Search results for "effective"
showing 10 items of 1371 documents
La prohibición de la tortura: Condenas del TEDH al estado español por la violación del artículo 3 del CEDH en su vertiente procesal
2018
The European Court of Human Rights (ECtHR) has recently condemned the Spanish State for an infringement of the third article of the European Convention of Human Rights. As a result, the number of condemns to the Spanish State have increased to ten due to violation of the procedural limb of the mentioned article. In other words, because of the non-effective investigation of possible torture cases. The main objective of this paper is to expose the cases and the doctrine that ECtHR has established around this obligation derived from the prohibition of the torture.
Experimental Evidence for an Attractive p-φ Interaction
2021
Physical review letters 127(17), 172301 (2021). doi:10.1103/PhysRevLett.127.172301
Análisis coste-utilidad de la triple terapia con telaprevir en pacientes con hepatitis C no tratados previamente
2014
Introducción: En España, con una prevalencia del 2,5%, la hepatitis C (VHC) se asocia a una elevada morbi-mortalidad. El tratamiento combinado de telaprevir y peginterferon/ribavirina ([T/PR]) es eficaz en pacientes con VHC-G1. El objetivo primario de este estudio fue evaluar la relación coste-utilidad (RCUI) de [T/PR] versus peginterferon alfa 2a/ribavirina ([PR]) en pacientes naïve VHC-G1, según el grado de fibrosis y bajo la perspectiva del sistema sanitario español. Metodología: La eficacia y la incidencia de efectos adversos (EAs) se obtuvieron de los estudios ADVANCE y OPTIMIZE. La estimación de los costes de monitorización, de manejo de EAs y de la enfermedad por estados de salud (€,…
Occupational Safety and Health
2012
Abstract Occupational health and safety reflects the effect of the work environment on employees, groups and work units in organizations, and organizations as a whole. This chapter provides an overview of the research on workplace safety and specifically discusses safety training, regulatory focus, safety climate, leadership, and job design as they relate to safety. Additionally, the literature on occupational health, drawing heavily on the occupational stress literature, discusses the employee-employer relationship from a psychological contract perspective, including climate for sexual harassment, collective burnout and its contagion, recovery, and organizational wellness programs. Particu…
Gaia -ESO Survey: Analysis of pre-main sequence stellar spectra
2015
This paper describes the analysis of UVES and GIRAFFE spectra acquired by the Gaia-ESO Public Spectroscopic Survey in the fields of young clusters whose population includes pre-main sequence (PMS) stars. Both methods that have been extensively used in the past and new ones developed in the contest of the Gaia-ESO survey enterprise are available and used. The internal precision of these quantities is estimated by inter-comparing the results obtained by such different methods, while the accuracy is estimated by comparison with independent external data, like effective temperature and surface gravity derived from angular diameter measurements, on a sample of benchmarks stars. Specific strategi…
Generalized effective stress concept for saturated active clays
2021
Experimental evidence shows that changes in pore-water chemistry can significantly affect the mechanical behavior of saturated active clays. Despite this evidence, how the chemical composition of the pore water can be considered in effective stress definition is questionable. This paper develops the concept of generalized effective stress for active clays. To this end, physicochemical studies on water–clay mineral interactions are used to clearly define the different types of ions and water present in an active clay. In particular, the presence of both movable and non-movable ions within the liquid water is highlighted. Taking this into account, thermodynamic and geochemistry principles ar…
Economic evaluation of azoles as primary prophylaxis for the prevention of invasive fungal infections in Spanish patients undergoing allogeneic haema…
2016
Patients undergoing allogeneic haematopoietic stem cell transplantation (alloHSCT) are at risk of developing invasive fungal infections (IFIs). Even with introduction of oral triazole antifungal agents (fluconazole, itraconazole, posaconazole and voriconazole) IFI-associated morbidity and mortality rates and economic burden remain high. Despite their proven efficacy, it is currently unknown which is the most cost-effective antifungal prophylaxis (AFP) agent. To determine the costs and outcomes associated with AFP, a decision-analytic model was used to simulate treatment in a hypothetical cohort of 1000 patients undergoing alloHSCT from the perspective of the Spanish National Health System. …
Clinical applicability and cost-effectiveness of DIABSCORE in screening for type 2 diabetes in primary care
2017
Aims: To evaluate the applicability and cost-effectiveness of a clinical risk score (DIABSCORE) to screen for type 2 diabetes in primary care patients. Methods: Multicenter cross-sectional study of 10,508 adult no previously diagnosed with diabetes, in 2 Spanish regions (Canary Islands and Valencian Community). The variables comprising DIABSCORE were age, waist to height ratio, family history of diabetes and gestational diabetes. ROC curves were obtained; the diabetes prevalences odds ratios (HbA1c >= 6.5%) between patients exposed and not exposed to DIABSCORE >= 100, and to fasting blood glucose >= 126 mg/dL were calculated. The opinions of both the professionals and the patients concernin…
Cost analysis of recall strategies for non-invasive diagnosis of small hepatocellular carcinoma.
2010
Abstract Background Which is the least expensive recall policy for nodules in the cirrhotic liver remains unclear. Aim Aim of the study was to analyze the costs of different recall diagnostic strategies of hepatocellular carcinoma (HCC) on cirrhosis on a real series of patients. Methods 75 consecutive small liver nodules (10–30 mm) detected at conventional ultrasonography in 60 patients with cirrhosis were submitted to contrast-enhanced ultrasound, computed tomography and gadolinium-magnetic resonance imaging with a final diagnosis established according to the latest guidelines which include different strategies for nodules 10–19 mm or ≥20 mm. The actual costs required to fully characterise…
Does Endovascular Treatment with Curative Intention Have Benefits for Treating High-Grade Arteriovenous Malformation versus Radiosurgery? Efficacy, S…
2021
Background The treatment of high-grade arteriovenous malformations (AVMs) remains challenging. Microsurgery provides a rapid and complete occlusion compared with other options but is associated with undesirable morbidity and mortality. The aim of this study was to compare the occlusion rates, incidence of unfavorable outcomes, and cost-effectiveness of embolization and stereotactic radiosurgery (SRS) as a curative treatment for high-grade AVMs. Methods A retrospective series of 57 consecutive patients with high-grade AVM treated with embolization or SRS, with the aim of achieving complete occlusion, was analyzed. Demographic, clinical, and angioarchitectonic variables were collected. Both t…