Search results for "edge"

The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu

2014

Sonic Hedgehog (SHH)-GLI signalling plays an important role during embryogenesis and in tumorigenesis. The survival and growth of several types of cancer depend on autonomously activated SHH-GLI signalling. A protein complex containing the ubiquitin-ligase MID1 and protein phosphatase 2A (PP2A) regulates the nuclear localization and transcriptional activity of GLI3, a transcriptional effector molecule of SHH, in cancer cell lines with autonomously activated SHH signalling. However, the exact molecular mechanisms that mediate the interaction between MID1 and GLI3 remained unknown. Here, we show that MID1 catalyses the ubiquitination and proteasomal cleavage of the GLI3-regulator Fu. Our data…

Exploring students’ metacognition in relation to an integral-area evaluation task

2021

Several studies have been conducted to explore students’ understanding of the integral-area relationships, however, only a few focused on students’ metacognition in relation to this topic. In this study, students’ metacognitive knowledge, skills, and experiences in relation to an integral-area evaluation task are explored using semi-structured interviews and think-aloud protocol. The results show that several students developed monitoring strategies in relation to integral-area relationships; however, they do not use these strategies when solving integral-area tasks. The findings suggest that teachers and lecturers could use monitoring strategies more often when solving mathematical questio…

Beliefs about learning English as a foreign language : comparisons of two groups of Finnish university students

2002

Beliefs about second language acquisition held by dysphatic students

2006

Framework for pedagogical learning analytics

2018

Learning analytics is an emergent technological practice and a multidisciplinary scientific discipline, which goal is to facilitate effective learning and knowledge of learning. In this design science research, I combine knowledge discovery process, a concept of pedagogical knowledge, ethics of learning analytics and microservice architecture. The result is a framework for pedagogical learning analytics. The framework is applied and evaluated in the context of agency analytics. The framework contributes to the practical use of learning analytics.

Zināšanu pārbaudes testi izmantošanai viedierīcēs

2018

Diplomdarbā aprakstītā pētījuma mērķis izpētīt mobilo testu izmantošanas aktualitāti un pielietošanas iespējas, lai veicinātu to izmantošanu pedagoģiskajā procesā. Pētījumam izmantoto datu ieguves kvalitatīvās metodes ir intervijas un platformu analīze, kvantitatīvā - pedagogu aptauja. Interviju respondenti ir sākumskolas, vidusskolas un augstskolas pedagogi, kā arī Uzdevumi.lv direktors Edgars Škutāns. Tika vadīts seminārs, iepazīstinot profesionālās vidusskolas Mediju mākslas nodaļas pedagogus ar zināšanu pārbaudes testu platformu QUIZIZZ, pēc kura tika veikta pedagogu aptauja. Pētījumā noskaidrots, ka viedierīcērs izmantojamo zināšanu pārbaudes testu galvenās priekšrocības ir automātiska…

Schede per il censimento degli alberi monumentali di Sicilia. 27-36

2010

Conceptualizing nature-based science tourism: a case study of Seili Island, Finland

2021

Nature-based tourism has been widely addressed, yet research on nature-based science tourism, founded on science, scientific knowledge, and/or engagement in scientific research, is still scarce. Drawing on tourist motivation, nature-based tourism, special interest tourism, and science tourism, a novel theoretical conceptualization of nature-based science tourism was developed. The framework identified three categories of science tourism with intensifying levels of tourists’ interest in scientific knowledge and tourist engagement: tourism based on scientific knowledge, tourism with scientific adventure or volunteering, and scientific research tourism. In the empirical part, the framework was…

Conocimiento, traza e ingenio en la arquitectura valenciana del siglo XV

2012

In the last decades historiography of gothic architecture in the Crown of Aragon has focused on buildings monographs, documentary research and technical change in stone building. On the other hand, historians of technology have given special attention to the issue of innovation and its diffusion in the late Middle Ages, considering building techniques as a particular field of research. This essay studies transmission of technical knowledge in building trades in order to explain architectural changes in an outstanding environment of innovation such as the kingdom of Valencia in the 14th and 15th centuries, especially from 1430 onwards. Having account of previous research and some cases of st…

Sustainability Development in Mathematics Education : A Case Study of What Kind of Meanings Do Prospective Class Teachers Find for the Mathematical S…

2019

In this article, our focus is on sustainable development in mathematics education from the point of view of teacher training. The aim was to develop prospective teachers’ content knowledge and pedagogical content knowledge of school mathematics. As a case study, we chose the mathematical symbol “a/b”, and examined how prospective class teachers in Finland connect it to the concepts of fraction, ratio, division, rational number or probability. Mathematics textbooks often have a central role in lessons, and they affect strongly how pupils understand concepts and the relationships between them. We chose languaging as a multi-semiotic approach to interpreting what kind of meanings the prospecti…