Search results for "elderly."
showing 10 items of 850 documents
Advanced age is an independent risk factor for severe infections and mortality in patients given anti-tumor necrosis factor therapy for inflammatory …
2011
See related article, Oostlander AE et al, on page 116 in Gastroenterology. BACKGROUND & AIMS: Few data are available on effects of biologic therapies in patients more than 65 years old with inflammatory bowel disease (IBD). We evaluated the risk and benefits of therapy with tumor necrosis factor (TNF) inhibitors in these patients. METHODS: We collected data from patients with IBD treated with infliximab (n 2475) and adalimumab (n 604) from 2000 to 2009 at 16 tertiary centers. Ninety-five patients (3%) were more than 65 years old (52 men; 37 with ulcerative colitis and 58 with Crohn’s disease; 78 treated with infliximab and 17 with adalimumab). The control group comprised 190 patients 65 yea…
Early life determinants of frailty in old age : the Helsinki Birth Cohort Stud
2018
Background there is evidence suggesting that several chronic diseases have their origins in utero and that development taking place during sensitive periods may affect the aging process. We investigated whether early life determinants would be associated with frailty in old age. Methods at a mean age of 71 years, 1,078 participants belonging to the Helsinki Birth Cohort Study were assessed for frailty according to the Fried frailty criteria. Early life measurements (birth weight, length, mother body mass index [BMI] and parity) were obtained from birth, child welfare and school health records. Multinomial regression analysis was used to assess the association between early life determinants…
Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up.
2017
This study investigated the effects of resistance training (RT) performed with different frequencies, including a follow-up period, on cardiorespiratory fitness in healthy older individuals. Eighty-eight men and women (69 ± 3 years, 167 ± 9 cm and 78 ± 14 kg) were randomly placed into four groups: training one- (M1 = 11, W1 = 12), two- (M2 = 7, W2 = 14), or three- (M3 = 11, W3 = 13) times-per-week or a non-training control group (MCon = 11, WCon = 9). During months 1–3, all subjects trained two-times-per-week while during the subsequent 6 months, training frequency was set according to the group. Oxygen consumption (cycling economy: CE), gross efficiency (GE), blood lactate concentrations (…
Effects of different strength training frequencies on maximum strength, body composition and functional capacity in healthy older individuals
2017
There is controversy in the literature regarding the dose-response relationship of strength training in healthy older participants. The present study determined training frequency effects on maximum strength, muscle mass and functional capacity over 6 months following an initial 3-month preparatory strength training period. One-hundred and six 64–75 year old volunteers were randomly assigned to one of four groups; performing strength training one (EX1), two (EX2), or three (EX3) times per week and a non-training control (CON) group. Whole-body strength training was performed using 2–5 sets and 4–12 repetitions per exercise and 7–9 exercises per session. Before and after the intervention, ma…
Training load does not affect detraining's effect on muscle volume, muscle strength and functional capacity among older adults
2017
Research underlines the potential of low-load resistance exercise in older adults. However, while the effects of detraining from high-load protocols have been established, it is not known whether gains from low-load training would be better/worse maintained. The current study evaluated the effects of 24weeks of detraining that followed 12weeks of high- and low-load resistance exercise in older adults. Fifty-six older adults (68.0±5.0years) were randomly assigned to leg press and leg extension training at either HIGH load (2×10-15 repetitions at 80% of one-repetition maximum (1-RM)), LOW load (1×80-100 repetitions at 20% of 1-RM), or LOW+ load (1×60 repetitions at 20% of 1-RM, immediately fo…
High intensity interval resistance training (HIIRT) in older adults: Effects on body composition, strength, anabolic hormones and blood lipids
2017
The aging process induces significant changes in skeletal muscle morphology and functionality. If not counteracted, this process, termed sarcopenia, can lead to progressively greater disability, frailty and loss of independence. Whilst determining the prevalence of sarcopenia at the population level is complicated by different diagnostic criteria and methodologies used to assess muscle mass, a large percentage of older adults will suffer from this condition in their lifetime (von Haehling et al., 2010). Additionally, longer life expectancy is producing a growing number of elderly individuals worldwide (Beard et al., 2016). Therefore, age-related diseases, such as sarcopenia, are an increasi…
Group fitness activities for the elderly: an innovative approach to reduce falls and injuries
2013
Aim The aim of this study was to examine the opportunity to adopt, for the elderly, already validated function ability tests to better understand how to prevent falls and injuries and to better plan group fitness activities like ballroom dance classes (e.g., Valzer, Polka, Mazurka). Methods A cross-sectional study was conducted. The Berg Balance Scale (BBS) and the Barthel Index (BI) were administered and the occurrence of falls during the previous 2 years was evaluated by anamnesis. One hundred and twenty-two elderly subjects living in Palermo city participated to the study. According to the anamnesis, subjects were divided into two groups: experimental group (EG) and control group (CG). T…
A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail E…
2016
Abstract Background Frailty can be an important clinical target to reduce rates of disability. Objective To ascertain if a supervised-facility multicomponent exercise program (MEP) when performed by frail older persons can reverse frailty and improve functionality; cognitive, emotional, and social networking; as well as biological biomarkers of frailty, when compared with a controlled population that received no training. Design This is an interventional, controlled, simple randomized study. Researchers responsible for data gathering were blinded for this study. Setting Participants from 2 primary rural care centers (Sollana and Carcaixent) of the same health department in Spain were enroll…
Incidence rates of fragility hip fracture in middle-aged and elderly men and women in southern Norway.
2011
Background Hip fracture contributes to increased morbidity and mortality in the elderly population. As the average age of the population is increasing, the burden of hip fracture on the health-care system is a growing challenge. The highest incidence of hip fracture worldwide has been reported from Scandinavia in fact from Oslo the capital of Norway. During the last decades, efforts have been undertaken to reduce hip fracture risk. Objective To study the incidence of fragility hip fracture in southern Norway. Design A validated retrospective epidemiological study. Setting Population-based study. Subjects All patients with fragility hip fractures aged 50 years or older in 2004 and 2005 in so…
Subjective and objective sleep quality in elderly individuals: The role of psychogeriatric evaluation
2018
[EN] Aging affects sleep and sleep problems are common in older individuals. However, the relationship between objective and subjective tools for analysing sleep and psycho-geriatric variables have not been tested in institutionalised older individuals. This work analyses sleep quality by using actigraphy as an objective tool and validates the Athens and Oviedo sleep questionnaires in octogenarian elderly individuals as subjective scales of sleep perception. All patients wore an actigraph device for one week and then completed the Athens and Oviedo clinical sleep-evaluation questionnaires. Morning cortisol levels in blood plasma and saliva samples were also measured to assess the associatio…