Search results for "edge"

showing 10 items of 3866 documents

Costruzione della Sicilian Experience. Il caso di Anna Tasca Lanza Cooking School

2020

La Sicilia è storicamente oggetto di narrative di stampo marcatamente edonistico, anche di recente casi rispecchiate e alimentate da casi editoriali di grande successo. Con l’imporsi di nuovi trend turistici improntati alla scoperta di specialità gastronomiche e vinicole locali, il settore turistico dell'isola gode di un ciclo particolarmente positivo. Le strutture di produzione e distribuzione agroalimentare e le realtà ricettive del territorio si stanno evolvendo per assecondare questo nuovo tipo di domanda, con effetti prevedibili di patrimonializzazione e ricostruzione semiotica della cultura alimentare tipica. Tra le realtà più in vista, nel settore, c’è la scuola di cucina Anna Tasca …

cibo semiotica semiotica del gusto Sicilia turismo patrimonio intangibile saperi taciti patrimonializzazionefood semiotics authenticity tourism Sicily intangible heritage embodied knowledge food heritageSettore M-FIL/05 - Filosofia E Teoria Dei Linguaggi
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The hedgehog receptor patched is involved in cholesterol transport.

2011

International audience; BACKGROUND: Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors, and one of the most affected Shh signaling steps found in these tumors is the regulation of the signaling receptor Smoothened by the Shh receptor Patched. In the present work, we investigated Patched activity and the mechanism by which Patched inhibits Smoothened. METHODOLOGY/PRINCIPAL FINDINGS: Using the well-known Shh-responding cell line of mouse fibroblasts NIH 3T3, we first observed that enhancement …

ciliumlcsh:MedicineyeastBiochemistryReceptors G-Protein-CoupledTransmembrane Transport ProteinsMicechemistry.chemical_compound0302 clinical medicineMolecular Cell Biology[SDV.IDA]Life Sciences [q-bio]/Food engineeringMembrane Receptor SignalingBiomacromolecule-Ligand InteractionsSonic hedgehoglcsh:ScienceComputingMilieux_MISCELLANEOUS0303 health sciencesMultidisciplinaryMechanisms of Signal TransductionVeratrum Alkaloids[SDV.IDA] Life Sciences [q-bio]/Food engineeringdrosophilaSmoothened ReceptorLipidsHedgehog signaling pathwayCell biologySterolsSmoothened ReceptorAlimentation et Nutritionembryonic structurescilMembranes and Sorting[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Signal transductionvesicular traffickingSignal TransductionResearch Articleprimary ciliumPatched ReceptorsPatchedsignal-transductionanimal structuresCyclopamine[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process EngineeringBiophysicsReceptors Cell Surfacepathway activationSaccharomyces cerevisiaetransduction du signalBiology03 medical and health sciencessonic hedgehoglipidAnimalsHumansFood and NutritionHedgehog Proteins[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringBiology030304 developmental biologyPatched Receptorsprotein signalsCell Membranelcsh:RProteinscholesterolBiological TransportTransmembrane Proteinssterol-sensing domainchemistry[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]NIH 3T3 Cellscholesterol;lipid;cell trafficking; yeast;drosophila;cells ; pathway activation; vesicular trafficking; signal-transduction; sonic hedgehog;sterol-sensing domain; primary cilium;protein signalsbiology.proteincellslcsh:Qcell traffickingSmoothened030217 neurology & neurosurgery
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Impact of the knowledge society in the university and in scientific communication

2014

Over the last two decades, as a result of the introduction and intensive use of technologies for information and general knowledge, especially from the internet, the university is living in a process of complete transformation that affects it´s academic and organizational structures as well as the conception of educational methodology. The ICTs have demonstrated a need to establish coherent institutional strategies in their use and application, along with the possibility to expand the sphere of institutional action, in regards to general access to higher education. All of this shows an existing change from a model of education based on the transmission of knowledge, that was rather limited …

ciència obertaEducación superior; sociedad del conocimiento; e-learning; acceso abierto; ciencia abierta; altmetricaltmetriceducación superiorsocietat del coneixementWeb-based instructionEnseñanza virtualopen sciencePedagogy; education; Communicatione-learningciencia abiertaopen accesseducationPedagogyCommunicationpedagogía; educación; comunicacióneducació superiorcomunicaciónaccés obertknowledge societyacceso abiertoaltmetricsEnsenyament virtualsociedad del conocimientohigher educationpedagogíaeducación
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Alternatives to the present global development pattern : ecovillages – a model for sustainable living?

2016

Master thesis development management - University of Agder 2016 The current way of development is exhausting the planets limitations, the continues increase in consumption are degrading the nature that is relied on for human existence. Thus, it is necessary to define an alternative way of developing. The aim is to achieve happiness for all, sustaining the resources of the planet. Ecovillages are recognized as a sustainable alternative which encompasses a holistic approach to the term sustainability. Through qualitative research in the form of participatory observations, interviews and a survey performed in Gambhira, an ecovillage in rural Colombia, the sustainability, educational mission as…

climate changeUT503VDP::Social science: 200::Social anthropology: 250ecovillagesconsumerismPachamamaecologysustainabilityglobal warmingecosystemsenvironmentancestral knowledge
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Basal ice formation in snow cover in Northern Finland between 1948 and 2016

2018

Abstract Basal ice formation in the terrestrial snow cover is a common phenomenon in northern circumpolar areas, one having significant impacts on ecosystems, vegetation, animals and human activities. There is limited knowledge on the spatial and temporal occurrence of basal ice formation because of the sparse observation network and challenges involved in detecting formation events. We present a unique dataset on the annual extent of ice formation events in northern Finland between 1948 and 2016 based on reindeer herders’ descriptions of the cold season in their management reports. In extreme years, basal ice can form over wide geographical extents. In approximately half of the herding dis…

climate changeporotpractitioners’ knowledgejääFennoskandiasnow coverwarm winter eventsilmastonmuutoksetsemi-domesticated reindeer (Rangifer tarandus tarandus)human activitiesbasal icelumipeiteNorthern Fennoscandia
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Embodied graffiti and street art research

2021

Graffiti and street art research (GSAR) has become more acknowledged within the academic discourse; however, it has much to gain from theorising its methodological aspects. As a multidisciplinary field, GSAR has mostly used qualitative research methods, exploring urban space through methods that range from visual recordings to ethnography, emphasising the researchers’ reflexivity. This qualitative approach has, however, paid little attention to the role of embodied practices. In this paper we discuss how embodied methodologies provide multisensory research results where the experienced moments, the participant’s and researcher’s senses, cognition and mobility in urban spaces are connected.…

cognitionkognitioethnographysukupuoliwalkingHistory and Philosophy of ScienceHistory and philosophy of scienceMultidisciplinary approachGSAREthnographyedgeworkgenderkatutaidegraffititsensesSociologyvisuaalinen kulttuuriembodied methodologyetnografia050901 criminology05 social sciencesaistitkaupunkiympäristöGraffitistreet artgraffiti5142 Social policy050903 gender studiesEmbodied cognitionAesthetics0509 other social scienceskaupunkitilaSocial Sciences (miscellaneous)
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Muusikon tietämisen tavat : moniälykkyys, hiljainen tieto ja musiikin esittämisen taito korkeakoulun instrumenttituntien näkökulmasta

2011

cognitionkognitiohiljainen tietoopetustaitomusicianshipmuusikotmusiikkikasvatusinstrumental teachingtietoteoriaepistemologytacit knowledgemusic educationintelligence
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On a journey towards web literacy : the electronic learning space Netro

2004

collaborative knowledge buildingmedia literacyteaching materialsmultiliteraciesweb literacyon-line learningsocio-constructivismelectronic learning spacemethods and approachese-learning
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Contextualizing AMO explanations of knowledge sharing in MNEs: the role of organizational and national culture

2022

AbstractAbility, motivation, and opportunity (AMO) approaches have dominated studies of knowledge sharing in multinational enterprises (MNEs). We argue that there is a need to consider both the national and organizational cultural contexts. Beyond their direct influence on knowledge sharing with colleagues in other business units (BUs), national and organizational culture significantly reinforce the positive relation between individual motivation and knowledge sharing. Thus, our multi-level approach to knowledge sharing in MNEs gives rise to a contextualized AMO approach that provides a novel and more potent understanding of variations in knowledge sharing. At the individual level, our appr…

collaborative organizational cultureStrategy and Managementcollaborative national cultureUNESCO::CIENCIAS ECONÓMICASBusiness and International Managementcontextualized AMOknowledge sharingintrinsic motivationmulti-level
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Zebrafish Fins as a Model System for Skeletal Human Studies

2007

Recent studies on the morphogenesis of the fins ofDanio rerio(zebrafish) during development and regeneration suggest that a number of inductive signals involved in the process are similar to some of those that affect bone and cartilage differentiation in mammals and humans. Akimenko et al. (2002) has shown that bone morphogenetic protein-2b (BMP2b) is involved in the induction of dermal bone differentiation during fin regeneration. Many other groups have also shown that molecules from the transforming growth factor-beta superfamily (TGFβ), including BMP2, are effective in promoting chondrogenesis and osteogenesisin vivoin higher vertebrates, including humans. In the present study, we review…

collagenPathologylcsh:MedicineReview Articlebonelcsh:TechnologydentineExtracellular matrixbone regenerationOsteogenesisMorphogenesislcsh:ScienceZebrafishZebrafishGeneral Environmental Sciencetransforming growth factor betaDermal bonebiologyenamelGeneral MedicineCell biologyendochondral ossificationmedicine.anatomical_structureModels Animalmedicine.medical_specialtyextracellular matrixosteocyteregenerative medicineray dermal boneBone morphogenetic protein 2Bone and BonesGeneral Biochemistry Genetics and Molecular BiologyFin regenerationsonic hedgehogbone morphogenetic proteinsmedicineAnimalsHumansactinopterygian fishesmammalslepidotrichiascleroblastmesenchymal stem cellslcsh:TRegeneration (biology)Cartilagelcsh:RZebrafish Proteinsbone repairbiology.organism_classificationChondrogenesisCartilageregenerationintramembranous ossificationlcsh:Qcell therapyvertebratesThe Scientific World Journal
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