Search results for "elderly."

Perspective: Protein Supplementation in Frail Older Persons: Often Necessary but Not Always Sufficient

2013

Lifetime Adherence to Physical Activity Recommendations and Fall Occurrence in Community-dwelling Older Adults: a Retrospective Cohort Study

2012

Wright RL, Robinson PD, Peters DM. Lifetime adherence to physical activity recommendations and fall occurrence in community-dwelling older adults: a retrospective cohort study. J. Hum. Sport Exerc. Vol. 7, No. 1, pp. 310-320, 2012. Falling is a major health concern for community-dwelling older adults. Regular physical activity has been proposed to prevent falls. The aim of this study was to assess whether the achievement of the 2004 UK Department of Health physical activity recommendations over a lifetime had a protective effect against falling in older people. 313 community-dwelling older adults completed a questionnaire about lifetime physical activity and fall occurrence. There were sign…

Regional Brain Volume, Brain Reserve and MMSE Performance in Healthy Aging From the NEUROAGE Cohort: Contributions of Sex, Education, and Depression …

2021

Objective: The aim of this study was twofold. First, to investigate the relationship between age, gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) volumes, brain reserve (BR), and specific regions of interest (ROIs) with global cognitive function in healthy older adults participating in a longitudinal study on aging in the island country of Cyprus. Second, to assess the contribution of important demographic and psychosocial factors on brain volume. Specifically, the effects of sex and years of education and the association between depression symptoms on brain volume were also explored in this Mediterranean cohort.Methods: Eighty-seven healthy older adults (males = 37, fema…

Centenarian Offspring as a Model of Successful Ageing

2019

The rapid increase in global average life expectancy, observed during the last years, due to improvements in sanitation and medical care, pushes the scientific community to understand the basis of the ageing process. In particular, in order to improve the life quality of elderly people, current ageing research is focused on the identification of biological mechanisms involved in successful ageing, a complex process influenced by several factors, including genetic, environment, and lifestyle. Centenarians, i.e., subjects who have reached ten or more decades of life, escaping the common age-related diseases, are the leading exponent of successful ageing. However, the rarity of such exponents,…

Demographic Differences in the Effectiveness of a Physical Activity Application to Promote Physical Activity: Study Among Aged People

2021

The global population is ageing and simultaneously the life expectancy at older ages is improving. To support healthy and active aging, it is imperative to find solutions to support physical activity (PA) in older age. Digital wellness technologies are a potential solution, but in order for such technologies to be successful, research is needed to gain a better understanding on their use and effectiveness among aged people. To address this need, this study investigated the effectiveness of a physical activity application to promote PA behavior among aged people of different demographics (gender, age, education, marital status). PA levels were measured before taking the application into use …

Understanding ageing: Biomedical and bioengineering approaches, the immunologic view

2008

Abstract During the past century, humans have gained more years of average life expectancy than in the last 10,000 years; we are now living in a rapidly ageing world. The sharp rise in life expectancy, coupled to a steady decline in birth rates in all developed countries, has led to an unprecedented demographic revolution characterized by an explosive growth in the number and proportion of older people. Ageing is a complex process that negatively impacts the development of the immune system and its ability to function. Progressive changes in the T and B cell systems over the life span have a major impact on the capacity to respond to immune challenge. These cumulative age-associated changes…

Prognostic Value of Geriatric Conditions Beyond Age After Acute Coronary Syndrome

2016

The aim of the present study was to investigate the prognostic value of geriatric conditions beyond age after acute coronary syndrome. This was a prospective cohort design including 342 patients (from October 1, 2010, to February 1, 2012) hospitalized for acute coronary syndrome, older than 65 years, in whom 5 geriatric conditions were evaluated at discharge: frailty (Fried and Green scales), comorbidity (Charlson and simple comorbidity indexes), cognitive impairment (Pfeiffer test), physical disability (Barthel index), and instrumental disability (Lawton-Brody scale). The primary end point was all-cause mortality. The median follow-up for the entire population was 4.7 years (range, 3-2178 …

The loss of muscle mass and sarcopenia: non hormonal intervention.

2011

Muscle aging is a key component of the increase in frailty in human populations. The generation of critical levels of power is a prerequisite to perform simple tasks of daily living, such as rising from a chair or climbing stairs. There is great scientific and social interest to determine which behaviors can lead to the maintenance of the muscle mass in young immobilized subjects and in the elderly. Several hormonal treatments have been proposed for the treatment of sarcopenia. However, the side effects associated to these treatments emphasize the need of finding non-toxic and non-hormonal treatments that help increase muscle strength, improve muscle function, and decrease the degree of dep…

Disability, physical activity, and muscle strength in older women: The women's health and aging study

1999

Abstract Objective: To study associations of motor disability, physical activity, and muscle strength in older women, in particular to investigate whether model of spiraling decrease is expressed in the data. Design: Cross-sectional analysis using data from the base-line measurements of The Women's Health and Aging Study (WHAS). Setting: Participants' homes. Participants: A total of 1,002 disabled women aged 65 years and older living in the community. Outcome Measures: Motor disability was measured by the number of self-reported difficulties in grasping, lifting 101b, walking across a small room, walking 14 mile, climbing 10 steps, and doing heavy housework. Level of physical activity was d…

The relationship between depression and frailty syndrome: a systematic review

2014

Frailty is a geriatric syndrome characterised by the clinical presentation of identifiable physical alterations such as loss of muscle mass and strength, energy and exercise tolerance, and decreased physiological reserve. Frailty and depressive symptoms are common issues facing older adults and may be associated. It is not clear if the depression facilitates the appearance of frailty syndrome or vice versa or these two coexist independently in the same individuals.We performed searches in several databases (Embase, PubMed, CINAHL, Scopus, and PsycINFO) papers published between November 2003 to February 2014 about frailty syndrome and depression in people aged 65 and older published and the …