Search results for "e learning"
showing 10 items of 2703 documents
Enhanced habit-based learning and decreased neurogenesis in the adult hippocampus in a murine model of chronic social stress
2009
Abstract Stress can induce preferential engagement of habit learning mediated by the basal ganglia, relative to learning that involves complex spatial associations contributed by the hippocampal formation. We explored in mice the influence that chronic episodes of social stress exert on the selection of cognitive/spatial vs. habit-based learning strategies. Male mice were exposed to repeated episodes of social confrontation and were categorized as dominant, subordinate or undetermined according to quantitative ethologically relevant parameters of aggression. Mice were then trained in a conditional discrimination task in the T-maze in the presence of allocentric cues until five correct choic…
Cognitive and behavioural effects induced by social stress plus MDMA administration in mice
2017
Adverse life experiences such as social stress may make an individual more vulnerable to drug addiction and mental disorders associated with drug consumption. The present work aimed to evaluate the effects of stress induced by acute social defeat combined with the administration of 3,4-methylenedioxymethamphetamine (MDMA) on depression-like behaviour, memory function and motor response to drug in late adolescent male mice. Two groups of mice were exposed to social defeat (SD) during four encounters with an aggressive co-specific, which took place on alternate days. Immediately after defeat, animals were treated with saline or MDMA 10mg/kg (SD+SAL and SD+MDMA). In control groups, mice were p…
Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and…
2009
Neurogenesis in the adult dentate gyrus (DG) of the hippocampus has been implicated in neural plasticity and cognition but the specific functions contributed by adult-born neurons remain controversial. Here, we have explored the relationship between adult hippocampal neurogenesis and memory function using tasks which specifically require the participation of the DG. In two separate experiments several groups of rats were exposed to fractionated ionizing radiation (two sessions of 7 Gy each on consecutive days) applied either to the whole brain or focally, aiming at a region overlying the hippocampus. The immunocytochemical assays showed that the radiation significantly reduced the expressio…
Improving Pattern Recognition Based Pharmacological Drug Selection Through ROC Analysis
2004
The design of new medical drugs is a very complex process in which combinatorial chemistry techniques are used. The goal consists of discriminating between molecular compounds exhibiting or not certain pharmacological activities. Different machine learning approaches have been recently applied to different drug design problems leading to competitive results in pointing at particular compounds with high probability of exhibiting activity. The present work first deeps into the natural trade-off between accuracy in the much less populated active group and false alarm rate which could lead to too many expensive laboratory tests. Preliminary results show how different classification techniques a…
Inferring slowly-changing dynamic gene-regulatory networks
2015
Dynamic gene-regulatory networks are complex since the interaction patterns between their components mean that it is impossible to study parts of the network in separation. This holistic character of gene-regulatory networks poses a real challenge to any type of modelling. Graphical models are a class of models that connect the network with a conditional independence relationships between random variables. By interpreting these random variables as gene activities and the conditional independence relationships as functional non-relatedness, graphical models have been used to describe gene-regulatory networks. Whereas the literature has been focused on static networks, most time-course experi…
Temporal difference method for processing dynamic speckle patterns
2010
A temporal difference method for processing dynamic speckle images is proposed. In the method two speckle images of an object, separated by a time interval, are subtracted one from the other to detect whether the speckle structure has changed or not. The rationale of the method is discussed. A variant of the method that allows measuring the area of an activity zone surrounded by a static region is tested in digital simulations. As a demonstrative experiment, that variant is employed to characterize the drying of a damp patch in filter paper.
Situated Language Learning Methods: a cross-sectional study on General Teaching and Language teaching
2018
Language teaching bases its theoretical and methodological framework on an axiom: object and teaching tool coincide in the target language. There follows that active learning is the key to efficacious linguistic knowledge as well as to transferable learning from a specific disciplinary context to a general one. This perspective is in tune with the educational claims and the learning aims fixed by the EAS teaching model, according to which learning is mediated by action and by the learner’s ability to simulate real life situations within classroom The present study means to start up an epistemological reflection moving from the comparison between language teaching and general teaching with r…
7th International Conference on Higher Education Advances (HEAd'21)
2021
Information and communication technologies together with new teaching paradigms are reshaping the learning environment.The International Conference on Higher Education Advances (HEAd) aims to become a forum for researchers and practitioners to exchange ideas, experiences,opinions and research results relating to the preparation of students and the organization of educational systems.
Writing tasks in EFL teaching : analysis of the writing tasks in Finnish schoolbooks
2015
Perusopetuksen opetussuunnitelman perusteet (2004) englannin kielen kirjoitustaidon osalta jättävät vastuun kirjoitustehtävien suunnittelusta opettajille ja kirjantekijöille. Oppimateriaaleja tutkimalla voidaan saavuttaa tietoa englannin kielen opetuksesta Suomessa. Tutkielma pyrkii selvittämään, minkä tyyppistä kirjoitustaitoa opetetaan suomalaisissa englannin kielen oppimateriaaleissa ja tutkimus keskittyy kirjoitustehtävien painopisteiden tutkimiseen kahden kysymyksen kautta. Ensiksi tutkittiin kirjoitustehtävien sijoittumista muotoa painottavien ja sisältöä painottavien tehtävien väliselle akselille, ja toiseksi selvitettiin, minkälaisia kirjoittamisen taitoja tehtävät harjoittavat. Ain…
Exploring relationships between effort, motion, and sound in new musical instruments
2020
We investigated how the action–sound relationships found in electric guitar performance can be used in the design of new instruments. Thirty-one trained guitarists performed a set of basic sound-producing actions (impulsive, sustained, and iterative) and free improvisations on an electric guitar. We performed a statistical analysis of the muscle activation data (EMG) and audio recordings from the experiment. Then we trained a long short-term memory network with nine different configurations to map EMG signal to sound. We found that the preliminary models were able to predict audio energy features of free improvisations on the guitar, based on the dataset of raw EMG from the basic soundprodu…