Search results for "effectivene"

showing 10 items of 373 documents

Cost effectiveness of boceprevir or telaprevir for previously treated patients with genotype 1 chronic hepatitis C.

2013

Background & Aims Randomised controlled trials (RCTs) show that triple therapy (TT) with peginterferon alfa, ribavirin, and boceprevir (BOC) or telaprevir (TVR) is more effective than peginterferon-ribavirin dual therapy (DT) in the treatment of genotype 1 (G1) chronic hepatitis C (CHC) patients with previous relapse (RR), partial response (PAR), and null-response (NR). We assess the cost-effectiveness of TT compared to no therapy in the treatment of patients previously treated with G1 CHC. Methods The available published literature provided the data source. The target population was made up of previously treated Caucasian patients with G1 CHC and these were evaluated over a lifetime horizo…

MaleTVRCost effectivenessCost-Benefit AnalysisPIPeginterferon-alfaBOCHepacivirusBOC Boceprevir CHC Cost-effectiveness DT G1 ICER NR PAR PI PegIFN RBV RR TVR Telaprevir boceprevir chronic hepatitis C dual therapy genotype 1 incremental cost-effectiveness ratio non-response partial response pegylated interferon protease inhibitors relapse ribavirin telaprevirTelaprevirTelaprevirchemistry.chemical_compoundPegylated interferonnon-responseboceprevirincremental cost-effectiveness ratioRBVTreatment FailureDThealth care economics and organizationsRandomized Controlled Trials as Topicrelapsecost effectivenessICERMiddle AgedMarkov ChainsModels EconomicItalyQuality-Adjusted Life YearsSettore SECS-P/02 - politica economicaSettore SECS-S/01 - StatisticaIncremental cost-effectiveness ratioOligopeptidesmedicine.drugmedicine.medical_specialtyGenotypeProlineribavirinSettore MED/12 - GASTROENTEROLOGIAprotease inhibitorsNRRRAntiviral AgentsInternal medicineBoceprevirG1medicineHumanschronic hepatitis Cpegylated interferongenotype 1Hepatologybusiness.industryRibavirindual therapyHepatitis C ChronicQuality-adjusted life yearSurgeryCHCPegIFNchemistryCost-effectivenesspartial responsebusinessPAR
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Safety and effectiveness of intravenous morphine for episodic breakthrough pain in patients receiving transdermal buprenorphine.

2006

Supplemental dosing of an opioid is the main treatment suggested to manage breakthrough pain in cancer patients. The intravenous route has been proven to be safe and effective, providing rapid analgesia in patients receiving oral morphine. Transdermal buprenorphine (TTS-BUP) is increasingly used in cancer pain management, but this drug has been labeled as a difficult drug to use in combination with other opioids. The aim of this open-label study was to verify the safety and effectiveness of intravenous morphine (IV-MO) for the treatment of episodic pain in cancer patients receiving TTS-BUP. A consecutive sample of 29 cancer patients, who were treated with TTS-BUP, reported an acceptable bas…

Malecancer painPalliative careExacerbationtransdermal buprenorphinePainOpioidAdministration CutaneousInjectionsNeoplasmsmedicineSecondary PreventionHumansepisodic breakthrough painDosingAdverse effectbreakthrough pain; cancer pain; Intravenous morphine; opioids; transdermal buprenorphine; Administration Cutaneous; Analgesics Opioid; Buprenorphine; Drug Combinations; Female; Humans; Injections Intravenous; Male; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement; Palliative Care; Secondary Prevention; Treatment Outcome; Anesthesiology and Pain Medicine; Neurology (clinical); Neurology; Nursing (all)2901 Nursing (miscellaneous)Nursing (all)2901 Nursing (miscellaneous)General NursingPain MeasurementAnalgesicsMorphinebusiness.industryPalliative CareopioidsIntravenous morphineMiddle Agedbreakthrough painBuprenorphineAnalgesics Opioidtransdermal buprenorphine.Drug CombinationsCutaneousAnesthesiology and Pain MedicineTreatment OutcomeNeurologyOpioidAnesthesiaAdministrationInjections IntravenousMorphineFemaleNeurology (clinical)IntravenousCancer painbusinesssafety and effectiveness of intravenous morphinemedicine.drugBuprenorphineJournal of pain and symptom management
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Effectiveness and Estimation of Cost-Effectiveness of a Group-Based Multicomponent Physical Exercise Programme on Risk of Falling and Frailty in Comm…

2019

This study analyses the effectiveness and cost-effectiveness of a group-based multicomponent physical exercise programme aimed at reducing the risk of falling and frailty in community-dwelling older adults. This is a pretest&ndash

Malemedicine.medical_specialtyActivities of daily livingCost effectivenessCost-Benefit AnalysisHealth Toxicology and Mutagenesislcsh:MedicinePoison controlPhysical exercisefrailtySuicide preventionArticleOccupational safety and healthBody Mass Index03 medical and health sciences0302 clinical medicinephysical exerciseActivities of Daily LivingfallsInjury preventionHumansMedicine030212 general & internal medicineExercisePostural Balanceolder adultsAgedAged 80 and overbusiness.industrylcsh:RPublic Health Environmental and Occupational HealthExercise TherapySelf Carerisk of fallingageingPhysical therapyAccidental FallsFemaleIndependent Livingbusinesshuman activitiesBody mass index030217 neurology & neurosurgeryInternational Journal of Environmental Research and Public Health
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Different skin prick test sensitization patterns do not influence the response to omalizumab in severe asthma

2017

Malemedicine.medical_specialtySevere asthmaSevere asthmaImmunologyEffectivenessOmalizumabOmalizumabSettore MED/10 - Malattie Dell'Apparato RespiratorioSeverity of Illness IndexmedicineHumansImmunology and AllergyAnti-Asthmatic AgentsSensitizationRetrospective StudiesSkin Testsbusiness.industryEffectiveneReal-lifeImmunoglobulin EEffectiveness; Omalizumab; Pollen sensitized; Real-life; Severe asthma; Immunology and Allergy; ImmunologyDermatologyAsthmaPollen sensitizedTest (assessment)Respiratory Function Testsmedicine.anatomical_structureTreatment Outcomeeffectiveness; omalizumab; pollen sensitized; real-life; severe asthmaFemaleImmunizationbusinessmedicine.drug
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Efficacy and Cost-Effectiveness of Dabigatran Etexilate Versus Warfarin in Atrial Fibrillation in Different Age Subgroups

2014

This study aims to estimate the cost-effectiveness of dabigatran 150 mg twice daily versus warfarin for stroke and systemic embolism risk reduction in patients with nonvalvular atrial fibrillation initiating treatment before age 75 (<75), at or after age 75 (≥75), and the overall population (All) from a US Medicare payer perspective. Clinical event rates by age cohort with dabigatran or warfarin for safety-on-treatment and intent-to-treat populations were estimated from Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY). An economic model was adapted using these data to evaluate the impact of starting age on clinical and economic outcomes. Costs were obtained from Medicare p…

Malemedicine.medical_specialtyTime FactorsCost effectivenessCost-Benefit AnalysisMedicareAntithrombinsDrug Administration ScheduleDrug CostsDabigatranThromboembolismInternal medicineAtrial FibrillationmedicineHumansIn patientcardiovascular diseasesStrokeAgedbusiness.industryIncidenceFollow up studiesWarfarinSystemic embolismAtrial fibrillationPrognosismedicine.diseaseUnited StatesDabigatranbeta-AlanineCardiologyBenzimidazolesFemalebusinessCardiology and Cardiovascular MedicineFollow-Up Studiesmedicine.drugThe American Journal of Cardiology
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Moderate influenza vaccine effectiveness against A(H1N1)pdm09 virus, and low effectiveness against A(H3N2) subtype, 2018/19 season in Italy

2019

Background: Influenza vaccines are updated every year to match the vaccine strains with currently circulating viruses; consequently influenza vaccine effectiveness (IVE) has to be assessed annually.Research design and methods: A test-negative case-control study was conducted within the context of the Italian sentinel influenza surveillance network to estimate IVE by age group, virus subtype, and vaccine brand in medically attended laboratory-confirmed influenza.Results: In Italy, the 2018/19 influenza season was characterized by the co-circulation of influenza A(H1N1)pdm09 and A(H3N2) viruses. The adjusted IVE estimate in preventing influenza was moderate (44.8%, 95% CI: 18.8 to 62.5) again…

Maletest-negative case-control study0301 basic medicinePrevalenceInfluenza vaccine effectiveness test-negative case-control study national influenza surveillance network ItalySettore MED/42 - Igiene Generale E ApplicataInfluenza A Virus H1N1 Subtype0302 clinical medicineDrug DiscoveryEpidemiology030212 general & internal medicineChildInfluenza vaccine effectivenessAged 80 and overnational influenza surveillance networkAge Factorsvirus diseasesMiddle Aged3. Good healthVaccinationTreatment OutcomeItalyInfluenza VaccinesChild PreschoolMolecular MedicineFemaleInfluenza vaccine effectiveness; Italy; national influenza surveillance network; test-negative case-control studyAdultmedicine.medical_specialtyAdolescentInfluenza vaccineImmunologyContext (language use)VirusYoung Adult03 medical and health sciencesInternal medicineInfluenza HumanmedicineAnimalsHumansAgedPharmacologybusiness.industryInfluenza A Virus H3N2 SubtypeCase-control studyInfant030104 developmental biologyImmunizationCase-Control StudiesbusinessExpert Review of Vaccines
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Project driven orders managing practices in Polish construction industry

2014

Contemporary enterprises, focused on external business environment, define their strategic targets, with regard to the context of market and customer requirements. Their internal organization form should aim towards transformations, driven by global economic, political and social processes. This further involves rejecting of existing stereotypes, distribution of tasks and functions performance, as well as a possibility to adapt in response to environment variations, being well exemplified by project driven organizations. Management of individual single orders in enterprises with functional structures can be treated as “project driven orders” management. The orders may have manufacturing or …

Manager CompetenciesKnowledge ManagementEffectiveness of Project ManagementSMEsProject Driven OrderOrganizational Project Management MaturityUniversal Journal of Management
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The effectiveness of several market integration measures when facing a market turmoil

2003

Many market integration measures are operationalized to compute their numerical values during a period characterized by the lack of stability and market turmoil. The results of the tests give their degree of effectiveness, and reveal that the measures based on the principles of asset valuation, versus statistical measures, more clearly yield the level of integration of financial markets. Besides, cross market arbitrage-linked measures and equilibrium models-linked measures provide complementary information and reflect different properties, and consequently, both types of measures may be useful in practice.

Market integrationMathematical modelsOperationalizationFinancial economicsYield (finance)Financial marketCorrelation analysisEffectivenessMarket microstructureMarket depthSecurities marketsMarket analysisEconomicsFutures contractEmpresa
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Virtual and augmented reality: Advancing research in consumer marketing

2020

Abstract Virtual reality (VR) and augmented reality (AR) technologies are having a profound impact on a variety of marketing practices and are attracting increasing attention from marketing researchers. In this article, we review developments in VR/AR applications and research in the area of consumer marketing. We propose a conceptual framework for VR/AR research in consumer marketing that centers around consumer experiences provided by VR/AR applications along the customer journey and the effectiveness of such applications, and delve into the key concepts and components of the framework. Next, we provide a comprehensive overview of VR/AR applications in current practices and extant researc…

MarketingComputer science05 social sciencesVirtual realityVariety (cybernetics)Consumer experienceExtant taxonConceptual frameworkVirtual reality Augmented reality Consumer experience Customer journey VR/AR effectiveness0502 economics and businessKey (cryptography)050211 marketingAugmented realityMarketing050203 business & management
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Compensation and control sales policies, and sales performance: the field sales manager's points of view

2011

PurposeThe purpose of this paper is to analyse the relationship among the compensation system (fixed or commission) applied to salespeople, the system by which they are controlled, and the effects of both on individual performance and sales organization effectiveness. Previous research has been extended in a different country/context, and from the field sales manager's points of view.Design/methodology/approachFirst, a cluster analysis was used to obtain a set of groups of salespeople characterized by their main compensation system (salary and/or commission). Also, ANOVA is used to analyze the significance of the differences due to the different compensation system.FindingsThe empirical dat…

MarketingControl (management)Context (language use)SalaryCommissionBusinessBusiness and International ManagementSales managementMarketingSet (psychology)Organizational effectivenessCompensation (engineering)Journal of Business &amp; Industrial Marketing
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