Search results for "e learning"
showing 10 items of 2703 documents
Glucose plus choline improve passive avoidance behaviour and increase hippocampal acetylcholine release in mice.
2001
The present study tests the effects of glucose and choline, the biosynthetic precursors of acetylcholine, on passive avoidance behaviour and hippocampal acetylcholine release measured by microdialysis in awake mice. Glucose (10 and 30mg/kg) or choline chloride (6-60mg/kg), given by i.p. injection immediately after training, dose-dependently enhanced retention in an inhibitory avoidance task. Combinations of low doses of glucose (10mg/kg) and choline chloride (20mg/kg) which alone were submaximally effective significantly increased retention latencies in a synergistic manner, an effect which was sensitive to atropine (0.5mg/kg). This beneficial effect vanished when higher doses of glucose or…
TREATMENT WITH SILDENAFIL PREVENTS IMPAIRMENT OF LEARNING IN RATS BORN TO PRE-ECLAMPTIC MOTHERS
2010
Pre-eclampsia is an important hypertensive pregnancy disorder and a main cause of maternal and fetal morbidity and mortality Children born from mothers with preeclampsia may present cognitive deficits The mechanisms leading to this cognitive impairment remain unclear and no treatments to improve it have been tested Pre-eclampsia is associated with impaired regulation of the nitric oxide 3 5 guanosine monophosphate cyclic (cGMP) pathway, which modulates some cognitive functions We hypothesized that alterations in the NO-cGMP pathway would be involved in the mechanisms leading to cognitive impairment in rats born to pre-eclamptic mothers and that treatment with sildenafil an inhibitor of the …
Perinatal high-fat diet increases hippocampal vulnerability to the adverse effects of subsequent high-fat feeding
2015
Epidemiological observations report an increase in fat consumption associated with low intake of n-3 relative to n-6 polyunsaturated fatty acids (PUFAs) in women of childbearing age. However, the impact of these maternal feeding habits on cognitive function in the offspring is unknown. This study aims to investigate the impact of early exposure to a high-fat diet (HFD) with an unbalanced n-6/n-3 PUFAs ratio on hippocampal function in adult rats. Furthermore, we explored the effects of perinatal HFD combined with exposure to HFD after weaning. Dams were fed a control diet (C, 12% of energy from lipids, n-6/n-3 PUFAs ratio: 5) or HFD (HF, 39% of energy from lipids, n-6/n-3 PUFAs ratio: 39) th…
Advanced technologies for detecting tremor in Parkinson's disease.
2019
Objective Accurate and reliable detection of tremor onset in Parkinson’s disease (PD) is critical to the success of adaptive deep brain stimulation (aDBS) therapy. Here, we investigated the potential use of feature engineering and machine learning methods for more accurate detection of rest tremor in PD. Methods We analyzed the local field potential (LFP) recordings from the subthalamic nucleus region in 12 patients with PD (16 recordings). To explore the optimal biomarkers and the best performing classifier, the performance of state-of-the-art machine learning (ML) algorithms and various features of the subthalamic LFPs were compared. We further used a Kalman filtering technique in feature…
The role of PET radiomic features in prostate cancer: a systematic review
2021
Aim: This systematic review aims to present the available evidence on the use of radiomic features (RFs) extracted from PET imaging in patients with prostate cancer (PCa). Materials and methods: A comprehensive literature search of studies on the utility of PET-derived RFs in patients with PCa was performed in the PubMed/MEDLINE database through February 24th, 2021 using the following search string: [“positron-emission tomography” (MeSh terms) OR “positron emission tomography computed tomography” (MeSh terms) OR “positron-emission tomography” (all fields) OR “positron emission tomography computed tomography” (all fields) OR “PET” (all fields)] AND [“radiomics” (all fields) OR “radiomic” (al…
Water maze performance, exploratory activity, inhibitory avoidance and hippocampal plasticity in aged superior and inferior learners
2002
In 28- to 30-month-old rats, in vitro short-term and long-term potentiation (STP and LTP) were measured in area CA1 of the hippocampus in seven superior and seven inferior learners, that were selected from a pool of 40 rats based on water maze escape performance over a period of 9 days. The aim was to examine whether levels of STP and LTP could account for group differences in learning of water maze escape, spatial preference and wall (thigmotaxis)-avoidance and in short-term retention of an inhibitory avoidance task. There was no significant group difference in open-field exploration, i.e. the number of rearings. In contrast to expectation, the superior and inferior learners did not differ…
The Lègami/Legàmi Service—An Experience of Psychological Intervention in Maternal and Child Care during COVID-19
2021
This study provides a descriptive analysis of the Lègami/Legàmi service, a free psychological support service in maternal and childcare, offered through the internet and by telephone that was initiated by the Italian Society of Pediatric Psychology (S.I.P.Ped.) during the COVID-19 medical emergency as an act of solidarity, first independently, and then in collaboration with the Italian Ministry of Health. This paper presents findings related to the “universe” of people who called the toll-free service, from the sociocultural characteristics of the users to the information collected by the professionals during the psychological pathways until human satisfaction was achieved. We provide a ret…
Always pay attention to which model of motor learning you are using
2022
This critical review considers the epistemological and historical background of the theoretical construct of motor learning for a more differentiated understanding. More than simply reflecting critically on the models that are used to solve problems—whether they are applied in therapy, physical education, or training practice—this review seeks to respond constructively to the recent discussion caused by the replication crisis in life sciences. To this end, an in-depth review of contemporary motor learning approaches is provided, with a pragmatism-oriented clarification of the researcher’s intentions on fundamentals (what?), subjects (for whom?), time intervals (when?), and purpose (for what…
Assessment of microalgae species, biomass, and distribution from spectral images using a convolution neural network
2022
AbstractEffective monitoring of microalgae growth is crucial for environmental observation, while the applications of this monitoring could also be expanded to commercial and research-focused microalgae cultivation. Currently, the distinctive optical properties of different microalgae groups are targeted for monitoring. Since different microalgae can grow together, their spectral signals are mixed with ambient properties, making estimations of species biomasses a challenging task. In this study, we cultured five different microalgae and monitored their growth with a mobile spectral imager in three separate experiments. We trained and validated a one-dimensional convolution neural network by…
Classification of Targets Using Statistical Features from Range FFT of mmWave FMCW Radars
2021
Radars with mmWave frequency modulated continuous wave (FMCW) technology accurately estimate the range and velocity of targets in their field of view (FoV). The targeted angle of arrival (AoA) estimation can be improved by increasing receiving antennas or by using multiple-input multiple-output (MIMO). However, obtaining target features such as target type remains challenging. In this paper, we present a novel target classification method based on machine learning and features extracted from a range fast Fourier transform (FFT) profile by using mmWave FMCW radars operating in the frequency range of 77–81 GHz. The measurements are carried out in a variety of realistic situations, including p…