Search results for "duch"
showing 10 items of 141 documents
Properties of New Strawberry Lines Compared with Well-Known Cultivars in Winter Planting System Conditions
2017
In Southern Italy and Sicily, strawberry cultivation is dominated by international cultivars such as ‘Candonga Sabrosa’, ‘Florida Fortuna’, ‘Sabrina’ and ‘Sant Andreas’. The primary objective of our study was to compare the field performance of two experimental lines and four established cultivars in a Sicilian representative strawberry production area. The second objective was to compare the fruits physic-chemical nutraceutical characteristics of these genotypes in response to different postharvest fruit storage temperatures. A supporting genetic analysis, via SSR markers, was also performed in order to establish genotype correlations. Our study confirmed the high result of ‘Florida Fortun…
Afinidades entre la arquitectura y la música. Algunas reflexiones
2019
Autism spectrum disorders in children affected by Duchenne muscular dystrophy
2018
Background Duchenne muscular dystrophy (DMD) is the most frequent and severe form of the dystrophinopathies. The literature shows that about 30-40% of DMD subjects have intellectual disability. In males with Duchenne muscular dystrophy, neuropsychiatric disorders have also been observed: attention deficit disorder and hyperactivity, autism spectrum disorders, and obsessive-compulsive disorder. Duchenne muscular dystrophy is not just a muscle disorder, but also a disease that affects the brain. The aim of the present study was to describe a case series of children with Duchenne muscular dystrophy that have also the presence of autism spectrum disorders (ASDs). They have been assessed by mean…
Beneficial Role of Exercise in the Modulation of
2021
Duchenne muscular dystrophy (DMD) is an X-linked recessive progressive lethal disorder caused by the lack of dystrophin, which determines myofibers mechanical instability, oxidative stress, inflammation, and susceptibility to contraction-induced injuries. Unfortunately, at present, there is no efficient therapy for DMD. Beyond several promising gene- and stem cells-based strategies under investigation, physical activity may represent a valid noninvasive therapeutic approach to slow down the progression of the pathology. However, ethical issues, the limited number of studies in humans and the lack of consistency of the investigated training interventions generate loss of consensus regarding …
Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress
2016
Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e. unfolded protein response (UPR), play key roles in proteostasis but their involvement in the pathology of DMD are largely unknown. Moreover, exercise and activin receptor IIB blocking are two strategies that may be beneficial to DMD muscle, but studies to examine their effects on these proteostasis pathways are lacking. Therefore, these pathways were examined in the muscle of mdx mice, …
La desamortización y enajenación del dominio de Sueca a finales del antiguo régimen: la presencia de Godoy como duque y señor de Sueca
2010
La concesión del ducado de Sueca a Manuel Godoy y la adquisición, mediante pública subasta del término y las pertenencias de esta villa, provocó importantes cambios en la jurisdicción y administración de la anterior posesión de la Orden de Montesa. La modificación en las condiciones de la compra, confirieron al Príncipe de la Paz los mismos privilegios de los que disfrutaba el Rey como Gran Maestre y Administrador Perpetuo, lo que acabó generando tensiones con los vecinos, terratenientes y el propio Ayuntamiento. The granting of the Duchy of Sueca to Manuel Godoy and the acquisition by auction of the territory and the belongings of this town, led to significant changes in the jurisdiction a…
Lack of Dystrophin Affects Bronchial Epithelium in mdx Mice
2016
Mild exercise training may positively affect the course of Duchenne Muscular Dystrophy (DMD). Training causes mild bronchial epithelial injury in both humans and mice, but no study assessed the effects of exercise in mdx mice, a well known model of DMD. The airway epithelium was examined in mdx (C57BL/10ScSn-Dmdmdx) mice, and in wild type (WT, C57BL/10ScSc) mice either under sedentary conditions (mdx-SD, WT-SD) or during mild exercise training (mdx-EX, WT-EX). At baseline, and after 30 and 45 days of training (5 d/wk for 6 weeks), epithelial morphology and markers of regeneration, apoptosis, and cellular stress were assessed. The number of goblet cells in bronchial epithelium was much lower…
Gone to smelt iron in Courland: technology transfer in the development of an early modern industry
2019
SUMMARY: In the Duchy of Courland and Semigallia, corresponding to the southern and western parts of present-day Latvia, an iron industry based on blast-furnace technology, mainly using local bog iron ore, existed in the 17th and 18th centuries. Transfer of knowledge and skill through the recruitment of specialists from other countries of Europe was crucial to the development of this industry; technology was also re-exported to Russia and elsewhere. Recent archaeological and archaeometallurgical investigations supplement the written evidence, highlighting the specific local conditions that influenced the development of ferrous metalworking here in the early modern period. This article will …
Niepokojący wschód azjatyckiej teologii. Wprowadzenie do studium
2021
Teologia w Polsce nie dysponuje tłumaczeniami ani opracowaniami w zakresie teologii i duchowości azjatyckiej. W dodatku na płaszczyźnie pastoralnej kontakt z Dalekim Wschodem nacechowany jest lękiem, wynikającym z braku wiedzy. Instytut badań nad Teologią i Duchowością Dalekiego Wschodu jest próbą odpowiedzi na zapotrzebowanie integracji środowiska naukowego, zajmującego się teologią i duchowością Dalekiego Wschodu. Niniejsza publikacja jest zaproszeniem do współpracy.
Autism spectrum disorders in children affected by Duchenne Muscular Dystrophy
2019
Objective Duchenne Muscular Dystrophy (DMD) is a progressive neuromuscular condition that has a high rate of cognitive and learning disabilities as well as neurobehavioral disorders, some of which have ben associated with disruption of dystrophin isoforms. Recent studies have pointed to an increased risk for intellectual disability and autism among affected males.The aim of the present study was to describe a case series of children with DMD that have also the presence of autism spectrum disorders (ASDs). they have been assessed by means of standardized autism scales and the monst appropriate psycho-educational treatment is herein discussed. Methods and Results In order to evaluate and iden…