessObserver variationSoftwareThe Angle Orthodontist
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