Search results for "dynamics"
showing 10 items of 9782 documents
Spontaneous Spatiotemporal Ordering of Shape Oscillations Enhances Cell Migration
2019
The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence collective properties. Here we demonstrate, using numerical simulations, that the interplay of directed motion, shape oscillations, and excluded volume enables cells to locally "synchronize" their motion and thus enhance collective migration. Our model captures elongation and contraction of crawling ameboid cells controlled by an internal clock with a fixed period, mimicking the internal cycle of biological cells. We show that shape oscillations are crucial f…
Flow properties and hydrodynamic interactions of rigid spherical microswimmers.
2017
We analyze a minimal model for a rigid spherical microswimmer and explore the consequences of its extended surface on the interplay between its self-propulsion and flow properties. The model is the first order representation of microswimmers, such as bacteria and algae, with rigid bodies and flexible propelling appendages. The flow field of such a microswimmer at finite distances significantly differs from that of a point-force (Stokeslet) dipole. For a suspension of microswimmers, we derive the grand mobility matrix that connects the motion of an individual swimmer to the active and passive forces and torques acting on all the swimmers. Our investigation of the mobility tensors reveals tha…
The effect of the internal architecture of polymer micronetwork colloids on the dynamics in highly concentrated dispersions
2007
Motivated by the finding that colloidal dispersions of polymer micronetwork spheres with a cross-link density of 1:50 (inverse number of monomer units between crosslinks) show significant deviations from the dynamics of hard spheres in the colloid glass as seen by dynamic light scattering (DLS) (E. Bartsch, V. Frenz, H. Sillescu J. Non — Cryst. Solids 172–174 (1994), 88–97), we have undertaken a systematic study of the effect of the crosslink density on the dynamics at high concentrations. Long-time self-diffusion coefficients D S L and collective diffusion coefficients D c were measured for colloids with crosslink densities of 1:10, 1:20 and 1:50 by forced Rayleigh scattering (FRS) and the…
Evaluation of ABC gene polymorphisms on the pharmacokinetics and pharmacodynamics of capecitabine in colorectal patients: Implications for dosing rec…
2020
Aims The aims are to develop a population pharmacokinetic model of capecitabine (CAP) and its main metabolites after the oral administration of CAP in colorectal cancer patients with different polymorphisms of the ATP-binding cassette (ABC) gene and a population pharmacokinetic/pharmacodynamic model capable of accounting for the neutropenic effects, and to optimize the dosing strategy based on the polymorphisms of the ABC gene and/or the administration regimen as a single agent or in combination. Methods Forty-eight patients diagnosed with colorectal cancer were included, with 432 plasma levels of CAP, 5'-desoxi-5-fluorouridine (5'-DFUR) and 5-fluorouracil (5-FU), and 370 neutrophil observa…
Thermodynamic stability of non-stoichiometric SrFeO 3−δ : a hybrid DFT study
2019
SrFeO3-δ is mixed ionic-electronic conductor with complex magnetic structure which reveals also colossal magnetoresistance effect. This material and its solid solutions are attractive for various spintronic, catalytic and electrochemical applications, including cathodes for solid oxide fuel cells and permeation membranes. Its properties strongly depend on oxygen non-stoichiometry. Ab initio hybrid functional approach was applied here for a study of thermodynamic stability of a series of SrFeO3-δ compositions with several non-stoichiometries δ, ranging from 0 to 0.5 (SrFeO3 - SrFeO2.875 - SrFeO2.75 - SrFeO2.5) as the function of temperature and oxygen pressure. The results obtained by consid…
Thermodynamics of ABO3-Type Perovskite Surfaces
2011
The ABO3-type perovskite manganites, cobaltates, and ferrates (A= La, Sr, Ca; B=Mn, Co, Fe) are important functional materials which have numerous high-tech applications due to their outstanding magnetic and electrical properties, such as colossal magnetoresistance, half-metallic behavior, and composition-dependent metal-insulator transition (Coey et al., 1999; Haghiri-Gosnet & Renard, 2003). Owing to high electronic and ionic conductivities. these materials show also excellent electrochemical performance, thermal and chemical stability, as well as compatibility with widely used electrolyte based on yttrium-stabilized zirconia (YSZ). Therefore they are among the most promising materials as …
Symbolic Dynamics of Geodesic Flows on Trees
2019
In this chapter, we give a coding of the discrete-time geodesic ow on the nonwandering sets of quotients of locally finite simplicial trees X without terminal vertices by nonelementary discrete subgroups of Aut(X) by a subshift of finite type on a countable alphabet.
Novel patterns for vector mesons from the large-Nc limit
2008
We report on a relation between the decay constants of \rho-like J^{PC}=1^{--} vector mesons, which arises solely from the perturbative analysis of the VV, TT and VT correlators at order \alpha_s^0 in the large-N_c limit. We find f_{V}^T/f_{V}=1/\sqrt{2} for highly excited states together with a pattern of alternation in sign. Quite remarkably, recent lattice determinations reported f_{\rho}^T/f_{\rho}=0.72(2), in excellent agreement with our large-N_c result. This seems to suggest a pattern like f_{Vn}^T/f_{Vn}=(-1)^n/\sqrt{2} for the whole (1^{--}) states. In order to test this conjecture in real QCD we construct a set of spectral sum rules, which turn out to comply nicely with this scena…
Entropy, transverse entropy and partitions of unity
1994
AbstractThe topological entropy of a transformation is expressed in terms of partitions of unity. The transverse entropy of a flow tangential to a foliation is defined and expresed in a similar way. The geometric entropy of a foliation of a Riemannian manifold is compared with the transverse entropy of its geodesic flow.
The dynamics of online news discussions: effects of news articles and reader comments on users’ involvement, willingness to participate, and the civi…
2017
ABSTRACTThis study investigates when and why news website visitors write civil or uncivil comments in response to news articles or related user comments. In an experiment, we manipulated the news value of news articles and the presence of ‘deliberative’ or ‘detrimental’ elements of comments to compare their impact on participants’ involvement, willingness to comment, and the comments they posted. News factors and comment characteristics increased participants’ willingness to comment via cognitive and affective involvement. Cognitive involvement made it less likely and affective involvement more likely that participants wrote uncivil comments. Additionally, involvement with previous comments…