Search results for "drosophila"

Analysis of two not yet described member of the SLC7 family of amino acid antiporters in Drosophila melanogaster

2015

Analysis of two not yet described member of the SLC7 family of amino acid antiporters in Drosophila melanogaster. 16. rencontre du Club de neurobiologie des invertébrés

Amino acid transporter heavy chain CD98hc: Expression and role in Drosophila olfactory perception

2015

Amino acid transporter heavy chain CD98hc: Expression and role in Drosophila olfactory perception. 16. rencontre du Club de neurobiologie des invertébrés

Accelerated bang recovery in Drosophila genderblind mutants

2008

International audience; Cystine-glutamate transporters import cystine into cells for glutathione synthesis and protection from oxidative stress, but also export significant amounts of glutamate. Increasing evidence suggests that 'ambient extracellular glutamate' secreted by cystine-glutamate transporters in the nervous system modulates glutamatergic synapse strength and behavior. To date, the only cystine-glutamate transporter mutants examined behaviorally are Drosophila genderblind mutants. These animals contain loss-of-function mutations in the 'genderblind' gene, which encodes an xCT subunit essential for cystine-glutamate transporter function. Genderblind was named based on a mutant cou…

An olfactory circuit for fruit-derived odours promotes courtship in male Drosophila

2010

Direct sensing of leucine by insulin-producing neurons

2015

Direct sensing of leucine by insulin-producing neurons. MoucheRhône

serrano gene and NaCl perception

2010

Gustatory information is considered to be important for animals to control behavior when they seek for food or partners. 60 members of gustatory receptor (Gr) genes have been identified in Drosophila.. However little is now about mechanisms of taste perception and transduction in response to stimuli. In order to identify new genes involved in gustation, we performed a genetic screen using Gal4-UAS system based on expression of the reporter gene in chemosensory organs and gustatory defects in larvae and adults. We identified the serrano (sano) gene, which encodes a 778 aa protein with a leucine zipper domain, a putative transmembrane domain, and putative bipartite nuclear localization signal…

Structural and enzymatic characterization of a Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to …

2016

Glutathione transferases (GSTs) are ubiquitous key detoxification enzymes that catalyze the conjugation of glutathione to a large variety of xenobiotic chemical including odorants and sapid molecules. A previous study in Drosophila melanogaster demonstrated the existence of a GST specifically expressed in the antenna and involved in signal termination by catalyzing biotransformation of odorant molecules. Genomic analysis allows identifying forty GSTs in Drosophila melanogaster but their biochemistry is poorly documented. Here we demonstrated that among the GSTs, dmelGSTD2-2 was strongly and preferentially overexpressed in the sensory organs (antennae, proboscis, legs, wings) after an exposu…

Réponses comportementales et préférences envers les acides gras à longue chaîne chez Drosophila melanogaster

2011

Fatty-acids (FAs) are crucial for animal survival and reproduction since these molecules are involved in many metabolic pathways and constitute a substantial store of energy. Despite the strong relationship established between excessive FA consumption and severe human etiologies (obesity, cancer, vascular diseases), our knowledge of the mechanisms underlying FA perception and preference is limited particularly in invertebrates. This is one of the reasons why we decided to investigate, during our PhD thesis, the perception of long-chain FAs (C14:0, C16:0, C18:0, C18:1, C18:2, C18:3), using the model species Drosophila melanogaster. We have also attempted to characterize some of the biologica…

Pheromonal imprinting in Drosophila melanogaster: preadult exposure affects free flight odor tracking in adult

2021

International audience

Terminal tendon cell differentiation requires the glide/gcm complex.

2004

International audience; Locomotion relies on stable attachment of muscle fibres to their target sites, a process that allows for muscle contraction to generate movement. Here, we show that glide/gcm and glide2/gcm2, the fly glial cell determinants, are expressed in a subpopulation of embryonic tendon cells and required for their terminal differentiation. By using loss-of-function approaches, we show that in the absence of both genes, muscle attachment to tendon cells is altered, even though the molecular cascade induced by stripe, the tendon cell determinant, is normal. Moreover, we show that glide/gcm activates a new tendon cell gene independently of stripe. Finally, we show that segment p…